The Phytochemical Investigation and Biological Activities of Berberis Orthobotrys


  • Akber Dad Department of Chemistry, Karakoram International University, 15100-Gilgit, Gilgit-Baltistan, Pakistan
  • Iftikhar Ali Department of Chemistry, Karakoram International University, 15100-Gilgit, Gilgit-Baltistan, Pakistan
  • Nadja Engel Department of Cell Biology, University Medical Center Rostock, Schillingallee 69, 18059-Rostock, Germany
  • Muhammad Atif Division of Science & Technology, University of Education Vehari Campus, Punjab, Pakistan
  • Hidayat Hussain UoN Chair of Oman’s Medicinal Plants and Marine Natural Products University of Nizwa P.O Box 33, Postal Code 616 Birkat Al Mauz, Nizwa, Sultanate of Oman
  • Viqar Uddin Ahmad HEJ Research Institute of Chemistry, ICCBS, University of Karachi, Karachi-75270, Pakistan
  • Ivan R. Green Department of Chemistry and Polymer Science, University of Stellenbosch, P/Bag X1, Matieland, 7602, South Africa


Berberis orthobotrys, Bioassays, Sesamin, 10-Eicosanol


The leaf extract of Berberis orthobotrys Bien. ex Aitch. (B.o.) afforded three compounds viz., β-sitosterol (1), sesamin (2) and 10-eicosanol (3) which were identified by spectroscopic methods including 1D and 2D NMR, GC-MS, IR and comparison of their spectral data with the published data. To the best of our knowledge these three compounds are reported here for the first time to be isolated from Berberis orthobotrys Bien. ex Aitch. (B.o.). Moreover the root extract exhibited good antilieshmanial activity and root and fruit extracts demonstrated minor antifungal activity against Fusarium solani.


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How to Cite

Akber Dad, Iftikhar Ali, Nadja Engel, Muhammad Atif, Hidayat Hussain, Viqar Uddin Ahmad, Ivan R. Green. The Phytochemical Investigation and Biological Activities of Berberis Orthobotrys. ijp [Internet]. 2017 Jun. 30 [cited 2024 Jun. 23];9(2):213-8. Available from:



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