The Effect of Aqueous Extract of Hibiscus sabdariffa seeds on Hematological Parameters of Anemic Rats
Keywords:
Roselle, medicinal plants, hematology, nutrient supplementsAbstract
The current study was conducted to investigate the effect of the aqueous extract of H. sabdariffa seeds on anemic rats. Anemia was induced in rats by two models, the first model is feeding rats with iron deficient diets for the induction of nutritional anemia while the hemorrhagic anemia model was induced in rats by bleeding off 30 % their blood volume. 400 mg of the extract/kg body weights of rats administered to anemic rats has increased their hematological parameters. This increase was significant in the hemoglobin, PCV and RBC count of hemorrhagic anemic rats and the extract caused significant increase in the hemoglobin level of the nutritionally iron-deficient rats.
References
. Bruno de Benoist, Erin McLean, Ines Egli
and Mary Cogswell. WHO Global
Database on Anemia 2008.
. Al Wandawi H, Al Shaikh K l YK and
Abdul Rahman M, Roselle seed: a new
protein source. Journal of Agricultural and
Food Chemistry 1984; 32: 510-512.
. Bako I G, Mabrouk M A and Abubakar A,
Antioxidant effect of ethanolic seed extract
of Hibiscus sabdariffa linn (Malvaceae )
Alleviate the toxicity induced by chronic
administration of sodium nitrate on some
hematological parameters in Wistars Rats.
Advanced Journal of Food Science and
Technology 2009; 1(1): 39-42.
. Nwaiwu N E, Shelia M and Rauf I A,
Antimicrobial activity of crude extracts of
Moringa oleifera, Hibiscus sabdariffa and
Hibiscus esculentus seeds against some
enterobacteria. Journal of applied
phytotechnology in environmental
sanitation 2012; 1(1): 11-16.
. Stewart E A, Chemical analysis of
ecological materials 1989; 2 th edition.
Blackwell Scientific Publications.
. Trevor P and Ruth R , Handbook on the
care and management of laboratory
animals 1988; Page 320. 6 the edition
Longman Scientific and Technical.
. Agbor AG and Odetola A A,
Hematological studies of Paraqutina
ingrescens on hemorrhagic anemic rats.
African Journal of medicine and Medical
Sciences 2011; 30(1-2): 105-9.
. John L Beard, Joseph W Burton and
Alizabeth C Theil, Purified ferritin and
soybean meal can be sources of Iron for
treating iron deficiency in rats. Human and
clinical nutrition 1996; 126: 154-160.
. Kinsella J E, Sea foods and human health
and diseases. Marcel Dekker 1987; Inc.
New York and Basel.
. Yagoub A G, Mohamed B E, Ahmed A H
And El Tinay AH, Study on furundu, a
traditional Sudanese fermented roselle
(Hibiscus sabdariffa L.) seed: effect on in
vitro protein digestibility, chemical
composition, and functional properties of
the total proteins. J Agric Food Chem.
; 52(20):6143-50.
. Diarra S S, Kwari I D, Girgiri Y A, Saleh B
and Igwebuike J U, The use of sorrel
(Hibiscuss sabdariffa) seed as a feed
ingredient for poultry: A Review. Research
Opinions in Animal and Veterinary
Sciences 2009; (2223-0343
