Ethnobotany and preliminary bioactivity investigation on hepatoprotective medicinal plants from the Mouhoun Region of Burkina Faso

Authors

  • Jotham Yhi-pênê N'DO Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso
  • André TIBIRI 1 Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso. 2 Institute for Research in Health Sciences (IRSS / CNRST), Department of Medicine and Traditional Pharmacopoeia (MEPHATRA-PH), 03 BP 7192 Ouaga 03, Burkina Faso
  • Ernest Nogma SOMBIE Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso
  • Tata Kadiatou TRAORE Doctoral School of Health / University of Ouagadougou, PO Box 7021, Burkina Faso
  • Noufou OUEDRAOGO Institute for Research in Health Sciences (IRSS / CNRST), Department of Medicine and Traditional Pharmacopoeia (MEPHATRA-PH), 03 BP 7192 Ouaga 03, Burkina Faso
  • Adama HILOU Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso.
  • Pierre Innocent GUISSOU 2 Institute for Research in Health Sciences (IRSS / CNRST), Department of Medicine and Traditional Pharmacopoeia (MEPHATRA-PH), 03 BP 7192 Ouaga 03, Burkina Faso 3 Doctoral School of Health / University of Ouagadougou, PO Box 7021, Burkina Faso
  • Odile Germaine NACOULMA Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso.

Keywords:

hepatoprotection, Medicinal plants, antioxidant activity, Mouhoun region, Burkina Faso

Abstract

An ethnobotanical survey of medicinal plants used to treat hepatitis in the Mouhoun region of Burkina Faso was undertaken. The extracts of the most quoted species were then evaluated for their phytochemistry and their antioxidant activity The anti-radical activity (by the method of the discoloration of the ABTS cation radical) and that of the antioxidant (by the method of the reduction of the iron ion, FRAP) were evaluated. Then the phenolic content of the aqueous extracts was determined and a correlation was studied between these two parameters. The antioxidant tests showed that the plants counted have a good antioxidant power. The three most active extracts are those of the trunk and root bark of Pseudocedrela kostchyi, and the trunk bark of Sterculia setigera. The extract of the bark of the trunk of Sterculia setigera showed the highest total tannin and phenolic content, while that of the leaves of Piliostigma reticulatum showed the highest content of flavonoids. The analyses showed that there is a relationship between the total phenolic contents and the antioxidant capacities of all the extracts (R2 = 0.82). The extracts of the trunk and root barks of Pseudocedrela kostchyi, and that of the trunk bark of Sterculia setigera showed the best antioxidant properties. They could be good candidates for the search for liver protective molecules

References

. WHO, "Hepatitis: Improved health of people with viral hepatitis, 2014; 12:1-6.

Pietra V, Kiema J, Sorghum D, Kabore SPC, Mande S, Castelli F, Puoli MR, and Simporé J. Prevalence of markers of hepatitis B and antibodies against Hepatitis C virus among health personnel in Nanoro, Burkina Faso. Science and Technology. Health Science. 2008; 31:59.

Konate K. Phytochemistry and Research Potential hepatoprotective and extracts of immunostimulant Cienfuegosia digitata Cav., And Sida alba L. (Malvaceae) traditionally used against hepatic diseases for the treatment of viral hepatitis B. University of Ouagadougou. 2012; 1:170-180.

Ouattara MB, Kiendrébbéogo MR, Konate K, Compaoré M, Meda RN, Bationo JH, Millogo-Rasolodimby J, Thiombiano A and NACOULMA OG. Potential Antibacterial and Antioxidant Activity of Polyphenols of Sesbania pachycarpa Antibacterial Potential And Antioxidant Activity of Polyphenols of Sesbania. African Journal of Scientific Research. 2011; 5:1-17.

The figures in the region of Mouhoun. National Institute of Statistics and Demography (INSD) and Ministry of Economy and Finance of Burkina Faso. on insd.bf (2011 edition). 2011 .

Region BN. National Institute of Statistics and Demography (INSD) and Ministry of Economy and Finance of Burkina Faso. Insd.bf. 2013; 20:7-9.

Dabat MH. Agricultural Market of the Regions Boucle du Mouhoun, Center, Hauts Bassins, Sahel. 2010.

Didier P. Traditional Medicine and Integrative Medicine. 2016.

Yelemou B, Bationo BA, Yameogo G, Millogo-Rasolodimby J. Traditional management and use of Piliostigma reticulatum on the Central Plateau of Burkina Faso traditional used. Woods and forests of the tropics. 2007; 291: 55-66.

Pellegrini RR, Prottegent NA, Pannala A, Yang M, Rice-Evans C. Radical Biology and Medicine, flight. 1999; 5:1231-1237.

Kroyer GT. Red clover extract as antioxidant active and functional food ingredient. Innovative Food Science & Emerging Technologies. 2004; 5: 101-105.

Apati P, Szentmihalyi K, Kristo S, Papp I, Vinkler P, Szoke E, Kery A. Herbal Remedies of Solidago - correlation of phytochemical characteristics and antioxidative properties. Pharmaceutical and Biomedical Analysis. 2003; 32: 1045-1053.

Singleton VL, Orthofer R, Lamuela R, Rosa M. Analysis of total phenols and other oxidation substrates and antioxidants by means of folin-ciocalteu reagent. In Enzymology Academic Press. 1999; 299: 152-178.

Tibiri A, Ouedraogo R, Nacoulma GO, Banzouzi JT. Radical Scavenging Activity, Phenolic Content and Cytotoxicity of Entada africana Guill. And Perr. (Mimosaceae). Journal of Biological Sciences. 2007; 6: 959-963.

Abdel-Hameed ESS. Total phenolic contents and free radical scavenging activity of certain Egyptian Ficus species leaf samples. Food Chem. 2009; 114(4):1271-1277.

Bekalo TH, Woodmatas SD, Woldemariam ZA. An ethnobotanical study of medicinal plants used by local people in the lowlands of Konta Special Woreda , southern nations , nationalities and peoples regional state , Ethiopia. 2009;15 : 18.

Deeni YY, Sadiq NM. No TitleAntimicrobial properties and phytochemical con-stituents of the leaves of African mistletoe (Tapinanthus dodoneifolius (DC) Dancing) (Loranthaceae) year ethnomedicinal plant of Hausaland, Northern Nigeria. Journal of Ethnopharmacology. 2002; 83: 235-240.

Wondimu T, Asfaw Z, Kelbessa E. Ethnobotanical study of medicinal plants around 'Dheeraa' town, Arsi Zone, Ethiopia. Journal of Ethnopharmacology. 2007; 112: 152-161.

Yineger H, Yehuwalaw D. Traditional medicinal plant knowledge and use by local healers in Sekoru District, Jimma Zone, Southwestern Ethiopia. Ethnobiol Ethnomed J. 2007; 3:20-24.

Ashagre M, Asfaw Z, Kelbessa E. Ethnobotanical study of wild edible plants in Burji District, Segan area zone of southern nations, nationalities and peoples region (SNNPR) Ethiopia. Journal of Ethnobiology and Ethnomedicine. 2016; 12:32.

Tadesse M, Hunde D, Getachew Y. Survey of medicinal plants used to treat human diseases in Seka Cherkosa, Jimma Zone, Ethiopia. Ethiop J Health. 2005; 15:89–106.

Manach C, Scalbert A, Morand C, Réméry C, Jiménez L. Polyphenils, food source and biovailabality. Am. J. Clin. Nutr. 2004. 79:727-747.

Balasundram N, Sundram K, Samar S. Phenolic compounds in plants and agric-industrial by products. Antioxidant activity, occurrence, and potential uses. Food Chem. 2006; 1:191-203.

Osemeahon SA, Barminas J, Aliyu BA, Nkafamiya II. Development of sodium alginate and konkoli gum grafted-polyacrylamide blend membrane: optimization of grafting conditions. African Journal of Biotechnology. 2008; 7:1309-1313.

Ionescu E. eugen ionescu scholarship program 2014-2015 hospital universities and their research themes, 2015; 1:24.

Catalfamo M, Le SC, Lane HC. The role of cytokines in the pathogenesis and treatment of HIV infection. Cytokine Growth Factor Rev. 2012;23:207–14.

Khaliq I, Hof C, Prinzinger R, Bo¨hning-Gaese K, Pfenninger M. Global variation in thermal tolerances and vulnerability of endotherms to climate change. Proc. R. Soc. 2014; 281:5-7.

Oyedemi SO, Yakubu MT, Afolayan AJ. Antidiabetic activities of aqueous leaves extract of Leonotis leonurus in streptozotocin induced diabetic rats. Journal of Medicinal Plants Research. 2011; 5:119-125.

Oyedemi SO, Yakubu MT, Afolayan AJ. Antidiabetic activities of aqueous leaves extract of Leonotis leonurus in streptozotocin induced diabetic rats. Journal of Medicinal Plants Research, 2011; 5:119-125.

Ugulu I, Baslar S, Yorek N, Dogan Y. The investigation and quantitative ethnobotanical evaluation of medicinal plants used around Izmir province, Turkey. 2009; 5: 345-367.

Meda NTR, Bangou J, Bakasso S, Nacoulma OG. Antioxidant activity of phenolic and flavonoid fractions of Cleome gynandra and Maerua angolensis of Burkina Faso. Journal of Applied Pharmaceutical Science. 2013; 3:36-42.

Sarkar MK, Sil PC. Hepatocytes are protected by herb Phyllanthus niruri protein isolate against thioacetamide toxicity. Pathophysiology. 2007; 14: 113-120.

Evans JF, Ferguson AD, Mosley RT, Hutchinson JH. What's all of the FLAP about: 5-lipoxygenase-activating protein. In Trends in Pharmacological Sciences. 2008; 2: 72-79.

Downloads

Published

30-06-2018

How to Cite

1.
Jotham Yhi-pênê N’DO, André TIBIRI, Ernest Nogma SOMBIE, Tata Kadiatou TRAORE, Noufou OUEDRAOGO, Adama HILOU, Pierre Innocent GUISSOU, Odile Germaine NACOULMA. Ethnobotany and preliminary bioactivity investigation on hepatoprotective medicinal plants from the Mouhoun Region of Burkina Faso. ijp [Internet]. 2018 Jun. 30 [cited 2024 Oct. 22];10(2):73-80. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/592

Issue

Section

Original Research Articles

Most read articles by the same author(s)