Potential Analgesic & Anti-Pyretic Herbal drugs: A Comparative Review of Marketed Products

Authors

  • Mukesh Kumar Singh Rungta College of Pharmaceutical Science & Research Kohka Road, Kurud, Bhilai-491024, India
  • Kushagra Nagori Rungta College of Pharmaceutical Science & Research Kohka Road, Kurud, Bhilai-491024, India
  • D.K Tripathi Rungta College of Pharmaceutical Science & Research Kohka Road, Kurud, Bhilai-491024, India.

Keywords:

Analgesic, Ayurvedic system, Herbal drugs, Antipyretic

Abstract

Analgesic from the family of the non-steroidal anti-inflammatory drugs (NSAIDs) have probably been used for more than 2000 years. In the 1900 ASA become an established treatment for pain and migraine. The detection of the main mechanism of the clinical effect of ASAs in John R.Vane’s group in 1972(who received the Nobel Prize for medicine in 1982 for his discovery of prostaglandin synthesis inhibition) gave a new and persistent drive to the development of other chemically different NSAID. The currently available analgesic and antipyretic drugs in allopathic system of medicine are not so effective in combating wide variety of complications. The remedial measure may lie in the ayurvedic system of medicine. The various herbal drugs such as Acacia nilotica, Bauhinia racemosa Linn. Cleome viscose, Hippobromus panciflorus etc known for their potential analgesic and antipyretic activity shall be discussed. The various branded herbal formulations like Rumalaya, Charak, Rumartho, Arthrella, and Reosto etc available in the market as analgesic and antipyretic remedies are also discussed along with their clinical merits. It may be concluded that since ayurvedic formulations contain number of ingredients in which one ingredient may act to enhance the action of other ingredient. Also as a result of so many ingredients present in the particular ayurvedic formulation it helps in combating other diseases in addition to analgesic and antipyretic activity.

References

Moon komal, Khadabadi SS, Deokate UA,

Deore SL. Caesalpinia bonducella F-An

Overview. Report and Opinian.2010; 2(3):

-90.

Gupta mradu, shaw BO, Mukherjee A. A

new glycosidic flavonoid from J warhar

mahakashay (antipyretic) Ayurvedic

preparation. International journal of

ayurvedic research.2010; 1(2):106-111.

Northover BJ, Subramanian G. analgesicantipyreticdrugs as inhibitors of kallikrein.

Brit. J.Pharmacol.1961; 17:107-115.

Mahesh S, Swati patil, Sachin R. Patil,

Ravi kumar, Patil MB. Evaluation of the

analgesic and antipyretic activities of

Ethanolic extract of male flowers

(inflorescences) of borassus Flabellifer L.

(arecaceae). International journal of

pharmacy and pharmaceutical

sciences.2009oct-dec; 1(2):98-105.

Mate GS, Naikwade NS, Chowki CSAA

and Patil SB. Evaluation of anti-nociceptive

activity of Cissus quadrangularis on albino

mice. Int. J. Green Pharm.2008; 2: 118-121.

Bagepalli Srinivas Ashok Kumar , Kuruba

Lakshman , Korala Konta Narsimha

Jayaveera , Devangam Sheshadri Shekar ,

Chinna SwamyVel Muragan , and

Bachappa Mano . Antinociceptive and

Antipyretic Activities of Amaranthus

Viridis Linn in Different Experimental

Models. Avicenna Journal of Medical

Biotechnology. 2009 October-December;

(3):167-171.

Kirtikar KR, Basu BD. Indian Medicinal

Plants. Vol. 3. 2nd ed. In: Kirtikar KR,

Basu BD (eds). Dehra Dun, India:

International book distributors, 1987; 2061-

Council of Scientific and Industrial

Research (CSIR). Publications and

Information Directorate. The Wealth of

India. Vol. 1. A Dictionary of Indian raw

materials and industrial products. New

Delhi, India, 1988; 221.

Agra MF, Baracho GS, Nurit K, Basilio

IJLD, Coelho VPM. Medicinal and

poisonous diversityof the flora of “Cariri

Paraibano” Brazil. J Ethnopharmacol 2007;

(2):283-395.

De Fatima Agra M, Silva KN, Basilio IJLD,

De Freitas PF, Filho JMB. Survey of

medicinal plants used in the region

northeast of Brazil. Braz J Pharmacognosy

; 18(3); 472-508.

Sher H, Khan ZD. Resource utilization for

economic development and folk medicine

among the tribal people. Observation from

Northern part of Pakistan. Pak J Plant

Science 2006; 12(2):149-162.

Quershi SJ, Khan MA, Ahmed M. A survey

of useful medicinal plants of Abbottabad, in

Northern Pakistan. Trakia J Sci 2008;

(4):39-51.

Dar MEI. Ethnobotonical uses of plants of

Lawat district Muzaffarabad Azad Jammu

and Kashmir. Asian J Plant Sci 2003;

(9):680-682.

Arshad M, Khan QUA. Ethnobotonical

study of some medicinal plants of Rawal

Town. Pak J Biol Sci 2000; 3(8):1245-

Muhammad S, Amusa NA. The important

food crops and medicinal plants of northwestern Nigeria. Res J Agric Biol Sci 2005;

(3):254-260.

Patra Arjun , Jha Shivesh , Narasimha

Murthy P, Aher Vaibhav D, Chattopadhyay

Pronobesh , Panigrahi Ghanshyam Roy

Devdeep. Anti-Inflammatory and

Antipyretic Activities of Hygrophila

spinosa T. Anders Leaves (Acanthaceae).

Tropical Journal of Pharmaceutical

Research, April 2009; 8 (2): 133-137.

Sharma PC, Yelne MB, Dennis TJ.

Database on medicinal plants used in

ayurveda. New Delhi, Central Council for

Research in Ayurveda & Siddha.2002, 4,

-331.

Chopra RN, Nayar SL, Chopra IC. Glossary

of Indian Medicinal Plants. New Delhi,

CSIR, 1986, 29.

Nadkarni KM. Indian Materia Medica.

Bombay, India, Popular Prakashan, 1978,

-669.

Mazumder UK, Gupta M, Maiti S,

Mukherjee D. Antitumor activity of

Hygrophila spinosa on Ehrlich ascites

carcinoma and sarcoma- 180 induced mice.

Indian J Exp Biol 1997; 35: 473- 477.

Boily Y, Vanpuyvelde L. Screening of

medicinal plants of Rwanda (Central

Africa) for antimicrobial activity. J

Ethnopharmacol 1986; 16: 1-13.

Fenwick GR, Heaney RK, Mullin WG.

CRC Crit. Rev. Food. Sci., Nut.1983;

,123-30.

Zhao Yuqing. Compound Chinese medicine

prepared by using snake medicine

Qianshouguanyin for preventing cancer of

lung. Faming Zhuanli Shenqing Cong. CN

; 1: 321,509.

Jigam Ali A, Akanya Helmina O,

Emmanuel O. Ogbadoyi, Dauda Bukar EN.

In vivo Antiplasmodial, Analgesic and

Anti-inflammatory Effects of the Root

Extracts of Acacia nilotica Del

(Leguminosae). Asian j. Exp. Biol. Sci,

; 1 (2): 315 – 320.

Borikar VI, Jangde CR, Philip Preety,

Rekhe DS, Atole SK. Study of Antipyretic

Activity of Bauhinia racemosa lam in

Rats.Veterinary World, 2009; 2(6): 217-

Kirtikar KR and Basu BD. Indian Medicinal

Plants. Bishen Singh Mahendra Pal Singh,

Dehradun, India, International book

distributor 1975; Vol.2, 2nd edn: 894- 895.

Vijay Priyanka, Vijayvergia Rekha.

Analgesic, anti-inflammatoryand antipyretic

activity of Cissus quadrangularis. Journal of

Pharmaceutical Science and Technology.

; 2 (1): 111-118.

Prasad GC, Udupa KN. Indian Journal Med.

Res. 1964 ;( 52):480.

Misra SS, Dixit SN. Acta Bot. Ind. 1949 ;(

:147.

Tiwari Varsha, Tiwari Abhishek, Madhavan

V. Preliminary phytochemical analysis,

hptlc studies and antipyretic activity Of

alcohol and aqueous extract of helicteres

isora L .Root. International journal of

pharmacy and pharmaceutical

sciences.2010; 2, (2):74-79.

Kirtikar KR, Basu BD. Indian Medicinal

Plants. Allahabad: Bishan Singh Mahendra

Pal Singh, 1991; 2: 371‐72.

Chopra RN, Nayar SL, Chopra IC. Glossary

of Indian Medicinal plants. New Delhi:

NISCAIR; 2002: 131.

Hallal A , Benali S, Markouk M,

Bekkouche K, Larhsini M, Chait A, et al.

Evaluation of the A nalgesic and

Antipyretic Activities of Chenopodium

ambrosioides L. Asian j. Exp. Biol. Sci.,

; 1(1): 189-192.

Benchaabane A, Abbad, A. Les plantes

medicinales commercialisees a Marrakech.

Collection mainverte, Marrakesh, Morocco.

; 70.

Bellakhdar, J. La pharmacopee marocaine

traditionnelle: Medecine arabe et savoirs

populaires. Editions le Fennec, Ibis Press,

Casablanca, Morocco, 1997; 640.

Garcia-Espinosa R, Chenopodium

ambrosioides L. planta con uso potencial en

el combate de nemetedos fitoparsitos.

Agric. Trop.1980; 2: 92-97.

Verma HK, Baranwal VK. Antiviral

activity and physical properties of the leaf

extract of Chenopodium ambrosioides L. P.

Natl. Acad. Sci., 1983; 92: 461-465.

Dubey NK and Kishore N. Fungitoxicity of

some higher plants and synergistic activity

of their oils. Trop. Sci. 1987 ;( 27): 23-27.

Ruffa M J, Ferraro G, Wagner M L,

Calcagno M L, Campos R L. and Cavallaro

L. Cytotoxic effect of argentine medicinal

plant extracts on human hepatocellular

carcinoma cell. J. Ethnopharmacol. 2002;

: 335-339.

Jain N, Alam M S, Kamil M, Ilyas M,

Niwa M and Sakae A. Two flavonol

glycosides from Chenopodium

ambrosioides. Phytochem. 1990; (29):

-3991.

Gupta M, Mazumder UK, Sambath Kumar

R, Gmathi P, Rajeshwar Y,Kalkoti BB, et

al.anti-inflammatory, analgesic and

antipyretic effects of methanol extract from

Bauhinia racemosa stem bark in animal

models. J Ethnopharmacol.2005; 98(3):

-273.

Sudhakar M , Rao Ch V, Rao P M, Raju D

B. Evaluation of antimicrobial activity of

Cleome viscosa. Fitoterapia 2006; 77: 47–

Yaniv Z, Dafni A, Friedman J, Palevitch D.

J Ethnopharmacol. 1987; 19:145.

Sudhakar M , Rao Ch V, Rao P M, Raju D

B. Evaluation of antimicrobial activity of

Gmelina asiatica. Fitoterapia 2006; 77: 47–

Ismail TS, Gopalakrishnan S, Hazeena BV.

Indian J Pharmacol. 1997; 29:306.

Kirtikar KR, Basu BD, An ICS. Indian

medicinal plants. Dehradun: Bichen Sigh

Mahendra Pal Singh, 1984; 2(2): 1273.

Pendota S C, Yakubu M T, Grierson D S

and Afolayan A J. Anti-inflammatory,

analgesic and antipyretic activities of the

aqueous extract of Hippobromus

pauciflorus Radlk leaves in male Wistar

rats. African Journal of Biotechnology.

May 18; 8 (10):2036-2041.

Clarkson C, Vinesh JM, Neil RC, Olwen

MG, Pamisha P, Motlalepula GM, et al. In

vitro- antiplasmodialactivity of medicinal

plants native to ornaturalised in South

Africa. J. Ethnopharmacol. 2004; 92: 177-

Pendota SC, Grierson DS, Afolayan AJ. An

ethnobotanical studyof plants used for the

treatment of eye infections in the Eastern

Cape Province, South Africa. Pak. J. Biol.

Sci. 2008; 2051-2053.

Neha S, Ranvir GD and Jangade CR.

Analgesic and antipyretic activities of

Curcuma longa rhizome extracts in Wister

Rats. Veterinary World.2009 Aug;

(8):304-306.

Kirtikar KR and Basu B D. Indian

medicinal plants. Periodical Experts Books

Agency, Delhi, 1935; 4(2) 2423-36.

Mutalik S, Paridhavi k, Mallikarjuna Rao C,

Udupa N. Antipyretic and analgesic effect

of leaves of solanum Melongena linn. In

rodents indian journal of pharmacology.

; 35: 312-315.

Warrier PK, Nambiar VPK, Rammanakutty

C. Indian Medicinal Plants. Madras (India):

Orient Longman Publishers Limited; 1996.

Sudheesh S, Sandhya C, Koshy SA, and

Vijayalakshmi NR. Antioxidant activity of

flavonoids from Solanummelongena.

Phytother Res. 1999; 13:393-6.

Noda Y, Kaneyuke T, Igarashi K, Mori A,

Packer L. Antioxidant activity of nasunin,

an anthocyanin in egg plant. Res Commn

Med Pathol Pharamacol 1998: 102; 175-87.

Sudheesh S, Kumar P, Kumar V,

Vijayalakashmi NR. Hypolipidemic effect

of flavonoids from Solanum melongena.

Plant Food Human Nutr. 1997; 51:321-30.

Nanda B K, Jena J, Rath B, Behera BR.

Analgesic and Antipyretic activity of whole

parts of Sphaeranthus indicus Linn. Journal

of chemical and pharmaceutical

research.2009; 1(1): 207-212.

Nadkarni A K. Indian Materia Medica.

Popular Prakashan, Mumbai. 2002;

(1):1162-1163.

Anonymous. Wealth of India, 1st 2005

reprint, National Institute of Science

Communication and Information resources,

CSIR, New Delhi, 2005; 4-5.

Hajare S W, Chandra Suresh, Tandan S K,

Sarma J, Lal J, Telang A G. Analgesic and

antipyretic activities of dalbergia sissoo

leaves. Indian journal of pharmacology

; 32: 357-360.

Kirtikar KR, Basu BD. Indian Medicinal

Plants 2nd ed. Vol.1 Lalit Mohan Basu, 49-

Leader Road, Allahabad, 1933; 818-9.

Nadkarni KM. Indian Materia Medica, 3rd

ed. Vol. 1. Bombay, Popular Book Depot,

; 432.

Chopra RN, Nayer SL, Chopra IC. Glossary

of Indian Medicinal Plants, New Delhi,

CSIR, 1956; 90-91.

Qadrie Zulfkar Latief, Hawisa Najat Tayeb,

Khan Mohd.Wajid Ali, Samuel Moses and

Anandan R. Antinociceptive and antipyretic activity of benincasa hispida

(thunb.) Cogn. In wistar albino rats pak. J.

Pharm. Sci. 2009 july; 22, (3) 287-290.

Nadkarni’s. Indian Materia Medica. 1995;

: 185-186.

Kirtikar and Basu. Indian Medicinal

Plants1985; 2: 1127-1128.

Kirthikar KR, Basu BD. Indian Medicinal

Plants, Vol III, De-hradun, Bishen

Mahendra Pal Singh, 1975; 1915- 1917.

Mukherjee T. Antimalarial herbal drugs. A

review. Fitoterapia. 1991; 62: 197-204.

Forestieri AM, Monforte MT, Ragusa S,

Trovato A, Iauk L. Anti-inflammatory,

analgesic and antipyretic activity in rodents

of plant extracts used in African Medicine,

Phytother Res. 1996; 10: 100-106.

Somchit M N, Nor Shahida A R. and Nur

Shukriyah M H. Anti-Pyretic And

Analgesic Activities of Zingiber Zerumbet

Extracts.Proceeding of the symposium on

environment and natural resources 10-11th

april; hotel renaissance kuala lumpur,

Malaysia vol 1:692-697.

Jaganath I.B. and Ng L.T. Herbs: The green

pharmacy of Malaysia.Vinpress Sdn. Bhd.

and Malaysian Agricultural Research and

Development Institute2000:95-99.

Mascolo N, Jain R and Jain S C, Capasso F

J. Ethnopharmacol, 1989; 27:129-140.

Agrawal AK, Rao CV, Sairam K and Joshi

VK. Indian J Exp Biol. 2000; 38(10):994-

Nakatani N. Biofactors 2000; 13: 141-146.

Bhaskar VH, Balakrishnan N. Analgesic,

anti-inflammatory and antipyretic activities

of Pergularia daemia and Carissa carandas.

Daru; 17(3) 2009.

Kirtikar KR, Basu BD. Indian Medicinal

Plants, vol.III. International Book

Distributors, Dehardun; 1999. 1616-1617 &

-1548.

Nadkarani Ak. Indian Materia Medica,vol.I.

Popular Prakashan Pvt Ltd, Bombay; 1976.

& 277-278.

Anonymous. Indian Medicinal Plants (a

compendium of 500 species), vol.IV. Orient

Longman Ltd, Hyderabad; 1995. 236 -238

& 386 -389.

Wahi AK, Ravi J, Hemalatha S, Singh PN.

Anti diabetic activity of Daemia extens.

Journal of Natural Remedies. 2002; 2(1):

-83.

Khare CP. Indian Medicinal Plants (An

Illustrated Dictionary). Springer Science

and Business Media, New York; 2007. 472

& 123.

Khan Alam, Baki Md. Abdullahil, Abdul

Alim Al-Bari M., Hasan Sohel, Ekramul

Haque M et al.Antipyretic Activity of Roots

of Laportea crenulata Gaud in Rabbit

.Research Journal of Medicine and Medical

Sciences.2007; 2(2): 58-61.

Bhattacharya S. Chrinjib Banoushadi. 3rd

ed., Vol. 2, Anand Publishing Ltd.,

Calcutta-9, 1990; 236-237.

Kirtikar K R and Basu B D. Indian

Medicinal Plants. 2nd ed., Vol. 3, Delhi,

India, 1993; 2343.

Hasan A and Haque A M. Amadar

Bonoohshodi Sompod. 1st ed., Hasan book

house, Dhaka, Bangladesh, 1993; 59.

Obertreis B, Giller K, Teucher T, Behnke B

and Schmitz H. Antiinflammatory effect of

Urtica dioica extract in comparison to

caffeic malic acid. Arzneimittelforschung,

; 46: 52-56.

Harput U S, Saracoglu I and Ogihara Y.

Stimulation of lymphocyte proliferation and

inhibition of nitric oxide production by

aqueous Urtica dioica extract. Phytotherapy

Research, 2005; 19: 346-348.

El –Sadek S E, EL-Gendy A M, Tohamy M

A, Abd El-Aa M. A. Anti-inflammatory,

antipyretic and analgesic effect of Achillea

millefolium and Salix plants. Bs. Vet. Med.

J. January 2007; 17(1):86-92.

Chandler R F, Hooper S N, Hooper D L,

Jamieson D W and Flinn C G. Herbal

remedies of the maritime Indian: sterols and

triterpenes of Achillea millefolium L

(Yarrow). J. Pharm. Sci., 1982; 7(1): 690-

Krivoy N, Pavlotzky E, Chrubasik S,

Eisenberg E and Brook G. Effect of salices

cortex extract on human platelet

aggregation. Planta Medica. 2001; 67 (3):

- 212.

Khonsung Parirat, Nantsupawat Saranyapin,

Jesadanont Sukanya Nimmannit, Vanida,

Chantharateptawan Ampai Panthong. Antiinflammatory and Analgesic Activities of

Water Extract of Malvastrum

coromandelianum (L.) Garcke Thai J

Pharmacol. 2006; 28 (3):8-14.

Kirtikar KR, Basu BD. In: Indian medicinal

plants I. Dehra Dun, India: International

Book Distributors and Publishers, Dehra

Dun, India. 1995; 304.

Anonymous. In: Dictionary of Indian

medicinal plants. Lucknow, India, CIMAP.

; 287.

Fyson PF. The flora of the Nilgiris and

Pulney Hill Tops, Volume I. 1st ed. Dehra

Dun, India: Bishen singh Mahendra Pal

Singh, 1974:43.

Sebastian MK, Bhandari MM. J

Ethnopharmacol. 1984; 122:223. Reddy

YS, Venkatesh S, Suresh B.

Antinociceptive activity of Malvastrum

coromandelinum. Fitoterapi. 2001;

(3):278-8.

Niazi Junaid, Gupta Vikas, Chakarborty

Prithviraj, Kumar Pawan. Antiinflammatory and antipyretic activity of

aleuritis moluccana leaves. Asian Journal of

Pharmaceutical and Clinical Research. 2010

January-March; 3(1):35-37.

Duke JA. Handbook of medicinal herbs.

CRC Press (USA). 1991; 29-30.

Meyre Silva C, Mora TC, Soares Santos A,

Dal Magro J, Yunes RA, Delle Monache F,

et al. A Triterpene and flavonoid C-glyco

side from aleurites moluccana L. Willd.

(euphorbiaceae). Acta Farm. Bom. 1997;

: 169-172.

Meyre Silva C, Mora TC, Soares Santos A,

Dal Magro J, Yunes RA, Biavatti MW, et

al. Preliminary phytochemical and

pharmacological studies of aleurites

moluccana leaves [L] Willd. Phytomed.

; 5: 109-113.

Kaaiakamanu DM, Akina JK. Hawaiian

herbs of medicinal value. Charles E. Tuttle

Company (Vermont); 1922.

Elvitch CR, Manner HI. Aleurites

moluccana. Species profiles for pacific

island agroforestry 2006; 1-16.

Akuodor G C, Idris-Usman M S, Mbah, C

C, Megwas U A, Akpan, J L, Ugwu T C et

al. Studies on anti-ulcer, analgesic and

antipyretic properties of the ethanolic leaf

extract of Gongronema latifolium in

rodents. African Journal of

Biotechnology.2010 March 15; 9 (5): 2316-

Nwinyi OC, Chinedu HS, Ajani OO.

Evaluation of antibacterial activity of

Psidium guajava and Gongronema

latifolium. J. Med. Plant Res. 2008; 2 (8):

-192.

Archana P, Tandan S K, Chandra S and Lal

J. Antipyretic and Analgesic Activities of

Caesalpinia bonducella Seed Kernel

Extract. Phytother. Res. 2005; 19: 376-381.

Chakrabarti S , Biswas Tuhin Kanti, Tapan

Seal, Begum Rokeya, Liaquat Ali ,

AzadKhan A K et al. Antidiabeticactivity of

Caesalpinia bonducella F. in chronic type 2

diabetic model in Long Evans rats and

evaluation of insulin secretagogue property

of its fractions on isolated islets. Journal of

Ethnopharmacology. 2005; 97: 117–122.

Shukla S, Mehta A, Mehta P, Vyas S P,

Shukla S, Bajpai VK. Studies on antiinflammatory,antipyretic and analgesic

properties of Caesalpinia bonducella F. seed

oil in experimental animal models. Food

and Chemical Toxicology. 2009.

Shukla S, Mehta A, John J, Singh S, Mehta

P, Vyas SP. Antioxidant activity and total

phenolic content of ethanolic extract of

Caesalpinia bonducella seeds. Food and

Chemical Toxicology. 2009; 47: 1848-

Adeolu A, Adedapo, Margaret O,

Sofidiya, Viola Maphosa, Busani Moyo ET

AL.Anti-inflammatory and analgesic

activities of the aqueous extract of Cussonia

paniculata stem Bark. Rec. Nat. Prod.

; 2:2 46-53.

Hutchings A, Scott A H, Lewis G. Zulu

medicinal plants: An inventory, Natal,

South Africa: University of Natal Press.

; 266-267.

Tetyana P and Van Staden J.

Micropropagation of Cussonia paniculata-a

medicinal plant with horticultural potential.

S Afr J Bot. 2001; 68: 51-54.

Afolayan A J and Adebola P O. In vitro

propagation: A biotechnological tool

capable of solving the problem of medicinal

plants decimation in South Africa. Afr J

Biotech. 2004; 3: 683-687.

Igbe Ighodaro, Ozolua Raymond I, Okpo

Steve O and Obasuyi Osahon. Antipyretic

and Analgesic Effects of the Aqueous

Extract of the Fruit Pulp of Hunteria

umbellata K Schum (Apocynaceae).

Tropical Journal of Pharmaceutical

Research. August 2009; 8 (4): 331-336.

Raman A, Mallam V. Enhanced in vitro

activity of glucokinase enzyme in the

Presence of Hunteria umbellata seeds, a

traditional Nigerian treatment for diabetes. J

Pharm Pharmacol. 1994; 46: 1046.

Elujoba AA. Female infertility in the Lands

of traditional birth attendants in SouthWestern Nigeria. Fitoterapia. 1995; 66:

-248.

Raquibul Hasan S M, Jamila Mariam,

Majumder Muntasir Mamun. Analgesic and

Antioxidant Activity of the

Hydromethanolic Extract of Mikania

scandens (L.) Willd. Leaves. American

Journal of Pharmacology and Toxicology.

; 4 (1): 1-7.

Ysrael M C and Croft K.D. Inhibition of

leukotriene and platelet activating factor

Synthesis in leucocytes by the sesquiterpene

lactone scandenolide. Planta Med. 1990; 56:

-270.

Bishayee A and Chatterjee M.Protective

effects of Mikania cordata root extract

against Physical and chemical factorsinduced gastric erosions in experimental

animals. Plants Med. 1994; 60: 110-113.

DOI: 10.1055/s-2006-959428

Bishayee A and Chatterjee M.

Anticarcinogenic biological response of

Mikania cordata: Refections in hepatic

biotransformation systems. Cancer Lett.

; 81: 193-200. DOI: 10.1016/0304-

(94)90202-X

Mosaddik, M A and Alam K M. The

antiulcerogenic effect of an alkaloidal

fraction From Mikania cordata on

diclofenac sodium-induced gastrointestinal

lesions in rats. J. Pharm. Pharmacol.2000;

: 1157-1162. DOI:

1211/0022357001774930

Paschapur Mahesh S, Patil Swati, Patil

Sachin R, Kumar Ravi, Patil M B.

Evaluation Of the analgesic and antipyretic

activities of Ethanolic extract of male

flowers (inflorescences) of borassus

Flabellifer l. (arecaceae). International

journal of pharmacy and pharmaceutical

sciences.2009; Oct-Dec.1 (2):98-105.

Kapoor LD. Handbook of Ayurvedic

medicinal plants: Herbal reference library.

CRC Press. Florida; 2000: 82.

Vaidyaratnam PS. Varier’s Arya Vaidya

Sala -Indian Medicinal Plants A

Compendium of 500 species, Orient

Longman. India; 1994 (Reprint 2002),

:293-296.

Chander Ramesh, Singh Kavita, Khanna A

K, Kaul S M , Puri Anju, Saxena Rashmi et

al.J Antidyslipidemic And Antioxidant

Activities Of Different Fractions Of

Terminalia Arjuna Stem Bark.Indian

Journal Of Clinical Biochemistry. 2004; 19

(2): 141-148.

Tiwari AK, Gode J D Dubey G P. Effect of

Terminalia arjuna on lipid profiles of

rabbits fed hypercholesterolemic diet. Int. J.

Crude Drug Res. 1990; 28: 43-47.

Khanna A K, Chander R Kapoor N J.

Terminalia arjuna an Ayurvedic cardiotonic

regulates lipid metabolism in hyperlipaemic

rats. Phytotherapy Res. 1996; 10: 663-

N

Shaila H P, Udupa S L, Udupa A L, Nair

N S. Effect of Terminalia arjuna on

experimental hyperlipidemia in rabbits. Int.

J. Pharmacol. 1997; 35: 1-4.

Gauthaman K, Maulik M, Kumari R,

Manchandra S C, Dinda A K and S K

Maulik. Effect of chronic treatment with

bark of Terminalia arjuna a study in isolated

Ischemicreperfused rat heart. J.

Ethnopharmacol 2001; 75:197-201.

Kandil F E and Soliman A M. A new tannin

anticancer promotor from Terminalia

arjuna. 2nd International Electronic

Conference on Synthetic Organic Chemistry

(ECSOC-2), 1998; Sept, 1-30.

Kaur K, Arora S , Kumar S and Nagpal

A. Antimutagenic activities of acetone and

methanol fractions of Terminalia arjuna.

Food Chem. Toxicol. 2002; 40: 1475-1482.

Andrews RC, Rooyckers O, Walker BR.

Effects of the 11 beta –hydroxysteroid

dehydrogenase inhibitor carbenoxolone on

insulin sensitivity in men with type 2

diabetes. J Clin endocrinol metab.

;88(1):285-291.

Kokate C K. Pharmacognosy, 12th ed. Nirali

publication; 180.

Hasan A F, Begum S, Furumoto T, Fukui

H. Bioscience BiotechnologyBiochemistry.

; 64: 4: 873- 874.

Shahidi F, Chandrika M, Liyana-Pathirana

Dana S W. FoodChemistry. 2006; 99: 3:

-483.

Wang Bor-Sen, Chang Lee-Wen, YenWenJye, Duh Pin- Der. FoodChemistry. 2007;

: 1: 351-360.

Hu Y M, Wang H, Ye W C, Zhao S X. J

Chinese MateriaMedica. 2007; 32(7): 603-

C P Khare. Indian medicinal plants. An

lllustrated dictionary. Springer science,

; 670.

Biswdev bishayi, subhashree

roychowdhury, soumya ghosh, mahuya

sengupta. Hepatoprotective and

immunomodulatory properties of Tinospora

cordifolia in CCl4 Intoxicated mature

albino rats. Journal of toxicological sciences

; 27(3) 139-146.

Singh SS, Pandey SC, Srivastava S, Gupta

VS, Patro B, Ghosh AC. Chemistry and

medicinal properties of tinospora cordifolia

(guduchi). Indian journal of pharmacology.

; 35: 83-91.

Misra B, Bhava prakash nighantu, vol.1,

(Hindi commentary by K C Chunekar),

(Chowkhamba Vidya bhavan, Varanasi),

; 269.

Cui MF. Observation of curative effect of

Jin Gang Ten syrup on one hundred and

twenties patients suffer from pelvic

inflammatory. Modern Journal of

IntegratedTraditional Chinese and Western

Medicine. 2001; 6: 515.

He YL. Reports on join‐curing eight

patients suffer from chronic pelvic

inflammatory By using Jin Gang Ten

capsule and shortwave. Chinese Space

Medicine Journal. 2002; 1: 70.

Zheng JZ. Clinical summary of one hundred

patients suffer from pelvic inflammatory

Cured with Jin Gang Ten syrup. Guang

Dong Medicine. 1996; 5: 330–331.Oct

Qiu RQ. Clinical analysis on curing thirties

patients suffer from chronic pelvic

Inflammatory with bump by using

compounds containing Smilax china L.

Journal of Fu jian College of Traditional

Chinese Medicine. 1997; 4: 4–5.

Huang ZQ, Huang YR. Clinical application

of single Smilax china L. on prolong life of

the patients suffer from liver neoplasms.

Chinese National Folk Medicine Journal.

; 45: 212–213.

C. P. Khare. Indian medicinal plants. An

lllustrated dictionary. Springer science,

; 79.

Chaurasia Savita. Anti-inflammatory and

Antioxidant Activity of Strychnos nux

vomica Linn. American-Euras ian Journal

of Sus tainable Agriculture. 2009; 3(2):

-252.

Warrier P K, Nambiar V P K and

Ramankully C. In Indian Medicinal Plants,

a Compendium of 500 species. Orient

Longman Ltd., Madras, India, 1996; 5: 202-

Jain S K and R A. DeFilipps, In Med ic in a

l Plants of India. Reference Publications,

Algonac, Michigun, 1991; 1: 392-393.

Shukla K P, S P Singh, Kishore N. Singh D

R and Srivastava S. Evaluation of rasnadi

guggulu compound in the treatment of

rheumatoid arthritis. Rheumatism 1985. 21:

-25.

Advankar M K & Chitnis M P. In vitro

anticancer activity of RC-18.

Chemotherapy. 1982; 28:291.

Singh D C & Ojha J K. Primary study of

effect of manjistha and kanchnara on

diabetic microangiopathy with special

reference to diabetic leg ulcer. Sachitra

ayurveda . 1991; 44: 126.

Mhaskar K S, Blatter E & Caius J F. Indian

medicinal plants – their usage in ayurveda

and unani medicine. 2000; 3.

Mooradian A D. diabetic complication of

central nervous system, endocri rev. 1988;

: 346.

Kasture V S, Deshmukh V K, Chopde C T,

Anticonvulsant and behavioral actions of

triterpene isolated from rubia cordifolia.

Indian J Exp. Biol; 2000:38:675.

Kasture S B, Kasture V S, Chopde C T.

Anti-inflammatory activity of Rubia

cordifolia roots. J Nat rem.2001; 1: 111.

K hare C P. indian medicinal plants. An

lllustrated dictionary. springer

science.2007; 238-239.

Ganju L, Karan D, Chanda S, Srivastava

KK, Sawhney RC, Selvammurthy W.

Immunomodulatory effects of agents of

plant origin. Biomed pharmacother. 2003;

(7): 296-300.

Gupta GL, Rana AC. Withania somnifera

(Ashwagandha). A Review. Phcog Rev.

; 1: 129–136.

Ravishanker B, Bhaskaran NR, and

Sasikala CK. Pharmacological evaluation of

vitex negundo leaves. Bull Medico EthnoBot Res. 1985; 6(1):72-92.

Telang RS, Chatterjee S and Varshneya C.

Studies on Analgesic and anti-Inflammatory

activities of Vitex negundo Linn. Indian J

Pharmacol. 1999; 31(5): 363-366.

Vishal R Tandon. Medicinal uses and

biological activities of Vitex negundo.

Natural product radiance.2005; 4(3):162-

Khosla P, Sangeeta Bhanwra, Singh J,

Srivastava R K. Antinociceptive activity of

Azadirachta Indica (Neem) in Rats. Indian

journal of pharmacology 2000; 32: 372-

Kaushik Biswas, chattopadhyay ishita,

Banerjee Ranjit K and bandhopadhyay

Uday . Biological activities and medicinal

properties of neem (Azadirachta indica).

Current sci .2002; 82(11): 1336-1345.

Araujo CAC, Leon LL. Biological activities

of curcuma longa L. Mem lnst oswaldo

cruz. Rio de janeiro. 2001; 96(5):723-728.

Jain sanjay, shrivastava satyaendra, nayak

satish, sumbhate S. Recent trends in

Curcuma longa Linn. Pharmacognosy

reviews. 2007;1(1): 119-128.

Goyal BM, Bansal P, Gupta V, Kumar S,

Singh R, Maithani M. Pharmacological

Potential of Boerhaavia diffusa: An

Overview.International Journal of

Pharmaceutical Sciences and Drug

Research. 2010; 2(1): 17-22

Sen T, Dhara AK, Bhattacharjee pal S and

Chaundhuri NAK. Antioxidant activity of

Methanol fraction of Pluchea indica root

extract.Phyto Res.2002; 16:331-335.

Forest R, D. J R Soc Med 1982; 75:268.

Kalaivani T and Mathew Lazar.

Phytochemistry and Free radical scavenging

activities Of Oroxylum indicum. Environ.

We Int. J. Sci. Tech. 2009; 4:45-52.

Khan mohib and Siddiqui Mustafa.

Antimicrobial activity of Piper

fruits.Natural productradiance. 2007; 6(2):

-113.

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30-09-2010

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Mukesh Kumar Singh, Kushagra Nagori, D.K Tripathi. Potential Analgesic & Anti-Pyretic Herbal drugs: A Comparative Review of Marketed Products. ijp [Internet]. 2010 Sep. 30 [cited 2024 Dec. 23];2(3):197-209. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/38

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