Analysis of Radiotherapy and chemotherapy induced toxicity on rodents (Swiss albino) and pharmacological importance of Pistia stratiotes
Keywords:
Radiotherapy, chemotherapy, Pistia stratiotes, Herbal medicine, Phytochemical screeningAbstract
Herbal medicines has been reported to play an important role i n the discovery of new drugs for t he treatment of human diseases, including cancer [1]. Many herbal remedies have shown to play anticancer role through multiple mechanisms. Our present work i s an at t em pt t o screen s om e essential components from the water weed Pistia stratiotes and to study its potentiality against the side effects induced by radiotherapy and chemotherapy
References
. Evans HJ. Molecular
mechanism in theinductio n
of chromosome aberrations
Holand Biomedical P ress.
; 57-74.
. Ganesh C Jagetia et al.
Radioprotectivepotential o f
plants an d h erbs against
the effect of ionising
radiation. Journal of clinical
biochemistry, Nutrition.
;40:74-81.
. Schuchter L M et al. The
current status o f W R 2721
(Amifostine : a
chemotherapy and
radiotherapy prot ect or” .
Biologic Therapy Cancer
updates. 1993 3; 1-10,.
. Jagitia G C et al. Radiation
modifyingeffect of Ocimum
santum on mousesurvival.
Annual of National
academy of sciences.
(India), 1986.
. Goel H. C et al.
Radioprotection b y herbal
preparation o f Hippobhae
rhamnoides, RH -3againt
whole body lethal
irradiation in mice.
Phytomedicine. 2002 9;15-
. Salin C A et al. Protection
of mousejeujenum against
the lethal irradiation by
Podophyllum h exandrum .
Phytomedicine. 2001;8:
-422,.
. Mittal A et al. I nfluence of
Podophyllum h exandrum
on endogenous anti -
oxidant defence system i n
mice : Possible role in radio
protection. Journal of
ethnopharmacol.
;76:253-262.
. Goel H. C et al.
Radioprotective potentialof
herbal extract of Tinospor a
cordefolia. Journal of
Radiation Research.
;45:61-68.
. Dische S et al. A radomized
multicentertrail o f CHART
vs conventional
radiotherapy in h ead and
neck cancer” . Radiotherapy
Oncology. 1979;44:123-136,
.NHGRI Chromosome
Abnormalities, 2006. Gupta,
SS. Prospects and
Prespective of natural
plants products in
medicine, Indian Journal o f
Pharmacology :26:1-12,
.Farns Worth NR. Medicinal
plants in therapy Bulletin of
the World Health
Organization 1985 63
no.6:965-981.
.Andrew Vickers, Catherine
Zollman and Roberta L ee,
Herbal medicine. BMJ 1999
:1050-1053.
.Arora R et al.
Radioprotection b y plant
products: Present status
and future prospects.
Phytotherapy research.
;19:1-22.
.Borris RP. Natural
products research
prespectives from a m ajor
pharmaceutical company, J
Ethanopharmacol.
Moreman D.E, “ An analysis
of food plants drug plants
of native north America” , J.
Ethanopharmacol, 1996;52.
.Thomas M Zennie and
Jerry W.McClure,
Pietro Monaco and
Lucio Previtera, 1991
.Anamika Tewari et al.,
“ A melioration o fmu ncipal
sludge by Pistia stratiotes
L:Role of antioxidant
enzymes indetoxification of
metals.” 2008.
.M D Mukhtar et al. 2004.
.Ling Y et al. 1999.Medicinal
plants of east and
southeastAsia. By L.M
Perry. MIT
Press,Cambridge`. Hand
book of E ner gyCrops. By
J.Duke, 1980.
.Tropical feeds. Feed
informationsummaries and
nutritive value. By B.Gohl.
FAO Animal Production
andHealth Series 12. F AO,
Rome. Handbook of Energy
Crops. By J.Duke, 1981.
.Making aquatic weeds
useful. NationalAcademy of
Sciences (or
N.A.S.),Washingto n, DC.
.Amirhosein Ahemed et al.,
“ Prev ent i v eeffects of
hesperidin as a
flavanoid,against
genotoxicity induced
bycyclophosphamide. 2008.
.Yogeshwari Shukla and
MadhulikaSingh, “ Canc er
preventive property
ofginger : A bri ef r ev i ew ” .
Food andchemical
Toxicology. 2007 ;45; 683-
.Deendayal Patel et al ., “
Epigenin andcancer
chemoprevention :
Progress,potential and
prom i se” .
InternationalJournal of
Oncology. 2006 ;30:233 -
,.
.Niture et al., “
Chemopreventive
strategies, targeting the
MGMT repairprotein :
Augmented expression
inhuman lymphocytes and
tumor cells byethanolic and
acqueous extracts
ofseveral indian medicinal
pl ant s.” International
Journal of Onology.
;1269-1278, 2006.
.A A Izzo et al ., “ Eat i ng
garlic andonion : A matter
of Li fe or deat h” . British
Journal of Cancer. 2004;91;
,.
.Gauri Sh ankar S A, T ani
Das, “ Anticancereffects o f
Curcumin : Cycle of lifean d
death.” Bi om ed. (Cel l
Division). 2008 3-14.
.Annelyse Duvoix et al.,
“ Chemopreventive and
therapeutic effectsof
Curcumin” . Cancer Letters.
-3; 181-190, 2004.
.Gajulla D. et al ., “
Determination of
totalPhenolics, Flavanoids
and Antioxidant
andchemopreventive
potential of
Basi l”.International Journal
of Cancer Research.
;5(4):130-143,.
.Shilpa S and Ganesh N et
al ., “ Tumorinhibition and
cytotoxicity assay
byaqueous extract of onion
and garlic : Invitro
anal y si s” . International
Journal ofPhytomedicine.
;2; 80-84.
.Chi Chen et al ., “ Di et ary
chemopreventivecompound
s and ARE / EpRE
si gnal l i ng” .Free radical
Biology and Medicine.
;1505-1516, 2004.
.Imad Shureiqr et al ., “
Chemoprevention :A
general prespective” .
OncologyHematology.
;33:157-167,.