Ethnobotany and preliminary bioactivity investigation on hepatoprotective medicinal plants from the Mouhoun Region of Burkina Faso

Authors

  • Jotham Yhi-pênê N'DO Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso
  • André TIBIRI 1 Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso. 2 Institute for Research in Health Sciences (IRSS / CNRST), Department of Medicine and Traditional Pharmacopoeia (MEPHATRA-PH), 03 BP 7192 Ouaga 03, Burkina Faso
  • Ernest Nogma SOMBIE Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso
  • Tata Kadiatou TRAORE Doctoral School of Health / University of Ouagadougou, PO Box 7021, Burkina Faso
  • Noufou OUEDRAOGO Institute for Research in Health Sciences (IRSS / CNRST), Department of Medicine and Traditional Pharmacopoeia (MEPHATRA-PH), 03 BP 7192 Ouaga 03, Burkina Faso
  • Adama HILOU Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso.
  • Pierre Innocent GUISSOU 2 Institute for Research in Health Sciences (IRSS / CNRST), Department of Medicine and Traditional Pharmacopoeia (MEPHATRA-PH), 03 BP 7192 Ouaga 03, Burkina Faso 3 Doctoral School of Health / University of Ouagadougou, PO Box 7021, Burkina Faso
  • Odile Germaine NACOULMA Laboratory of Biochemistry and Applied Chemistry (LABIOCA) / University of Ouagadougou, 03 BP 848 Ouagadougou 03, Burkina Faso.

Keywords:

hepatoprotection, Medicinal plants, antioxidant activity, Mouhoun region, Burkina Faso

Abstract

An ethnobotanical survey of medicinal plants used to treat hepatitis in the Mouhoun region of Burkina Faso was undertaken. The extracts of the most quoted species were then evaluated for their phytochemistry and their antioxidant activity The anti-radical activity (by the method of the discoloration of the ABTS cation radical) and that of the antioxidant (by the method of the reduction of the iron ion, FRAP) were evaluated. Then the phenolic content of the aqueous extracts was determined and a correlation was studied between these two parameters. The antioxidant tests showed that the plants counted have a good antioxidant power. The three most active extracts are those of the trunk and root bark of Pseudocedrela kostchyi, and the trunk bark of Sterculia setigera. The extract of the bark of the trunk of Sterculia setigera showed the highest total tannin and phenolic content, while that of the leaves of Piliostigma reticulatum showed the highest content of flavonoids. The analyses showed that there is a relationship between the total phenolic contents and the antioxidant capacities of all the extracts (R2 = 0.82). The extracts of the trunk and root barks of Pseudocedrela kostchyi, and that of the trunk bark of Sterculia setigera showed the best antioxidant properties. They could be good candidates for the search for liver protective molecules

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Published

30-06-2018

How to Cite

1.
Jotham Yhi-pênê N’DO, André TIBIRI, Ernest Nogma SOMBIE, Tata Kadiatou TRAORE, Noufou OUEDRAOGO, Adama HILOU, Pierre Innocent GUISSOU, Odile Germaine NACOULMA. Ethnobotany and preliminary bioactivity investigation on hepatoprotective medicinal plants from the Mouhoun Region of Burkina Faso. ijp [Internet]. 2018 Jun. 30 [cited 2024 Dec. 7];10(2):73-80. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/592

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