Antimicrobial Activities of the Ethanol Extracts of Mirabilis jalapa L. and Euphorbia dendroide.

Authors

  • Muhammad Ikram Department of Botany, Hazara University, Mansehra,Pakistan.
  • Gul Jan Department of Botany, Hazara University, Mansehra,Pakistan.
  • Saim Dad Department of Botany, Hazara University, Mansehra,Pakistan.
  • Nasrullah Department of Plant Sciences, Quaid-I-Azam University, Islamabad, Pakistan.
  • Suliman Department of Botany, Hazara University, Mansehra,Pakistan.
  • Hina Fazl Pakistan Council of Scientific and Industrial Research (PCSIR), Peshawar, Pakistan.

Keywords:

Antimicrobial, Antibacterial, Disc diffusion method

Abstract

Antimicrobial activity was examined from two selected plants: Mirabilis jalap L. (stem, leaves and seeds) and Euphorbia dendroide (stem, leaves and root) different parts were screened against seven bacterial strains; three Gram positive (Staphlyococus aureus, Bacillus subtilis and Bacillus atropoeusand), four Gram negative (Escherichia coli, Pseudomonas aeruginosa, Salmonila typhi and Kleibsiella pneumonia) and one fungal strain Candida albican. Antibacterial activity was determined by the disc diffusion method; crude extracts were obtained by using ethanol as the extraction solvent. Two concentrations (6 mg/ml and 12 mg/ml) were used to check the antimicrobial activity of plant extracts. The result showed that Euphorbia dendroide different parts extracts were more active against gram negative bacteria and fungal strain then Mirabilis jalap L. while both plants showed good activity against gram positive bacteria. Azithromycin, Ciprofloxacin and Clotrimezole (50 µg/ml) were used as a standard drugs

References

. Weisser R, Asscher AW, Winpenny J

(1966). Invitro reversal of antibiotic

resistance by DTA. Nature, 219: 1365-

. Akinpelu D.A. andOnakoya T.M.(2006)

Antimicrobial activities of medicinal

plants used in folklore remedies in

south-western. African Journal of

Biotechnology Vol. 5 (11), pp. 1078-

,

. Alagesaboopathi C.(2011). Antimicrobial

screening of selected medicinal plants in

Tamilnadu, India. African Journal of

Microbiology Research Vol. 5(6) pp.

-621

. Abramowics M (1990). The choice of

antimicrobial drugs. Medical letter on

Drugs and Therapeutics, 32: 41-

. Sridhar TM, Josthna P and Naidu CV

(2011). In VitroAntibacterial Activity and

Phytochemical Analysis of

Solanumnigrum(Linn.) - An Important

Antiulcer Medicinal Plant. Journal of

Experimental Sciences , 2(8): 24-29

. Encarnación DR, Virgen M, Ochoa N

(1998). Antimicrobial activity of

medicinal plants from Baja California Sur

(Mexico). Pharm. Biol., 36: 33-43

. Marquez B, Neuville L, Moreau NJ,

Genet JP, Santos AF, Andrade MCC,

Sant Ana AEG (1999). Multidrug

resistance reversal agent from

Jatrophaelliptica. Phytochemistry, 66:

-1811.

. Holdsworth D (1992. Medicinal Plants of

the East and West Sepik Provinces,

Papua New Guinea. Int. J.

Pharmacogn., 30(3): 218-222

. Comerford SC (1996). Medicinal plants

of two Mayan healers from San Andrés,

Petén, Guatemala. Econom. Bot., 50(3):

-336.

. Moreira MD (1996). Compounds from

Mirabilis jalapa: Isolation, structural

elucidation and insecticidal activity. Pest.

Manage. Sci., 63: 615ă621.

. De Bolle MF, Osborn RW, Goderis IJ,

Noe L, Acland D, Hart CA, Torrekens S,

Van Leuven F, Broekaert WF (1996).

Antimicrobial peptides from Mirabilis

jalapaand Amarantuscaudatus:

Expression, processing, localization and

biological activity in transgenic tobacco.

Plant Mol. Biol., 31(5): 993ă1008

. Vivanco JM, Querci M, Salazar LF

(1999). Antiviral and antiviroid activity of

MAP-containing extracts from Mirabilis

jalaparoots. Plant Dis., 83: 1116-1121

. Oska M, Sari D (2007). Antimicrobial

screening of some Turkish medicinal

plants. Pharm. Biol., 45: 176-181.

. Siddiqui S, Siddqui BS, Adil Q, Begum S

(1990). Constituents of Mirabilis jalapa.

Fitoterapia, 61: 471.

. Somavilla N, Canto-Dorrow TS (1996).

Levantamento das

plantasmedicinaisutilizadasembairros de

Santa Maria-RS. Ciênciae. Natura, 18:

-148.

. Lai XZ, Yang YB, Shan XL (2004). The

Investigation of Euphorbiaceous

Medicinal Plants in Southern China.

Econ. Bot., 58: S307-S320.

. Nasir E, Ali SI (1971-95). Flora of

Pakistan. Nos. 1-190. Department of

Botany, Karachi University, Karachi.

Pak. Agric. Res. Council Islamabad,

Pakistan.

. Ali SI &Qaiser M (1995-2004). Flora of

Pakistan, Department of Botany,

University of Karachi, Pakistan.

. Stewart RR (1967). Checklist of plants

Swat state, Northwest Pakistan. Pak. J.

For. , 4(2): 457 528.

. Stewart RR (1982). History and

exploration of plants in Pakistan and

adjoining areas, National Herbarium,

NARC, Islamabad.

. Tona, L., K.Kambu,N. Nigimbi, K.

Cimanga and A.J.Vlietinck (1998).

Antiamoebic and phytochemical

screening of some Congolese medicinal

plants.J.of Ethnopharmacology.57-65.

. Mahesh B, and Satish S (2008).

Antimicrobial activity of some important

medicinal plant against plan and

humenpathogen.world journal of

agricultural science 4(S): 839-843.

Downloads

Published

31-12-2013

How to Cite

1.
Muhammad Ikram, Gul Jan, Saim Dad, Nasrullah, Suliman, Hina Fazl. Antimicrobial Activities of the Ethanol Extracts of Mirabilis jalapa L. and Euphorbia dendroide. ijp [Internet]. 2013 Dec. 31 [cited 2024 Dec. 6];5(4):475-8. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/287

Issue

Section

Original Research Articles