Herbal Plants: A Potential Agent to Cure Infectious Mastitis in Bovine Animals
Keywords:
Antibacterial activity, Clinical mastitis, Medicinal Plants, Subclinical mastitisAbstract
The medicinal plants are used in traditional treatments in order to cure variety of diseases since prehistoric period. Bovine mastitis is an inflammation of mammary gland and it is the most serious and economically important disease in the dairy milk production worldwide. The main aim of this study was to identify such plants with antimicrobial efficacy against some mastitis pathogens. For this purpose the locally available plants viz., Gymnema sylvestre, Holarrhena antidysenterica, Vernonia anthelmintica Enicostemma littorale, Momordica charantia, Swertia chirata, Azadirachta indica, Caesalpinia bonducella were selected for the study. These plants were screened against 18 bacteria that were isolated from clinical and sub clinical milk samples of buffaloes. The plants were extracted using methanol and showed the inhibitory effect against gram- positive and gram-negative bacteria. But gram-positive bacteria are more sensitive than gram-negative bacteria. The largest zone of inhibition [24mm in diameter] was recorded against corynebacterium xerosis with the leaf extract of Azadirchta indica. It was concluded that these plant extract can be used as a drug against the mastitis causing pathogens.
References
Farnsworth NR, Soejarto DD. Global Importance of Medicinal Plants.In: Akerle O, Heywood V, Synge H [eds.] Conservation of Medicinal Plants. 1991. Cambridge University Press,Cambridge.
Attisso MA. Phytopharmacology and Phytotherapy. In: Bannerman RH, Burton J, [eds.], Traditional Medicine and Health Care Coverage. 1983. World Health Organization,Geneva.
Devi K, Karthikai GD, Thirumaran G, Arumugam R, Anantharaman P. Antibacterial activity of selected medicinal plants from Parangipettai coastal regions; Southeast coast of India. World App Sci J. 2009;7[9]:1212–1215.
Girish HV, S Satish. Antibacterial activity of important medicinal plants on human pathogenic bacteria-a comparative analysis. World App Sci J. 2008;5[3]:267–271.
Clardy J, Walsh C. Lessons from natural molecules. Nature 2004;432:829-837.
Verpoorte R, Choi YH, Kim HK. Ethanopharmacology and system biology: a perfect holistic match. J Ethnopharmacol 2005;100: 53-56.
Mitscher LA, Drake S, Gollapudi SR et al. A modern look at folkloric use of anti-infective agents. J Nat Prod 1987;50: 1025-1040.
Palombo EA, Semple SJ. Antibacterial activity of traditional Australian medicinal plants. J Ethnopharmacol 2001;77: 151-157.
Zgoda-Pols JR, Freyer AJ, Killner LB et al. Antimicrobial resveratrol tetramers from the stem bark of Vatica oblongifolia ssp. oblongifolia . J Nat Prod 65: 1554-1559, 2002.
Parekh J, Jadeja D, Chands S. Efficacy of aqueous and methanol extracts of some medicinal plants for potential antibacterial activity. Turk J Biol 2005;29: 203-210.
Nair R, Chanda S. Antibacterial activity of some medicinal plants against some medically important bacterial strains. Indian J Pharmacol 2006;38: 142-144.
Parekh J, Chands S. I n v i t r o antimicrobial activity and phytochemical analysis of some Indian medicinal plants. Turk J Biol 2007a;31: 53-58.
Parekh J, Chands S. In vitro antibacterial activity of some aqueous and alcoholic extracts of various Indian plant species against selected pathogens from Enterobacteriaceae. Afr J Microbiol Res 2007b;1: 92-99.
Bartner A. and Grein E. Antibacterial activity of plant extracts used externally in traditional medicine. Journal of Ethnopharmacology, 1994;44:35-40.
Ruegg, P. L. Treatment of Clinical Mastitis University of Wisconsin, 2011;Madisonhttp://milkquality.wisc.edu/wpconten t/uploads/2011/09/treatment_of_clini cal_mastitim.pdf
Angela, H. A. M., Mevius, D., Guerra, B., Mullany, P ., Roberts, A. P. & Aarts, H. J. M. Acquired Antibiotic Resistance Genes: An Overview. Front Microbiol 2011;2: 203.
Vaibhav DB, Bhavyata BP, Chaitanya GJ, and Anju PK. Curcuma longa: An alternative to antibiotics to combat mastits in cattle.Wayamba Journal of Animal Science.2013; P582-P589.
Rahman MS, Begum J, Chowdhury JU and Anwar MN. Antimicrobial activity of Holarrhena antidysenterica against Salmonella typhi. The Chittagong University Journal of Science.1998; 22[1]: 111-112.
Rojas A, Hernandez L, Pereda-Miranda R, and Mata R. Screening for antimicrobial activity of crude drug extracts and pure natural products from Mexican medicinal plants. Journal of Ethnopharmacology, 1992;35: 275-283.
Cowan MM. Plant Products as Antimicrobial Agents. Clin. Microbiol. Rev.1999; 12[4]: 564-582.
Louisiane FVB, Jacks PP, Rosendo AY, Jacir DM, Franco DM, De Campos F, De Souza MM, Valdir C-F. Pharmacological and phytochemical evaluation of adiantum cuneatum growing in Brazil. Z. Naturforsch C.2003; 58[3-4]: 191-194.
Rasadah MA, Houghton PJ. Antimicrobial activity of some species of bignoniaceae. ASEAN Rev. Biodiver. Environ. Conserv.1998; 3: 1-3, article available on http://www.arbec.com.my/pdf/may-3.pdf.
