A DETAILED OVERVIEW OF MEDICINAL PLANTS HAVING HYPOGLYCEMIC ACTIVITY
Keywords:
diabetes mellitus, glycemic control, medicinal plants, antidiabetic, hypoglycemicAbstract
Diabetes mellitus represents a spectrum of metabolic disorder, which has become one of the major public health concerns worldwide. Diabetes mellitus has emerged as a third leading killer after cancer and cardiovascular/cerebrovascular diseases and India has a distinction of having largest number of diabetics in world second to China. Herbal medicine for treating chronic diseases, especially diabetes has gained an exponential growth in the last few years and both developing and developed countries are adopting herbal drugs for treatment of diabetes mellitus. The World Health Organization (WHO) has listed 21,000 plants, which are used for medicinal purposes around the world. The WHO has defined herbal medicines as finished labelled medicinal products that contain aerial or underground parts of the plants or other plant material or combination thereof as active ingredients, whether in crude state or as plant preparations. This review attempts to present the profiles of plants with hypoglycemic properties, reported in the literature with proper categorization according to the botanical name, family, parts used, chemical constituents, and its other uses. Relevant medical databases and websites were searched. To qualify for inclusion, the herbs should have confirmed hypoglycemic potential. Other criteria for inclusion are: published in English and peer-reviewed journals. We also used related keywords like diabetes mellitus, plant, herb, glycemic control, natural or herbal medicine, Ayurvedic plants, and hypoglycemic plants, as keywords or combination of them. A total of 151 herbs belonging to 72 families were outlined in this review.
References
atel DK, Kumar R, Prasad SK, Sairam K, Hemalatha S. Antidiabetic and in vitro antioxidant potential of Hybanthus enneaspermus (Linn) F. Muell in streptozotocin-induced diabetic rats. Asian Pac J Trop Biomed. 2011; 1(4): 316-322. 2. T.K. Ujwala, Shawn Tomy, Sandra Celine, J. Sam Johnson Udaya Chander. A Systematic Review of Some Potential Anti-Diabetic Herbs Used in India Characterized by its Hypoglycemic Activity. IJPSR. 2015; 6(12) (In Press). 3. Available from: http://www.searo.who.int/EN/Section1243/Section1382/Section1386/Section1898_9438.htm. Last reviewed on 14-11-2015. 4. World Health Organization. Regional Office for South East Asia. Health Situation in South East Asia Region (1998-2000), Regional office for SEAR New Delhi. 2002. Available from: http://www.searo.who.int/LinkFiles/Health_Situation_book.pdf. Last reviewed on 14-11-2015. 5. Shukla R, Sharma SB, Puri D, Prabhu KM, Murthy P S. Medicinal plants for treatment of diabetes mellitus. Indian Journal of Clinical Biochemistry. 2000; 15:169. 6. Saxena A, Vikram NK. Role of selected Indian plants in management of type 2 diabetes: a review. J Altern Complement Med. 2004; 10(2): 369-378. 7. Mutalik S, Sulochana B, Chetana M, Udupa N, Uma Devi UP. Preliminary studies on acute and sub acute toxicity of an antidiabetic herbal preparation, Dianex. Indian Journal of Experimental Biology. 2003;4: 316- 320. 8. Piyush MP, Natvarlal MP, Ramesh KG. Holistic classification of herbal antidiabetics: A review. Pharma Times. 2006; 38: 19-25. 9. Sharma R, Arya V. A Review on Fruits Having Anti-Diabetic Potential. Journal of Chemical and Pharmaceutical Research. 2011; 3(2):204-212. 10. Rao MU, Sreenivasulu M, Chengaiah B, Reddy KJ, Chetty CM. Herbal Medicines for Diabetes Mellitus: A Review. International Journal of PharmTech Research. 2010; 2(3): 1883-1892. 11. Atolani Olubunmi, Olatunji Gabrielademola, Fabiyi Oluwatoyinadenike. Blighia Sapida; The Plant and Its Hypoglycins an overview. Journal of Scientific Research. 2009; 39(2):15-25. 12. K.K. Chen, Robert C. Anderson, Max C Mc Cowen, Paul N. Harris. Pharmacologic action of Hypoglycin A and B. Journal of Pharmacology and Experimental Therapeutics. 1957; 121(3): 272-85. 13. U.A. Deokate, S.S. Khadabadi. Pharmacology and phytochemistry of Coccinia Indica. Pharmacophore. 2012; 3(3): 179-185. 14. Available from: www.pubmedcentral.nih.gov/articlerender.fcgi?artid=113429. Last reviewed on 14-11-2015. 15. S Venkateswaran, L Pari. Effect of Coccinia indica leaves on antioxidant status in streptozotocin-induced diabetic rats. Journal of Ethnopharmacology. 2003; 84(2):163-168. 16. U Farrukh, H Shareef, S Mahmud, SA Ali, GH Rizwani. Antibacterial activities of Coccinia grandis. Pak. Journal of Botany. 2008; 40(3): 1259-62. 17. Archna Sharma, RA Sharma, Hemlata Singh. Phytochemical and Pharmacological Profile of Abutilon Indicum L. Sweet, A Review. International Journal of Pharmaceutical Sciences Review and Research. 2013; 20(1) :120-127. 18. Roshan S, Sadath Ali, Abdullah Khan, Tazneem B, Purohit MG. Wound Healing activity of Abutilon Indicum. Phcog Mag. 2008; 4(15): 85-88. 19. Seetharam YN, Chalageri G, Shetty SR, Bheemachar. Hypoglycemic activity of Abutilon indicum leaf extracts in rats. Fitoterapia. 2002; 73(2):156-159. 20. S Roshan, Ali Sadath, MA Saleem, MJ Patel, Ali Asgar. Effect of Abutilon indicum on carbon tetra chloride induced hepatic damage in albino rats. Jr. Pharmaceutical Research. 2004; 3(4):61-62. 21. T Pullaih. Medicinal Plants in Andhra Pradesh, India. Daya Books, 2002; 1:1-9. 22. MK Bagi, GA Kalyani, TJ Dennis, K Akshaya Kumar, HK Kakrani. A preliminary pharmacological of Abutilon indicum Analgesic activity. Fitoterapia 1985; 56 (3): 169-171. 23. Kokila A, Parmar, Anup N Patel, Sarju N Prajapati, Rakesh I Patel. Anti viral in HeLa cell cultures, antibacterial and antioxidant activity of Acacia arabica seeds extracts by the use of DPPH free radical method. Journal of Chemical and Pharmaceutical Research. 2010; 2(4):324-332. 24. H Gilani, F Shaheen, M Zaman, KH Janbaz, BH Shah, MS Akhtar. Studies on antihypertensive and antispasmodic activities of methanol extract of Acacia nilotica pods. Phytotherapy Research. 1999; 13(8):665–9. 25. Rajbir Singh ,Bikram Singh, Sukhpreet Singh, Neeraj Kumar, Subodh Kumar, Saroj Arora. Anti-free radical activities of kaempferol isolated from Acacia nilotica (L.) Willd. Ex. Del. Toxicology in Vitro. 2008; 22(8):1965-1970. 26. T Pullaih. Medicinal Plants in Andhra Pradesh, India. Daya Books, 2002; 1: 12-6. 27. Gayathri Devi, Anitha John, R Sreekala Devi, VA Prabhakaran. Pharmacognostical Studies On Acacia Catechu Willd And Identification of Antioxidant Principles. International Journal of Pharmacy and Pharmaceutical Sciences. 2011; 3(2): 108-111. 28. D Ray, KH Sharatchandra, IS Thokchom. Antipyretic, antidiarrhoeal, hypoglycaemic and hepatoprotective activities of ethyl acetate extract of Acacia catechu Willd. in albino rats. IJP. 2006; 38(6): 408-413. 29. Jayasekhar P, Mohanan PV, Rathinam K. Hepatoprotective Activity of ethyl acetate extract of Acacia catechu. Indian J Pharmacol. 1997; 29: 426-428. 30. Kusum S Akki, G Krishnamurthy, HS Bhoja Naik. Hepatoprotective And Anti Oxidant Effect Of Actinodaphne Hookeri Meissn. Leaf Extracts Against CCL4- Induced Liver Injury In Rats. Indian.Journal Of Natural Products And Resources. 2014; 5(4): 313-319. 31. DD Prajapati, NM Patel, RV Savadi, KS Akki, K Mruthunjaya. Alleviation of alloxan- induced diabetes and its complications in rats by Actinodaphne hookeri leaf extract. Bangladesh Journal of Pharmacology. 2008; 3:102-106. 32. G Brahmachari, S Mondal, D Chatterjee and AK Bramachari. Phytochemical and biological activities of adiantum species. Journal of Scientific and Industrial Research. 2003; 62: 1119-1130. 33. T Pullaiah. Encyclopaedia of world medicinal plants. Regency Publications, New Delhi. 2006; 1: 63. 34. Shaikh J, Uddin, Darren Grice, Evelin Tiralongo. Cytotoxic effects of Bangladesh Medicinal plant extracts. Evidence-Based Complementary and Alternative Medicine. 2009; 2011:1-7. 35. Ganesh N Sharma, Susheel K Dubey, Piush Sharma, Nitin Sati. Medicinal Values of Bael (Aegle marmelos) (L.) Cor: A Review. International Journal of Current Pharmaceutical Review and Research. 2011; 1(3): 12-22. 36. Vinodhini Singanan, Malairajan Singanan, Hazeena Begum. The Hepatoprotective Effect of Bael Leaves (Aegle Marmelos) in Alcohol Induced Liver Injury in Albino Rats. International Journal of Science and Technology. 2007; 2(2):83-92. 37. CP Khare. Indian Medicinal Plants: An Illustrated dictionary. Springer Science. 2007; 88: 21-22. 38. Rajesh Arora, Damodar Gupta, Raman Chawla, Ravinder Sagar, Ashok Sharma, Raj Kumar. Radioprotection by Plant Products: Present Status and Future Prospects. Phytotherapy Research. 2005; 19:1–22. 39. Sharrif Moghaddasi M, Sandeep Kumar Verma. Aloevera their chemicals composition and applications: A review. Int J Biol Med Res. 2011; 2(1): 466-71. 40. Amar Surjushe, Resham Vasani, DG Saple. Aloevera: A Short review. Indian journal of dermatology. 2008; 53(4):163-166. 41. Arshad Hussain, MD Parwez Ahmad, Shadma Wahab, MD Sarfaraj Hussain, Maksood Ali. A review on pharmacological and phytochemical profile of Aspatarus racemosus willd. Pharmacology Online. 2011; 3:1353-1364. 42. Alka Agrawal, Meenakshi Sharma, Santosh Kumar Rai, Bharat Singh, Manisha Tiwari, Ramesh Chandra. The effect of the aqueous extract of the roots of Asparagus racemosus on hepatocarcinogenesis initiated by diethylnitrosamine. Phytotherapy Research. 2008; 22(9):1175-1182. 43. Siddiqui BS, Afshan F, Gulzar T, Hanif M. Tetracyclic triterpenoids from the leaves of Azadirachta indica. Phytochemistry. 2004; 65(16): 2363-2367. 44. Biswas Kaushik, Ishita Chattopadhyay, Ranjit K Banerjee, Uday Bandhopadhyay. Biological activities and medicinal properties of neem (Azadirachta indica). Current Sci (India) 2002; 82(11):1336-1345. 45. Mazumder Papiyamitra, Dassaumya, Dassanjita, Dasmanas Kumar. Phyto Pharmacology of beriberi saristata: A review. Journal of drug delivery & Therapeutics. 2011; 1(2): 46-50. 46. BM Goyal, P Bansal, V Gupta, S Kumar, R Singh, M Maithani. Pharmacological Potential of Boerhaavia diffusa: An Overview. International Journal of Pharmaceutical Sciences and Drug Research. 2010; 2(1):17-22. 47. AKS Rawat, S Mehrotra, SC Tripathi, U Shome. Hepatoprotective activity of Boerhaavia diffusa L. roots—a popular Indian ethnomedicine. Journal of Ethnopharmacology. 1997; 56(1):61-6. 48. CA Hiruma-Lima, JS Gracioso, EJB Bighetti, L Germonsén Robineou, ARM Souza Brito. The juice of fresh leaves of Boerhaavia diffusa L. (Nyctaginaceae) markedly reduces pain in mice. Journal of Ethnopharmacology. 2000; 71(1-2):267-74. 49. L Pariand, M Amarnath Satheesh. Anti diabetic activity of Boerhaavia diffusa L.: Effect on hepatic key enzymes in experimental diabetes. Journal of Ethnopharmacology. 2004; 91(1): 109-113. 50. Komal Moon, SS Khadabadi, UA Deokate, SL Deore. Caesalpinia bonducella F- An Overview. Report and Opinion. 2010; 2(3): 83-90. 51. Gupta SS, Verma SC, Garg VP, Khandelwal P. Studies on antidiabetic effects of Casearia esculanta. Indian Journal of Med. Research. 1967; 55(7):754-763. 52. Bhalerao SA, Kelar TS. Traditional Medicinal Uses, Phytochemical Profile and Pharmacological Activities of Cassia fistula Linn. International Research Journal of Biological Sciences. 2012; 1(5): 79-84. 53. Mohd. Danish, Pradeep Singh, Garima Mishra, Shruti Srivastava, KK Jha, RL Khosa. Cassia fistula Linn. (Amulthus)-An Important Medicinal Plant: A Review of Its Traditional Uses, Phytochemistry and Pharmacological Properties. J. Nat. Prod. Plant Resour. 2011; 1(1):101-18. 54. Wang SY, Chen PF, Chang ST. Antifungal activities of essential oils and their constituents from indigenous cinnamon (Cinnamomum osmophloeum) leaves against wood decay fungi. Bio Resour Technol. 2005; 96(7):813-888. 55. Bibekananda Meher, Deepak Kumar Dash, Anupama Roy. A Review On: Phytochemistry, Pharmacology And Traditional Uses Of Tamarindus Indica L. World Journal of Pharmacy And Pharmaceutical Sciences. 2014; 3(10):229-240. 56. Jain Anurekha, Guptha VB. Chemistry and pharmacological profile of guggul-a review. Indian Journal of Traditional Knowledge. 2006; 5(4):478-483. 57. Frances Watkins, Barbara Pendry, Alberto Sanchez-Medina, Olivia Corcoran. Antimicrobial assays of three native British plants used in Anglo-Saxon medicine for wound healing formulations in 10th century England. Journal of Ethnopharmacology. 2012; 144(2): 225–456. 58. Ivanova D, Tasinov O, Vankova D, Kiselova-Kaneva Y. Antioxidative Potential of Agrimonia Eupatoria L. Science & Technologies. 2011; 1(1): 20-24. 59. European Food Safety Authority. Scientific opinion on safety evaluation of ephedra species for use in food: EFSA Panel on food additives and nutrient sources added to food (ANS). EFSA Journal. 2013; 11(11):3467-3479. 60. Sarmad Moin, Sahaya Shibu Babu, Arumugam Mahalakshmipriya. In vitro callus production and antibacterial activity of Barleria lupulina Lindl, AsPac J. Mol. Biol. Biotechnol. 2012; 20(2): 59-64. 61. Papiya Mitra Mazumder et al,. Evaluation of antiarthritic and immunomodulatory activity of Barleria lupulina. Asian Pacific Journal of Tropical Biomedicine. 2012: 1400-1406. 62. Paula do N Batista, Magaly A M de Lyra, Pedro J R Neto, Maria das G F de Medeiros, Rivelilson M de Freitas, Lívio C C Nunes: Systematic Review: Uses, Applications and Therapeutic Trends of Bauhinia forficata Lin. VRI Phytomedicine. 2013; 1(2). 63. K Teja Sri, S Ushasri, M Shalemu Rani, P Yamini Nirmala, P Anjaneyulu. Biophytum sensitivum Dc – An Overview. International Journal of Pharmacological Screening Methods. 2013; 3(2): 2249–7757. 64. Farzana Rashid et al,. Phytochemical analysis and inhibitory activity of Ornamental Plant (Bougainvillea spectabilis). Asian Journal of Plant Science and Research. 2013; 3(2):1-5. 65. H Saikia, A Lama. Effect of Bougainvillea spectabilis Leaves on Serum Lipids in Albino Rats Fed with High Fat Diet. International Journal of Pharmaceutical Sciences and Drug Research. 2011; 3(2):141-145. 66. Manvi, Ganesh Prasad Garg. Evaluation of Pharmacognostical parameters and Hepatoprotective activity in Bryonia alba Linn. Journal of Chemical and Pharmaceutical Research. 2011; 3(6):99-109. 67. Ranjit Singh et al. Screening For Anti-Diabetic Activity of The Ethanolic Extract of Bryonia Alba Roots. IJPBS. 2012; 2(3):210-215. 68. Almeida RN, Filho JMB, Naik SR. Chemistry and pharmacology of an ethanol extract of Bumelia sartorum. J Ethnopharmacol. 1985; 14:173-85. 69. Christopher M Sheahan. PIGEONPEA Cajanus Cajan (L.) Millsp. USDA NRCS Cape May Plant Materials Center, Cape May, NJ, United States Department of Agriculture-National Resource Conservation Service. 70. Manish Gunjan et al. A Review on Some Potential Traditional Phytomedicine with Antidiabetic Properties. International Journal of Phytomedicine. 2011; 3: 448-458. 71. PK Mohanty et al. Preliminary Phytochemical Screening of Cajanus cajan Linn., Research Article. Asian J. Pharm Tech. 2011; 1(2): 49-52. 72. Shanmukha I, Vijay Kumar MI, Ramachandra Setty S. Effect of Tecoma stans Leaves for its Preventive Role on Experimentally Induced Liver Toxicity. International Journal of Pharmtech Research Coden. 2013; 5(3): 915-923. 73. Saraswati A, E Sasikala, A Patra, A Kundu. Betulin- 28 acetate from Capparis sepiaria. Indian Journal of Chemical Society. 1991; 68:633-634. 74. A. Chauhan et al. Plants Having Potential Antidiabetic Activity: A Review. Der Pharmacia Lettre. 2010; 2(3): 369-387. 75. Sofomora LA. Medical Plants and Traditional Medicine in Africa. Spectrum Books Ltd, Ibadan. 1993:55-71. 76. A Elumalai, Nikhitha Mathangi, Adarsh Didala, Raju Kasarla, Yetcharla Venkatesh. A Review on Ceiba pentandra and its medicinal features. Asian J. Pharm. Tech. 2012; 2(3):83-86. 77. Faheem Amir, Koay Yen Chin. The Chemical Constituents and Pharmacology of Centratherum anthelminticum. International Journal of PharmTech Research. 2011; 3(3):1772-1779. 78. MA Shad, H Nawaz, T Rehman, N Ikram. Determination of Some Biochemicals, Phytochemicals and Antioxidant Properties of Different Parts of Cichorium intybus L: A Comparative Study. The Journal of Animal & Plant Sciences. 2013; 23(4):1060-1066. 79. Dr. Sonawane, Suvarna Rambhau, Dr. Deshpande Pradnya Ravindra, Dr. Pande Prasad Prabhakharrao, Dr. Shahane Vijay Chandrakant. Phytochemical & Pharmacological Activity of Agnimantha (Clerodendrum Phlomidis Linn. F). International Journal of Ayurvedic and Herbal Medicine. 2014; 4(5): 1615-1621. 80. Ghani A. Medicinal plants of Bangladesh with chemical constituents and uses. 2nd edn. Asiatic Society of Bangladesh, Dhaka, Ramna. 2003; 1: 184-236. 81. Cravo L, Perineau F, Gaset A, Bessiere JM. Study of the chemical composition of the essential oil, oleoresin and its volatile product obtained from ambrette (Abelmoschus moschtus Morich) seeds. Flavor Fragrance Journal. 1992; 7: 65-67. 82. Zhang J, Sun GB, Lei QF, Li GZ, Wang JC, Si JY. Chemical constituents of lateral roots of Aconitum carmichaelii Debx. Yao Xue Xue Bao. 2014; 49(8): 1150-1154. 83. Guangli Yana, Hui Sunb, Wenjun Sunb, Li Zhaob, Xiangcai Mengb, Xijun Wangb. Rapid and global detection and characterization of aconitum alkaloids in Yin Chen Si Ni Tang, a traditional Chinese medical formula, by ultra performance liquid chromatography–high resolution mass spectrometry and automated data analysis. Journal of Pharmaceutical and Biomedical Analysis. 2010; 53:421–431. 84. Shukla YN, Dubey S, Jain SP, Kumar S. Chemistry, biology and uses of Adansonia digitata – a review. Journal of Medicinal and Aromatic Plant Sciences. 2001; 23:429-434. 85. Sugandha Singh et al. Preliminary Phytochemical Evaluation of In Vivo and In Vitro Plant Parts of Adansonia Digitata L: An Endangered Medicinal Tree. Universal Journal of Pharmacy. 2014; 3(3): 34-40. 86. Young Min Lee et al. Estrogen-like activity of aqueous extract from Agrimonia pilosa Ledeb in MCF-7 cells. BMC Complementary and Alternative Medicine. 2012; 12(260):1472-6882. 87. Xi Liu et al. Glucosidase inhibitory activity and antioxidant activity of flavonoid compound and triterpenoid compound from Agrimonia Pilosa Ledeb. BMC Complementary and Alternative Medicine. 2014; 14:12. 88. KP Sampath Kumar, Debjit Bhowmik, Chiranjib, Biswajit, Pankaj Tiwari. Allium cepa: A traditional medicinal herb and its health benefits. J. Chem. Pharm. Res. 2010; 2(1): 283-291. 89. Suryavanshi VL, Sathe PA, Baing MM, Singh GR, Lakshmi SN. Determination of Rutin in Amaranthus spinosus Linn. Whole Plant Powder by HPTLC. Pharmacognosy Journal. 2007; 2(2): 134-152. 90. Rai Puneet Kumar, Jindal Shammy, Gupta Nitin, Rana Rinu. An Inside Review of Amaranthus Spinosus Linn: A Potential Medicinal Plant of India. IJRPC. 2014; 4(3): 643-653. 91. Available From: Wikipedia, the free encyclopedia. http://en.wikipedia.org/w/index.php?title=Anisodustanguticus&oldid= 606926796. Last reviewed on 14-11-2015. 92. Yogini Jaiswal, Vinayak Naik, Pratima Tatke, Satish Gabhe, Ashok Vaidya. Pharmacognostic and Preliminary Phytochemical Investigations of Anacardium Occidentale (Linn.) Leaves. Int J Pharm Pharm Sci, 2012; 4(3): 625-631. 93. C Eliakim-Ikechukwu, A Obri, O Akpa. Phytochemical and Micronutrient Composition of Anacardium Occidentale Linn (cashew) stem-bark hydroethanolic extract and its effect on the fasting blood glucose levels and body weight of diabetic Wistar rats. The Internet Journal of Nutrition and Wellness. 2010; 10(1): 1-6. 94. Peng W, Liu YJ, Wu N, Sun T, He XY, Gao YX et al. Areca catechu L. (Arecaceae): a review of its traditional uses, botany, phytochemistry, pharmacology and toxicology. J Ethnopharmacol. 2015; 22(164): 340-356. 95. Dar Ahsana, Khatoon, Shagufta. Antidepressant Effects of Ethanol Extract of Areca catechu in Rodents. Phytotherapy Research. 1997; 11(2): 174-176. 96. Mohammed Aziz. Relaxant Effect of Essential Oil of Artemisia herba-alba Asso. on Rodent Jejunum Contractions. Sci Pharm. 2012; 80(2):457-467. 97. Santosh Sharma, Ashwani Kumar. Review Article-Ethno Botany Tribal Uses of Medicinal Plants of Rajashthan: Kachnar. International Journal of Life Science and Pharma Research. 2012; 2(4): 62-68. 98. De Souza P, Gasparotto A, Jr Crestani S. Hypotensive mechanism of the extracts and artemetin isolated from Achillea millefolium L. (Asteraceae) in rats. Phytomedicine. 2011; 18(10):819–825. 99. Li Y, Zhang M, Cong B, Achillinin A. A cytotoxic guaianolide from the flower of yarrow, Achillea millefolium. Bioscience, Biotechnology and Biochemistry. 2011; 75(8):1554–1556. 100. FL Silva, DCH Fischer, JF Tavares, MS Silva, PF De Athayde-Filho, JM Barbosa-Filho. Compilation of secondary metabolites from Bidens pilosa L. Molecules. 2011; 16(2):1070–1102. 101. Arlene P Bartolome, Irene M Villaseñor, Wen-Chin Yang. Bidens pilosa L:(Asteraceae) Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology. Evid Based Complement Alternat Med. 2013; 2013: 1-51. 102. Mohd. Danish et al. Cassia fistula Linn.(Amulthus)-An Important Medicinal Plant: A Review of Its Traditional Uses, Phytochemistry and Pharmacological Properties. J Nat. Prod. Plant Resour. 2011; 1(1): 101-118. 103. Ngueyem TA, Brusotti G, Caccialanza G, Finzi PV. The genus Bridelia: a phytochemical and ethnopharmacological review. J Ethnopharmacol. 2009; 124(3):339-349. 104. Pradeep Singh et al. Traditional uses, phytochemistry and pharmacological properties of Capparis deciduas. Der Pharmacia Lettre. 2011; 3(2): 71-82. 105. Muhammad Zia-Ul-Haq, Sanja Ćavar, Mughal Qayum, Imran Imran, Vincenzo de Feo. Antioxidant and Antidiabetic Activities of Capparis decidua (Forsk.). Edgew, Int. J. Mol.2011; 12(12):8846-8861. 106. Monika Sain, Vandana Sharma. Catharanthus roseus (An anti-cancerous drug yielding plant) - A Review of Potential Therapeutic Properties. Int. J. Pure App. Biosci. 2013; 1(6):139-142. 107. Borhade Pravin, Deshmukh Tushar, Patil Vijay, Khandelwal Kishanchnad. Review On Citrullus Colocynthis. International Journal of Research In Pharmacy And Chemistry. 2013; 3(1):46-53. 108. Pathak Nimish L, Kasture Sanjay B, Bhatt Nayna M, Rathod Jaimik D. Phytopharmacological Properties of Coriander Sativum as a Potential Medicinal Tree: An Overview. Journal of Applied Pharmaceutical Science. 2011; 1(4):25. 109. Surendra, Mukul Bahera, Roop Karki, Chandru Shekar. Preliminary Phytochemical Analysis of Leaf and Bark methanolic extract of Sesbania grandiflora. The Journal of Phytopharmacology (Pharmacognosy and Phytomedicine Research).2012; 1(2):10-20. 110. Alli L.A, Salwau A et al. Antiplasmodial activity aqueous root extract of acacia nilotica. AJBR. 2011; 5:214-219. 111. Mbatchou V.C et al. Antibacterial activities of seed pod extracts of acacia nilotica wild to artemia salina larvae. Journal of Applied Biosciences. 2011; 40:2738- 2745. 112. Li, Rong, Zi-Tao Jiang. Chemical composition of the essential oil of Cuminum cyminum L. from China. Flavour and Fragrance Journal. 2004; 19 (4): 311–313. 113. Thippeswamy N.B, K.Akhilender Naidu. Antioxidant potency of cumin varieties cumin, black cumin and bitter cumin on antioxidant systems. Eur Food Res Technol. 2005;220: 472–476. 114. Shetty R.S, R.S.Singhal, P.R. Kulkarni. Antimicrobial properties of cumin. World Journal of Microbiology & Biotechnology. 1994;10:232–233. 115. Paras Sharma, Gargee Dubey, Sunil Kaushik. Medipoeia Chemical and Medico-biological profile of Cyamopsis tetragonoloba (L) Taub: An overview. Journal of Applied Pharmaceutical Science. 2011; 1(2):32-37. 116. Ganatra et al. Phytochemicals Investigation And TLC Profiling Of Cyamopsis Tetragonoloba L. Seeds (Fabaceae) - Pea Family. International Journal of Pharmaceutical Sciences And Research. 2013; 4(4):1551-1555. 117. Bai B, Li MJ, Wang Y, Liu XH. Studies on chemical constituents of Dioscorea opposite. Zhongguo Zhong Yao Za Zhi.2008; 33(11):1272-1274. 118. Chuan-Sung Chiu et al. Antioxidant and Anti-Inflammatory Properties of Taiwanese Yam (Dioscorea Japonica Thunb. Var. Pseudojaponica (Hayata) Yamam.) And Its Reference Compounds. Food Chemistry.2013; 141(2):1087-1096. 119. Sachin M, Hiradeve, Vinod D, Rangari. Elephantopus scaber Linn.: A review on its ethnomedical, phytochemical and pharmacological profile. Journal of Applied Biomedicine. 2014; 12(2): 49–61. 120. Hardel Danendra Kumar, Sahoo Laxmidhar. A Review on phytochemical and pharmacological of Eucalyptus globules, a multipurpose tree. IJRAP. 2011; 2(5):1527-1530. 121. P.J. Gupta. The efficacy of Euphorbia prostrata in early grades of symptomatic hemorrhoids – a pilot study. European Review for Medical and Pharmacological Sciences. 2011; 15:199-203. 122. Manohar LS, Zabeer A,Shashi B: Phytopharmacological study of Ficus glomerata Review. International Journal of Research in Phytochemistry & Pharmacology. 2013; 3(1):65-69. 123. Mandal SC, Saraswathi B, Kumar CK, Mohana Lakshmi S, Maiti BC. Protective Effect of Leaf Extract of Ficus Hispida Linn, Against Paracetamol-Induced Hepatotoxicity in Rats. Phytother Res. 2000; 14(6): 457-459. 124. Shanmugarajan TS, Devaki T. Hepatic Perturbations Provoked by Azathioprine: A Paradigm to Rationalize the Cytoprotective Potential Of Ficus Hispida Linn. Toxicol Mech Methods. 2009; 19(2): 129-134. 125. Mandal SC, Ashok Kumar CK, Studies On Anti-Diarrhoeal Activity of Ficus Hispida, Leaf Extract In Rats. Fitoterapia. 2002; 73(7): 663-667. 126. Peraza-Sánchez Sr et al. Constituents Of The Leaves And Twigs of Ficus Hispida. Planta Med. 2002; 68(2):186-188. 127. Chetia D, Nath LK, Dutta SK. Pharmacological Properties of a Protease from Ficus Hispiad Linn. Anc Sci Life. 2001; 21(2):99-110. 128. Kostova I. Fraxinus ornus L. Fitoterapia. 2001; 72(5):471-480. 129. Klein-Galczinsky C. Pharmacological and clinical effectiveness of a fixed phytogenic combination trembling poplar (Populus tremula), true goldenrod (Solidago virgaurea) and ash (Fraxinus excelsior) in mild to moderate rheumatic complaints. Wien Med Wochenschr. 1999; 149(8): 248-253. 130. H.O. Lawal, S.O. Etatuvie, A.B. Fawehinmi. Ethnomedicinal and Pharmacological properties of Morinda lucida. Journal of Natural Products. 2012; 5: 93-99. 131. Tao XY et al. Chemical constituents from cell cultures of Morus alba. Zhongguo Zhong Yao Za Zhi. 2012; 37(24): 3738-3742. 132. Muhammad Mohtasheem Ul Hasan et al. Toxicity Assessment Of Mucuna Pruriens Linn, Seeds. International Research Journal Of Pharmacy. 2011; 2 (11): 133-135. 133. Sanjeev Kumar, Chanchal Kumar Mishra, Anil Ahuja, Asha Rani, R.K. Nema. Phytoconstituents and Pharmacological activities of Musaparadisiaca Linn. Asian Journal of Biochemical and Pharmaceutical Research. 2012; 2(4): 199-206. 134. Mohammad Akram Randhawa. Black Seed Nigella Sativa, Deserves More Attention. J Ayub Med Coll Abbottabad. 2008; 20(2): 1-2. 135. N. K. Sharma, D. Ahirwar, D. Jhade, S. Gupta. Medicinal and Phamacological Potential of Nigella sativa, A Review. Ethnobotanical Review. 2009; 13: 946-955. 136. Mabel Parimala, Francis Gricilda Shoba. Phytochemical analysis and in vitro antioxidant activity of hydroalcoholic seed extract of Nymphaea nouchali Burm. F. Asian Pac J Trop Biomed. 2013; 3(11): 887–895. 137. Muhammad Ali Hashmi, Afsar Khan,Muhammad Hanif, Umar Farooq, Shagufta Perveen. Review Article Traditional Uses, Phytochemistry, and Pharmacology of Olea europaea (Olive). Evidence-Based Complementary and Alternative Medicine. 2015; 2015: 1-29. 138. Aslam Khan, Samra Bashir, Saeed R Khan,Anwar H Gilani. Antiurolithic Activity Of Origanum Vulgare is Mediated Through Multiple Pathways. BMC Complementary and Alternative Medicine. 2011; 11(96): 3-16. 139. Lakshmi T, Anitha Roy and Geetha RV. Panax Ginseng A Universal Panacea in the Herbal Medicine With Diverse Pharmacological Spectrum –A Review. Asian Journal of Pharmaceutical and Clinical Research. 2011; 4(1): 14-18. 140. Sook Young Lee, Yong Kyoung Kim, Nam I Park, Chun Sung Kim, Chung Yeol Lee, Sang Un Park. Chemical constituents and biological activities of the berry of Panax ginseng. Journal of Medicinal Plants Research. 2010; 4(5): 349-353. 141. S.R. Arote, P.G. Yeole. Pongamia Pinnata L: A Comprehensive Review. International Journal of Pharmtech Research Coden.2010; 2(4): 2283-2290. 142. Rakesh Raturi, S.C. Sati, Harpreet Singh, M. D. Sati, P. Bahuguna, P. P. Badoni. Chemical Examination and Anti Inflammatory Activity Of Prunus Persica Steam Bark. Int J Pharm Pharm Sci. 2011; 3(5): 315-317. 143. Sumaira Aziz, Habib-ur-Rahman. Biological activities of Prunus persica L. batch. Journal of Medicinal Plants Research. 2013; 7(15):947-951. 144. Wei Han et al. Prokinetic Activity of Prunus persica (L.) Batch Flowers Extract and Its Possible Mechanism of Action in Rats. BioMed Research International. 2015; 2015:1-10. 145. Jing Liu et al. Comparison of the Immunoregulatory Function of Different Constituents in Radix Astragali and Radix Hedysari. Journal of Biomedicine and Biotechnology. 2009; 2010 (2010):1-12. 146. Wang YS. Pharmacology and application of Chinese material medico. Beijing: People’s Health Publisher. 1983;775-778. 147. Wu BJ. Pharmacology and application of Chinese material medico. Beijing: People’s Health Publisher. 1983; 41-43. 148. Ying Chen et al. Antioxidant Activities of Saponins Extracted From Radix Trichosanthis: An In Vivo And In Vitro Evaluation. BMC Complementary and Alternative Medicine. 2014; 14(86):1-8. 149. Ping He, Li Shuai, Su-Juan Wang, Yong-Chun Yang, Jian-Gong Shi. Study on chemical constituents in rhizome of Pinellia ternata . China Journal Of Chinese Materia Medica 2005; 30(9): 671-674. 150. Xiao Ji, Baokang Huang, Guowei Wang, Chunyan Zhang: The ethnobotanical, phytochemical and pharmacological profile of the genus Pinellia. Fitoterapia. 2014; 93: 1–17. 151. Jie-Wen Guo, Jian-Mei Chen, Li-Jing Lin,Feng Xu: Five chemical constituents of the ethyl acetate fraction from ethanol extract of semen litchi. Journal of Medicinal Plants Research. 2012; 6(1):168-170. 152. Samia Rashid, Qaiser Iftikhar, Mohammad Arshad, Javed Iabal. Chemical composition and antibacterial activity of Suaeda Fruticosa Forsk. Pakistan Journal of Biological Sciences. 2000; 3(2): 348-349. 153. Ekta Singh, Sheel Sharma, Ashutosh Pareek, Jaya Dwivedi, Sachdev Yadav, Swapnil Sharma. Phytochemistry, traditional uses and cancer chemopreventive activity of Amla (Phyllanthus emblica): The Sustainer. Journal of Applied Pharmaceutical Science. 2011;2(1): 176-183. 154. Klinger Antonio da Franca Rodrigueset al. Eugenia uniflora L. Essential Oil as a Potential Anti-Leishmania Agent: Effects on Leishmania amazonensis and Possible Mechanisms of Action. Evid Based Complement Alternat Med. 2013; 2013:1-10. 155. Consolini AE, Baldini OA, Amat AG. Pharmacological basis for the empirical use of Eugenia uniflora L. (Myrtaceae) as antihypertensive. J Ethnopharmacol. 1999; 66 (1): 33–39. 156. Matsumura et al. A-glucosidase Inhibitors From Paraguayan Natural Medicine, Nangapiry, the Leaves of Eugenia uniflora. Pharm Biol. 2000; 38(4): 302–307. 157. Ogunwande IA, Olawore NO, Ekundayo O, Walker TM, Schmidt JM, Setzer WN. Studies on the essential oils composition, antibacterial and cytotoxicity of Eugenia uniflora L. International Journal of Aromatherapy. 2005; 15(3): 147–152. 158. Amorim ACL, Lima CKF, Hovell AMC, Miranda ALP, Rezende CM. Antinociceptive and hypothermic evaluation of the leaf essential oil and isolated terpenoids from Eugenia uniflora L. (Brazilian Pitanga). Phytomedicine. 2009; 16(10): 923–928. 159. Costa DP, et al. Influence of fruit biotypes on the chemical composition and antifungal activity of the essential oils of Eugenia uniflora leaves. Journal of the Brazilian Chemical Society. 2010; 21(5): 851–858. 160. Schapoval EE, Silveira SM, Miranda ML, Alice CB, Henriques AT. Evaluation of some pharmacological activities of Eugenia uniflora L. J Ethnopharmacol. 1994;44(3):137–42. 161. Manjeshwar Shrinath Baliga, Harshith P. Bhat, Bantwal Raghavendra Vittaldas Baliga, Rajesh Wilson, Princy Louis Palatty. Phytochemistry, traditional uses and pharmacology of Eugenia Jambolana Lam (black plum): A review. Food Research International. 2011; 44(7):1-14. 162. He Lan et al. Study on the chemical constituents of Euonymus alatus (Thunb.) Sleb. Journal of Zhejiang University Science. 2000;1(2):188-189. 163. Kim CH et al. Euonymus alatus (Thunb.) Sieb induces apoptosis via mitochondrial pathway as pro-oxidant in human uterine leiomyomal smooth muscle cells. Int J Gynecol Cancer. 2006; 16(2):843-848. 164. Mitra Heydari Nasrabadi, Helia Aboutalebi, Maryam Naseri. Effect of Fumaria parviflora alcoholic extract on male rat’s reproductive system. Journal of Medicinal Plants Research. 2012; 6(10):2004-2010. 165. Luka CD, Omoniwa BP. Effect Of Some Phytochemicals Extracted From Goat's Rue (Galega Officinalis) On Some Biochemical Parameters In Normal And Alloxan-Induced Diabetic Rats. Journal of Natural Product & Plant Resources. 2012; 2(5): 628. 166. H Rasekh, I Hoseinzadeh, P Nazari, M Kamalinejad. Acute toxicity of galega officinalis alcoholic extract in Wistar rats. Iranian Journal of Pharmaceutical Research. 2004; 3(2): 45-45. 167. Gabriel. F Ibikunle, Emmanuel O. Ogbadoyi. Pharmacological Evaluation Of Garcinia kola Nuts For Anti-Trichomonal Activity. International Journal Of Pharma and Bio Sciences. 2011; 2(2):264-269. 168. Ogunmoyole T, Olalekan OO, Fatai O, Makun JO, KadeI .J. Antioxidant and phytochemical profile of aqueous and ethanolic extract of Garcinia kola. Journal of Pharmacognosy and Phytotherapy. 2012; 4(5): 66-74. 169. Ajay K. Dixit, JIX Antony, Navin K Sharma, Rakesh K Tiwari. Soybean constituents and their functional benefits. Opportunity, Challenge and Scope of Natural Products in Medicinal Chemistry. 2011;367-383. 170. EEJ Iweala, FO Uhegbu, OA Adesanoye. Biochemical effects of leaf extracts of Gongronema latifolium and selenium supplementation in alloxan induced diabetic rats. Journal of Pharmacognosy and Phytotherapy. 2013; 5(5):91-97. 171. PA Akah, SU Uzodinma, CE Okolo. Antidiabetic activity of aqueous and methanol extract and fractions of Gongronema latifolium (Asclepidaceae) leaves in Alloxan Diabetic Rats. Journal of Applied Pharmaceutical Science. 2011;1(9):99-102. 172. Christian E Odo, Osmund C Enechi, , Uzoma Eleke,. Anti-diarrhoeal potential of the ethanol extract of Gongronema latifolium leaves in rats. African Journal of Biotechnology. 2013; 12(27): 4399-4407. 173. Pornanong Aramwit, Suntchai Wirotsaengthong. Overview of commonly used Chinese herbs. Journal of Medicinal Plants Research. 2012; 6(29): 4505-4521. 174. Anil Kumar et al. Review on Hibiscus rosa sinensis. International Journal of Research in Pharmaceutical and Biomedical Sciences. 2012; 3(2): 534-538. 175. Sanjana Tharaka et al. Humulus lupulus in Management of Orodental Pathogens –An Update. J. Pharm. Sci. & Res. 2013; 5(9):187-189. 176. Drewes SE, Hall AJ, Learmonth RA, Upfold UJ: Isolation of hypoxoside from Hypoxis rooperi and synthesis of (E)-1,5- bis (3’,4’-dimethoxyphenyl) pent-4-en-1-yne. Phytochemistry. 1984; 23(6): 1313-1316. 177. Van Staden J. Constituents of Hypoxis rooperi, a valuable medicinal plant in South Africa. Deutsche Apotheke Zeitung. 1981; 33: 460-464. 178. Drewes SE, Elliot E, Khan E, Dhlamini JTB, Gcumisa MSS: Hypoxis hemerocallidea–not merely a cure for benign prostate hyperplasia. J. Ethnopharmacol. 2008; 119(3):593-598. 179. Sharma Ashwini Kumar. Medicinal value of Inula Racemosa hook. F (pushkarmoola). Unique Journal of Ayurvedic and Herbal Medicine. 2014; 2(2): 11-13. 180. Gautam P Vadnere, Ram S Gaud, Abhay Kumar Singhai, RS Somani: Effect of Inula racemosa root extract on various aspects of asthma. Pharmacology online. 2009; 2: 84-94. 181. Ijaola TO et al. Antidiabetic Effect of Ipomoea batatas in Normal and Alloxan-Induced Diabetic Rats. IOSR Journal of Applied Chemistry. 2014; 7( 5):16-25. 182. N M Reddy: Lantana Camara Linn. Chemical Constituents and Medicinal Properties: A Review. Scholars Academic Journal of Pharmacy. 2013; 2(6): 445-448. 183. Gagandeep Chaudhary, Sandeep Goyal, Priyanka Poonia, Lawsonia inermis Linnaeus: A Phytopharmacological Review. International Journal of Pharmaceutical Sciences and Drug Research. 2010; 2(2): 91-98. 184. Divanji Manohar, GLViswanatha, S Nagesh, Vishal Jain, HN Shivaprasad. Ethnopharmacology of Lepidium Sativum Linn (Brassicaceae): A Review.International Journal of Phytothearpy Research. 2012; 2(1).1-7. 185. Meena Devi VN, Ariharan VN, Nagendra Prasad P. Nutritive Value and Potential Uses of Leucaena Leucocephala as Biofuel–A Mini Review. Research Journal of Pharmaceutical, Biological and Chemical Sciences. 2013; 4(1): 515-521. 186. Liu W, Wang ZL, Liang HQ. Studies on the chemical constituents of liriope spicata var proliferaytma. Yaoxue Xuebao. 1989; 24(10): 749-754. 187. M. Upendra Rao, M Sreenivasulu, B Chengaiah, K Jaganmohan Reddy, C Madhusudhana Chetty. Herbal Medicines for Diabetes Mellitus: A Review. International Journal of PharmTech Research. 2010; 2(3):1883-1892. 188. Papageorgiou VP, Assimopoulou AN, Couladouros EA, David Hepworth, Nicolaou KC Angew. The chemistry and biology of alkannin, shikonin and related naphthazarin natural products. Chem. Int. Ed. Engl. 1999; 38:270– 300. 189. Fatima A. Mohammad. Some biochemical effects of Lupinus albus L. seed oil on normal and alloxan induced diabetic mice. Tikrit Journal of Pure Science. 2010; 15(1): 1-5 190. Suhad S Humadi, Viorica Istudor: Lythrum Salicaria (Purple Loosestrife) Medicinal Use, Extraction and Identification of its Total Phenolic Compounds. FARMACIA. 2009; 57(2): 192-200. 191. Rajnish Gupta, RS Gupta: Antidiabetic Efficacy Of Mangifera Indica Seed Kernels in Rats: A Comparative Study With Glibenclamide. Diabetologia Croatica. 2011; 40(4): 107-112. 192. P Kemasari, S Sangeetha, P Venkatalakshmi. Antihyperglycemic activity of Mangifera indica Linn. in alloxan induced diabetic rats. Journal of Chemical and Pharmaceutical Research. 2011; 3(5): 653-659. 193. D Sai Koteswar Sarma, A Venkata Suresh Babu, K Rama Krishna, PP Nagoor Basha. Phytochemical studies and biological activities on fruits of Momordica Cochinchinensis. J.Chem.Pharm.Res. 2011;3(4): 875-881. 194. Vandana Jain, Munira Momin, Kirti Laddha. Murraya Koenigii, An Updated Review. International Journal of Ayurvedic And Herbal Medicine. 2012; 2(4): 607:627. 195. Nishkruti R Mehta, Ekta P Patel Pragnesh V Patani, Biren Shah. Nelumbo Nucifera (Lotus): A Review on Ethanobotany, Phytochemistry and Pharmacology. Indian J.Pharm.Biol.Res. 2013;1(4):152-167. 196. Subzar Ahmad Sheikh. Ethno-medicinal uses and pharmacological activities of lotus (Nelumbo nucifera). Journal of Medicinal Plants Studies. 2014; 2(6): 42-46. 197. MK Mohan Maruga Raja, Neeraj Kumar Sethiya, SH Mishra. A comprehensive review on Nymphaea stellata, A traditionally used bitter. J Adv Pharm Technol Res. 2010; 1(3): 311–319. 198. Danmalam UH, Idoko VE, Yaro AH, Magaji MG, Agunu A, Abdurahman EM. Phytochemical and Anticonvulsant Screening of the Aqueous Ethanol Extract of Combretum Micranthum G. don. Root. Nigerian Journal of Pharmaceutical Sciences. 2011; 10(1): 32-38. 199. Udoh IP, Nworu CS, Eleazar CI, Onyemelukwe FN, Esimone CO. Antibacterial profile of Extract of Combretum micranthum G. don against resistant and sensitive nosocomial isolates. Journal of Applied Pharmaceutical Sciences. 2012; 2(4): 142-146. 200. Rachel Nimenibo–Uadia. Control of hyperlipidaemia, hypercholesterolaemia and hyperketonaemia by aqueous extract of Dioscorea dumetorum tuber. Tropical Journal of Pharmaceutical Research. 2003; 2(1): 183-189. 201. SV Bakiyalakshmi, Dr. M Boominathan. In-Vitro Pharmacological Activity Of Flavonoid Isolated From Njavara (Oryza Sativa). BmrPhytomedicine. 2014; 1(1): 1-10. 202. Barbara Kołodziej, Radosław Kowalski, Elżbieta Hołderna-Kędzia. Chemical composition and chosen bioactive properties of Panax quinquefolius extracts. chemija. 2013; 24(2):151–159. 203. Dong-Yi He, Sheng-Ming Dai: Anti-Inflammatory And Immunomodulatory Effects Of Paeonia Lactiflora Pall, A Traditional Chinese Herbal Medicine. Front Pharmacol. 2011; 2(10): 1-5. 204. Bernard Matur, Matthew Malau, Ifeanyi Titus, Casmir IC Analysis of the phytochemical and invivo antimalaria properties of Phyllanthus fraternus webster extract. New York Science Journal. 2009; 2(5): 12-19. 205. Jit Narayan Sah, Vinay Kumar Varshney. Chemical Constituents Of Picrorhiza Genus: A Review. American Journal of Essential Oils and Natural Products. 2013; 1(2): 22-37. 206. Zaichangyang, Runzi Du, Aoshuang Chang, Jian Zhang and Qiang Li. The In Vitro Anti-Biofilm Activity of the Etoac Extract Of Poria Cocos Against Escherichia Coli. Asian Journal Of Pharmaceutical Research and Development. 2013; 1(4): 152-156. 207. Jin Woo Jeong et al. Ethanol Extract of Poria Cocos reduces the production of inflammatory mediators by suppressing the NF-KappaB Signalling Pathway in Lipopolysaccharide stimulated RAW 264.7 Macrophages. BMC Complimentary and Alternative Medicine. 2014; 14(101): 1-8. 208. Baby Joseph, Mini Priya R. Review On Nutritional, Medicinal And Pharmacological Properties Of Guava (Psidium Guajava Linn). International Journal Of Pharma And Bio Sciences .2011; 2(1): 53-69. 209. Julie Jurenka Mt. Therapeutic Applications of Pomegranate (Punica Granatum L.): A Review. Alternative Medicine Review. 2008; 13(2): 128-144. 210. Yi-Chian Wu and Ching-Liang Hsieh. Pharmacological Effects of Radix Angelica Sinensis (Danggui) On Cerebral Infarction. Chin Med. 2011; 6(32): 1-5. 211. Dr. Bhawana Mittal, Dr. Meenakshi, Dr. Anita Sharma, Dr. Vinod Kumar Gothecha.Phytochemical & Pharmacological Activity Of Rauwolfia Serpentina– A Review. International Journal of Ayurvedic and Herbal Medicine. 2012; 2(3): 427-434. 212. Reeta Kumaria, Brijesh Rathib, Anita Ranic, Sonal Bhatnagar. Rauvolfia Serpentina L. Benth. Ex Kurz.: Phytochemical, Pharmacological and Therapeutic Aspects. Int. J. Pharm. Sci. Rev. Res. 2013; 23(2): 348-355. 213. NE Hamdani, R Fdil. Evaluation of Fatty Acids Profile and Mineral Content of Retama Monosperma (L.) Boiss. of Morocco. J. Mater. Environ. Sci. 2015; 6(2): 538-545. 214. Olorunfemi A Eseyin, Munavvar A Sattar and Hassaan A Rathore. A Review of The Pharmacological and Biological Activities of the Aerial Parts Of Telfairia Occidentalis Hook. F. Tropical Journal of Pharmaceutical Research. 2014; 13(10): 1761-1769. 215. Prakash Chandra Gupta. Biological and Pharmacological Properties of Terminalia Chebula Retz. (Haritaki)-An Overview. International Journal of Pharmacy and Pharmaceutical Sciences. 2012;4(3): 62-68. 216. Eric Wei Chiang Chan, Lea Ngar Tan, SiuKuin Wong. Phytochemistry and Pharmacology of Lagerstroemia Speciosa: A Natural Remedy For Diabetes. International Journal of Herbal Medicine. 2014; 2(2): 100-105. 217. Rajamani Saranya, Thirunavukkarasu Thirumalai, Munisami Hemalatha, Ranganathan Balaji, Ernest David. Pharmacognosy of Enicostemma littorale: A Review. Asian Pac J Trop Biomed. 2013; 3(1): 79–84. 218. Love S Chokotia, Pranav Vashistha, Rajkumar Sironiya, Harsha Matoli. Pharmacological Activities of Eclipta Alba (L.). International Journal of Research and Development in Pharmacy And Life Sciences. 2013; 2(4): 499-502. 219. Vinod M Thakare, Rajesh Y Chaudhari, Vijay R Patil. Potential Medicinal Plant Cynodon dactylon (L.) Pers. Asian Journal of Pharmaceutical Sciences and Research. 2011; 1(6): 3477-3483. 220. Ethan B Russo. Phytochemical and Genetic Analyses of Ancient Cannabis from Central Asia. Journal of Experimental Botany. 2008; 59(5): 4171-4182. 221. Rudolf Brenneisen. Chemistry and Analysis of Phytocannabinoids and Other Cannabis Constituents. Forensic Science And Medicine. 2007: 17-49. 222. Anu Walia, Rajat Malan, Satish Saini, Vipin Saini and Sumeet Gupta. Hepatoprotective Effects from the Leaf Extracts of Brassica Juncea in Ccl 4 Induced Rat Model. Der Pharmacia Sinica. 2011; 2(4): 274-285. 223. B Radhika, Nasreen Begum, K Sreesailam, VM Reddy. Diuretic Activity Of Bixa Orellanalinn. Leaf Extract. Indian Journal of Natural Products and Resources. 2010; 1(3): 353-355. 224. K Ashok Kumar, SK. Gousia, Anupama MJ Naveena Lavanya Latha. A Review On Phytochemical Constituents and Biological Assays of Averrhoa Bilimbi. International Journal of Pharmacy and Pharmaceutical Science Research. 2013; 3(4): 136-139. 225. Saurabh Srivastav, Pradeep Singh, Garima Mishra, KK Jha, RL Khosa. Achyranthes aspera-An important medicinal plant: A review. J. Nat. Prod. Plant Resour. 2011; 1(1):1-14. 226. Atul Kumar Gangwar, Ashoke K Ghosh. Medicinal uses and Pharmacological activity of Adhatoda vasica. International Journal of Herbal Medicine. 2014; 2(1): 88-91. 227. Martha Thomson, Zainab M Al-Amin, Khaled K Al-Qattan, Lemia H Shaban, Muslim Ali. Anti-diabetic and hypolipidaemic properties of garlic (Allium sativum) in streptozotocin-induced diabetic rats. Int J Diabetes & Metabolism. 2007; 15:108-115. 228. Londhe VP, Gavasane AT, Nipate SS, Bandawane DD, Chaudhari PD. Role of Garlic (Allium Sativum) in Various Diseases, An Overview. Journal of Pharmaceutical Research and Opinion. 2011; 1(4): 129-134. 229. Ali Esmail Al-Snafi. The Pharmaceutical Importance of Althaea officinalis and Althaea rosea, A Review. International Journal of PharmTech Research. 2013; 5(3): 1378-1385. 230. Anil Kumar, Jyotsna Dora, Anup Singh and Rishikant Tripathi. A Review On King Of Bitter (Kalmegh). International Journal Of Research In Pharmacy And Chemistry.2012; 2(1); 116-124. 231. Zhishu Tang et al., Anemarrhena asphodeloides Non-Steroidal Saponin Components Alter the Pharmacokinetic Profile of Its Steroidal Saponins in Rat. Molecules.2015; 20: 11777-11792. 232. Gajalakshmi S, Vijayalakshmi S, Devi Rajeswari V. Phytochemical and Pharmacological Properties Of Annona Muricata, A Review. International Journal of Pharmacy and Pharmaceutical Sciences. 2012; 4(2): 3-6. 233. Neha Pandey, Dushyant Barve. Phytochemical and Pharmacological Review on Annonas quamosa Linn. International Journal of Research in Pharmaceutical and Biomedical Sciences. 2011; 2(4): 1404-1412. 234. Suresh J, Vasavi Reddy A, Dhanya Rajan, Ihsanullah M, Mohd. Nayeemmullah Khan. Antimicrobial Activity of Artemisia abrotanum and Artemisia pallens. International Journal of Pharmacognosy and Phytochemical Research. 2010; 3(2): 18-21.