The relevance of Asteraceae family plants in most of the neuropsychiatric disorders treatment
Keywords:
Asteraceae, Neuropsychiatry, animal models, Alzheimer, Parkinson, autismAbstract
Many of the traditional medicinal plants belong to one of the largest plant families: the Asteraceae family. These plants are widely used in alternative medicine due to their effects on the nervous system, being studied both on cellular and animal models. In this way, medicinal plants are preferred in drug therapy research due to the wide population interest. The Asteraceae plants phytochemical composition is mainly consisted in cholinergic, dopaminergic or serotonergic molecules which are involved in the pathophysiology of the neuropsychiatric disorders such as Alzheimer’s disease, Parkinson’s disease, schizophrenia, autism, anxiety or depression. Therefore, this review aims to comprise all the available information regarding the neurological activity of Asteraceae family plants in order to find further correlations between different components in order to explain their neuropsychiatric potential use.
References
Bitsindou M, Lejoly J, Van Essghe K. Les plantes employées contre les affections hépatiques en médecine traditionnelle africaine. Médicaments et aliments: l’approche ethnopharmacologique. Actes du 2e Colloque Européen d'Ethnopharmacologie et de la 1le Conférence internationale d'Ethnomédecine, Heidelberg, 1993; 163-166.
Nacoulma OG. Plantes médicinales et pratiques médicales traditionnelles au Burkina Faso: Cas du plateau central, Tome I & II. Thèse de doctorat d’état ès Sciences Naturelles, Université de Ouagadougou; Département de Biochimie-Microbiologie, 1996.
Laekeman G, De Coster S, De Meyer K. Le chardon Marie: Aperçu de l'ONU. Journal de Pharmacie de Belgique 2003; 58 (1): 28-31.
Maelicke A, Samochocki M, Jostock R, Fehrenbacher A, Ludwig J, Albuquerque EX, Zerlin M. Allosteric sensitization of nicotinic receptors by galantamine, a new treatment strategy for Alzheimer’s disease. Biological Psychiatry 2001; 49(3): 279-288.
Lefter R, Cojocaru D, Ciobica A, Paulet IM, Serban IL, Anton E. Aspects of animal models for major neuropsychiatric disorders. Archives of Biological Sciences 2014; 66 (3): 1105-1115.
Ciobica A, Padurariu M, Dobrin R, Stefanescu C, Dobrin R. Oxidative stress in schizophrenia focusing on the main markers. Psychiatria Danubina 2011; 23(3):237-45.
Padurariu M, Ciobica A, Lefter R, Serban IL, Stefanescu C, Chirita R. The Oxidative stress Hypothesis in Alzheimer’s disease. Psychiatria Danubina 2013; 25(4):401-409.
Nelson-Harrison ST, King SR, Limbach C, Jackson C, Galiwango A, Kato SK, Kanyerezi BR. Ethnobotanical research into the 21st century. In: Iwu, M.M., Wootton, J.C. (Eds.), Ethnomedical and Drug Discovery 2002; 1:283- 307.
Sayyah M, Boostani H, Pakseresht S, Malayeri A. Comparison of Silybum marianum (L.) Gaertn. With fluoxetine in the treatment of obsessive-compulsive disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2010; 34(2):362-5.
Luedtke RR, Freeman RA, Volk M, Arfan M, Reinecke MG. Pharmacological survey of medicinal plants for activity at dopamine receptor subtypes. II. Screen for binding activity at the d1 and d2 dopamine receptor subtypes. Pharmaceutical Biology 2003; 41 (1): 45-58.
Banji D, Banji OJ, Annamalai AR, Shanthmurthy M. Impact of the aqueous extract of Eclipta alba on maternal aggression in rats. Pakistan Journal of Pharmaceutical Sciences 2010; 23(2):138-142.
García-García PI, López-Muñoz F, Rubio G, Martín-Agueda B, Alamo C. Phytotherapy and psychiatry: bibliometric study of the scientific literature from the last 20 years. Phytomedicine 2008; 15(8):566-76.
Philander L. An ethnobotany of Western Cape Rasta bush medicine. Journal of Ethnopharmacology 2011; 138: 578-594.
Picard G. Discovery of novel neurologically active phytochemicals in Neotropical Piperaceae: an ethnopharmacological approach. Thesis submitted to the Faculty of Graduate and Postdoctoral Studies, University of Ottawa, Ottawa-Carleton Institute of Biology, 2011.
Jäger AK, Hutchings A, Van Staden J. Screening of Zulu medicinal plants for protaglandin-synthesis inhibitors. Journal of Ethnopharmacology 1996; 52: 95-100.
Perry E, Howes M. Medicinal Plants and Dementia Therapy: Herbal Hopes for Brain Aging? CNS Neuroscience & Therapeutics 2011; 17: 683-698.
Saxena S, Brody AL, Schwartz JM, Baxter LR. Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder. The British Journal of Psychiatry 1998; 173 (Suppl 35): 26-37.
Chamberlain SR, Fineberg NA, Menzies LA, Blackwell AD, Bullmore ET, Robbins TW, Sahakian BJ. Impaired cognitive flexibility and motor inhibition in unaffected first-degree relatives of patients with obsessive-compulsive disorder. American Journal of Psychiatry 2007; 164 (2): 335-338.
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (DSM-IV-TR). Washington, DC: American Psychiatric Press, 2000.
Goodman WK, Price LM, Rasmussen SA, Mazure C, Fleischman RL, Hill CL, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale I. Development, use, and reliability. Archives of General Psychiatry 1989; 46 (11):1006-1011.
Kaplan & Saddock. Comprehensive handbook of psychiatry. 8th ed. Lippincott Williams & Wilkins; 2005; 2888-914.
Ramezani M, Azarabadi M, Fallah Huseini H, Abdi H, Baher G, Huseini M. The effects of Silybum marianum (L.) Gaertn. seed extract on glycemic control in type II diabetic patient's candidate for insulin therapy visiting endocrinology clinic in Baqiyatallah Hospital in the years of 2006. Journal of Medicinal Plants Research 2008; 7(26):79-84.
Saidi H, Mofidi M. Toxic effect of Xanthium strumarium as an herbal medicine preparation. EXCLI Journal 2009; 8:115-117.
Wang Y, Hamburger M, Cheng CH, Costall B, Naylor RJ, Jenner P, Hostettmann K. Neurotoxic sesquiterpenoids from the yellow star thistle Centaurea solstitialis L. (Asteraceae). Helvetica Chimica Acta 1991; 74 (1): 117-123.
Taïwe GS, Ngo Bum E, Talla E, Dawe A, Moto OF, Ngoupaye GT, Sidiki N, Dabole B, Dzeufiet PD, Dimo T, De Waard M. Antipsychotic and sedative effects of the leaf extract of Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae) in rodents. Journal of Ethnopharmacology 2012; 143: 213-220.
Irwin S. Comprehensive observational assessment: A systemic, quantitative procedure for assessing the behavioral and physiological state of the mouse. Psychopharmacology 1968; 13:222–257.
Ajayi AA, Ukponmwan OE. Evidence of angiotensin II and endogenous opioid modulation of novelty induced rearing in the rat. African Journal of Medicine and Medical Sciences 1994; 23: 287-290.
Labella FS, Punsky C, Havlicek V. Morphine derivatives with diminished opiate receptor potency show enhanced control excitatory activity. Brain Research 1979; 174: 263-271.
Kenneth SK, Kenneth ID. Genetic control of apomorphine-induced climbing behaviour in two inbred mouse strains. Brain Research 1984; 293: 343-351.
Sanberg PR, Bunsey MD, Giordano M, Norman AB. The catalepsy test: its ups and downs. Behavioural Neuroscience 1988; 102: 748-759.
Gonzalez-Trujano ME, Navarrete CA, Reyes B, Hong E. Some pharmacological effects of the ethanol extract of leaves of Annona diversifolia on the central nervous system in mice. Phytotherapy Research 1998; 2: 600-602.
Lowe IP, Robins E, Eyermen GS. The fluorimetric measurement of glutamic decarboxylase and its distribution in brain. Journal of Neurochemistry 1958; 3: 8-16.
Sutton I, Simmonds M. Effects of acute and chronic pentobarbitone on the γ-aminobutyric acid system in rat brain. Biochemical Pharmacology 1974; 23: 1801-1808.
Chapouthier G, Venault P. A pharmacological link between epilepsy and anxiety? Trends in Pharmacological Sciences 2001; 22 (10): 491-493.
Yamamotova A, Pometlova M, Harmatha J, Raŝkova H, Rokyta R. The selective effect of N-feruloylserotonins isolated from Leuzea carthamoides on nociception and anxiety in rats. Journal of Ethnopharmacology 2007; 112: 368-374.
Porsolt RD, Anton G, Blavet N, Jalfre M. Behavioural despair in rats: A new model sensitive to anti-depressant treatments. European Journal of Pharmacology 1978; 47: 379-391.
Mogil JS, Sternberg WF, Balian H, Liebeskind JC, Sadowski B. Opioid and nonopioid swim stress-induced analgesia: a parametric analysis in mice. Physiology & Behaviour 1996;59:123-132.
D’Amour FE, Smith DL. A method for determining loss of pain sensation. Journal of Pharmacology and Experimental Therapeutics 1941; 72: 74-79.
Le Bars D, Gozariu M, Cadden SW. Animal models of nociception. Pharmacological Reviews 2001; 53: 597-652.
Pellow S, Chopin PH, File SE, Briley M. Validation of open: closed arm entries in an elevated plus-maze as a measure of anxiety in the rat. Journal of Neuroscience Methods 1985; 14: 149-167.
Azmat A, Ahmed M, Navaid-Ul-Zafar N, Ahmad SI. Neuropharmacological profile of somina (herbal drug) in mice and rats. Pakistan Journal of Pharmacology 2008; 25(2):53-58.
Khan U. Indusynic medicine traditional medicine of herbal, animal and mineral origin in Pakistan, Department of Pharmacognosy, Faculty of Pharmacy, University of Karachi, 1997; 269-270, 325-326, 397-398.
Dandiya PC, Kulkarni SK. A Study of the Open Field Behaviour as a Single Parameter. Indian Journal of Pharmacology 1975; 7 (4): l-4.
Dandiya PC, Collumbine H. Studies on Acorus calamus (III): Some pharmacological actions of the volatile oil. Journal of Pharmacology and Experimental Therapeutics 1959; 125: 353-359.
Hozumi S, Nakagawasai O, Tan-No K, Niijima F, Yamadera F, Murata A, Araj Y, Yasuhara H, Tadano T. Characteristics of changes in cholinergic function and impairment of learning and memory-related behavior induced by olfactory bulbectomy. Behavioural Brain Research 2003; 138:9-15.
Haider S, Haleem DJ. Decrease of brain serotonin following 4 weeks of food restriction in male and female rats. Medical Sciences Moniter 2000; 6 (6): 1061-1067.
Breier A. Serotonin, schizophrenia and antipsychotic drug action. Schizophrenia Research 1995; 14(3):187-202.
Heisler LK, Chu HM, Brennan TJ, Danao JA, Bajwa P, Parsons LH, Tecott LH. Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice. Proceedings of the National Academy of Sciences 1998; 95 (25): 15049-15054.
Zhao ZZ, Ksiezak-Reding H, Silvana Riggio S, Haroutunian V, Pasinetti GM. Insulin receptor deficits in schizophrenia and in cellular and animal models of insulin receptor dysfunction. Schizophrenia Research 2006; 84: 1-14.
Li Y, Perry TA, Kindy MS, Harvey BK, Tweedie D, Holloway HW, Powers K, Shen H, Egan JM, Sambamurti K, Brossi A, Lahiri DK, Mattson MP, Hoffer BJ, Wang Y, Greig NH. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. PNAS 2009; 106 (4): 1285-1290.
Adewusi EA, Moodley N, Steenkamp V. Medicinal plants with cholinesterase inhibitory activity: a review. African Journal of Biotechnology 2010; 9(49): 8257-8276.
Ribeiro VLS, Vanzella C, Moysés FS, Dos Santos JC, Martins JRS, Von Poser JL, Siqueira IR. Effect of Calea serrata Less. n-hexane extract on acetylcholinesterase of larvae ticks and brain Wistar rats. Veterinary Parasitology 2012; 189: 322-326.
Ellman GL, Courtney KD, Anders VJR, Featherstone RM. A new rapid colorimetric determination of acetylcholinesterase activity. Biochemical Pharmacology 1961; 7: 88-95.
Baxter GD, Green P, Stuttgen M, Barker SC. Detecting resistance to organophosphates and carbamates in the cattle tick Boophilus microplus, with a propoxur-based biochemical test. Experimental and Applied Acarology 1999; 23: 907-914.
Guenné S, Ouattara N, Hilou A, Millogo JF, Nacoulma OG. Antioxidant, enzyme inhibition activities and polyphenol contents of three Asteraceae species used in Burkina Faso traditionally medicine. International Journal of Pharmacy and Pharmaceutical Sciences 2011; 3(5):524-28.
Bangou MJ, Kiendrebeogo M, Compaore M, Coulibaly AY, Meda NTR, Abarca NA, Zeba B, Millogo Rosalodimby J, Nacoulma OG. Enzymes inhibition effects and polyphenol content of medicinal plant extracts from Burkina Faso. International Journal of Biological Sciences 2011; 11 (1): 31-38.
Guenné S, Hilou A, Meda NTR, Ouattara N, Kiendrebéogo M, Millogo JF, Nacoulma OG. Screening of antioxidant, anti-acetylcholinesterase and antifungal activities and HPLC-MS identification of bioactive phenolics of Eclipta alba (L.) Hassk. International Journal of Phytomedicine 2012; 4: 469-476.
Byrne GI, Lehmann LK, Kirschbaum JG, Borden EK, Lee CM, Brown RR. Induction of tryptophan degradation in vitro and in vivo: a gamma- interferon-stimulated activity. Journal of Interferon & Cytokine Research 1986; 6: 389-396.
Schroecksnadel K, Wirleitner B, Winkler C, Fuchs D. Monitoring tryptophan metabolism in chronic immune activation. Clinical Chemica Acta 2006; 364: 82-90.
Temml V, Kuehnl S, Schuster D, Schwaiger S, Stuppner H,
Fuchs D. Interaction of Carthamus tinctorius lignan arctigenin with the binding site of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase. FEBS Open Bio 2003; 3: 450-452.
Wolber G, Langer T. Ligand Scout: 3-d pharmacophores derived from protein-bound ligands and their use as virtual screening filters. Journal of Chemical Information and Modeling 2015; 45: 160-169.
Sugimoto H, Oda S, Otsuki T, Hino T, Yoshida T, Shiro Y. Crystal structure of human indoleamine 2,3-dioxygenase: catalytic mechanism of O2 incorporation by a heme-containing dioxygenase. Proceedings of the National Academy of Sciences USA 2006; 103: 2611-2616.
Hawkins PC, Skillman GA, Warren GL, Ellingson BA, Stahl MT. Conformer generation with OMEGA: algorithm and validation using high quality structures from the protein databank and Cambridge structural database. Journal of Chemical Information and Modeling 2010; 50: 572-584.
Accelrys Software Inc. Discovery studio modeling environment, Release 3.5, 2012, San Diego: Accelrys Software Inc., http://accelrys.com/products/ discovery-studio/.
Molecular Operating Environment (MOE). Chemical Computing Group Inc., 1010 Sherbooke St. West, Suite #910, Montreal, QC, Canada, H3A 2R7, 2010.
Scatchard G. The attractions of proteins for small molecules and ions. Annals of the New York Academy of Sciences 1949; 51: 660- 672.
Shimizu H, Daly JW, Creveling CR. A radioisotopic method for measuring the formation of adenosine 3′, 5′-cyclic monophosphate in incubated slices of brain. Journal of Neurochemistry 1969; 16(12):1609-1619.
Luedtke RR, Griffin SA, Conroy SS, Jin X, Pino A, Sesack SR. Immunoblot and immunohistochemical comparison of murine monoclonal antibodies specific for the rat D1a and D1b dopamine receptor subtypes. Journal of Neuroimmunology 1996; 101:170-187.
Luedtke RR, Freeman RA, Boundy VA, Martin MW, Huang Y, Mach RH. Characterization of (125)I-IABN, a novel azabicyclononane benzamide selective for D2-like dopamine receptors. Synapse 2000; 38: 438-449.
Ferrara L. Use of Chrysantellum americanum (L.) Vatke as supplement. European Scientific Journal 2013; 9 (36): 1857-7881.
