Memory Enhancing Effect of Ethanolic Extract of Stevia rebaudiana (Bert.)


  • Divya S Juyal Department of Pharmacy, Kumaun University, Bheemtal (Nainital), Uttrakhand, India 263631.
  • Ganga Bisht Department of Chemistry, Kumaun University, Nainital, Uttrakhand, India 263631.
  • Arun Kumar Department of Pharmacy, Kumaun University, Bheemtal (Nainital), Uttrakhand, India 263631.


Stevia rebaudiana, Memory, Alzheimer disease


Suspension of ethanolic extract of leaves of Stevia rebaudiana bert. in gum acacia were administered orally to evaluate the memory enhancing activity in the aged rats. Memory enhancing effect was evaluated by using Morris water maze and elevated plus maze. Mean escape latency time (ELT) calculated each day during acquisition trial was used as an index of acquisition and mean time spent in target quadrant in search of missing platform provided an index of retrieval. Significant reduction in transfer latency (TL) value of retention indicated improvement of memory. Significant memory enhancing effect of ethanolic extract Stevia rebaudiana was observed in aged rats at 200 mg/kg p.o. dose.


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How to Cite

Divya S Juyal, Ganga Bisht, Arun Kumar. Memory Enhancing Effect of Ethanolic Extract of Stevia rebaudiana (Bert.). ijp [Internet]. 2010 Jun. 30 [cited 2024 Jun. 21];2(2):166-71. Available from:



Original Research Articles