Preliminary screening of Waltheria indica (L.) plant for its anti-inflammatory activity


  • Amol Chandekar School of Pharmacy & Research, Bhanpur, Bhopal, MP, India 442037
  • Amber Vyas University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur, C.G., India
  • Neeraj Upamanyu School of Pharmacy & Research, Bhanpur, Bhopal, MP, India 442037
  • Atul Tripathi Ph. D. Research Scholar University Institute of Pharmacy Pt. Ravishankar Shukla University Raipur (C.G.) 492 010, INDIA
  • Surendra Agrawal Shobhaben Pratapbhai Patel School of Pharmacy & Technology Management, Mumbai, Maharashtra, India


Anti-inflammatory, Waltheria indica L., Delayed type hypersensitivity


The investigation on anti-inflammatory activity of the various extract of Waltheria indica L. was reported to find out the pharmacological basis for its ethnomedical use. The anti-inflammatory activity of the pet ether (PEW) and methanol (MEW) extracts of the leaves of Waltheria indica L. (Malvaceae)were evaluated by using in vivo (Carrageenan & histamine induced rat paw edema, cotton pellet granuloma test) models. It was observed that, all the extracts showed significant activity in the in-vivo model at the dose of 500 mg/kg b.w. orally, when compared with control and standard drugs. Of the two extracts tested, methanol extract MEW showed most significant activity well in comparison to the standard drug. Therefore, present study suggests, potential of leaves of Waltheria indica L. in both models of acute and chronic inflammation.


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How to Cite

Amol Chandekar, Amber Vyas, Neeraj Upamanyu, Atul Tripathi, Surendra Agrawal. Preliminary screening of Waltheria indica (L.) plant for its anti-inflammatory activity. ijp [Internet]. 2017 Jun. 30 [cited 2024 Jun. 23];9(2):275-8. Available from:



Original Research Articles