Analysis of Radiotherapy and chemotherapy induced toxicity on rodents (Swiss albino) and pharmacological importance of Pistia stratiotes

Authors

  • S. Patil Department of Research, Jawaharlal Nehru Cancer Hospital & Research Center, Idgah Hills, Bhopal, India.
  • N. Dhele Department of Research, Jawaharlal Nehru Cancer Hospital & Research Center, Idgah Hills, Bhopal, India.
  • S. Pawar Dr. D. Y. Patil Biotechnology & Bioinformatics Institute, Thatawade, Pune.
  • N. Ganesh Department of Research, Jawaharlal Nehru Cancer Hospital & Research Center, Idgah Hills, Bhopal, India.

Keywords:

Radiotherapy, chemotherapy, Pistia stratiotes, Herbal medicine, Phytochemical screening

Abstract

Herbal medicines has been reported to play an important role i n the discovery of new drugs for t he treatment of human diseases, including cancer [1]. Many herbal remedies have shown to play anticancer role through multiple mechanisms. Our present work i s an at t em pt t o screen s om e essential components from the water weed Pistia stratiotes and to study its potentiality against the side effects induced by radiotherapy and chemotherapy

References

. Evans HJ. Molecular

mechanism in theinductio n

of chromosome aberrations

Holand Biomedical P ress.

; 57-74.

. Ganesh C Jagetia et al.

Radioprotectivepotential o f

plants an d h erbs against

the effect of ionising

radiation. Journal of clinical

biochemistry, Nutrition.

;40:74-81.

. Schuchter L M et al. The

current status o f W R 2721

(Amifostine : a

chemotherapy and

radiotherapy prot ect or” .

Biologic Therapy Cancer

updates. 1993 3; 1-10,.

. Jagitia G C et al. Radiation

modifyingeffect of Ocimum

santum on mousesurvival.

Annual of National

academy of sciences.

(India), 1986.

. Goel H. C et al.

Radioprotection b y herbal

preparation o f Hippobhae

rhamnoides, RH -3againt

whole body lethal

irradiation in mice.

Phytomedicine. 2002 9;15-

. Salin C A et al. Protection

of mousejeujenum against

the lethal irradiation by

Podophyllum h exandrum .

Phytomedicine. 2001;8:

-422,.

. Mittal A et al. I nfluence of

Podophyllum h exandrum

on endogenous anti -

oxidant defence system i n

mice : Possible role in radio

protection. Journal of

ethnopharmacol.

;76:253-262.

. Goel H. C et al.

Radioprotective potentialof

herbal extract of Tinospor a

cordefolia. Journal of

Radiation Research.

;45:61-68.

. Dische S et al. A radomized

multicentertrail o f CHART

vs conventional

radiotherapy in h ead and

neck cancer” . Radiotherapy

Oncology. 1979;44:123-136,

.NHGRI Chromosome

Abnormalities, 2006. Gupta,

SS. Prospects and

Prespective of natural

plants products in

medicine, Indian Journal o f

Pharmacology :26:1-12,

.Farns Worth NR. Medicinal

plants in therapy Bulletin of

the World Health

Organization 1985 63

no.6:965-981.

.Andrew Vickers, Catherine

Zollman and Roberta L ee,

Herbal medicine. BMJ 1999

:1050-1053.

.Arora R et al.

Radioprotection b y plant

products: Present status

and future prospects.

Phytotherapy research.

;19:1-22.

.Borris RP. Natural

products research

prespectives from a m ajor

pharmaceutical company, J

Ethanopharmacol.

Moreman D.E, “ An analysis

of food plants drug plants

of native north America” , J.

Ethanopharmacol, 1996;52.

.Thomas M Zennie and

Jerry W.McClure,

Pietro Monaco and

Lucio Previtera, 1991

.Anamika Tewari et al.,

“ A melioration o fmu ncipal

sludge by Pistia stratiotes

L:Role of antioxidant

enzymes indetoxification of

metals.” 2008.

.M D Mukhtar et al. 2004.

.Ling Y et al. 1999.Medicinal

plants of east and

southeastAsia. By L.M

Perry. MIT

Press,Cambridge`. Hand

book of E ner gyCrops. By

J.Duke, 1980.

.Tropical feeds. Feed

informationsummaries and

nutritive value. By B.Gohl.

FAO Animal Production

andHealth Series 12. F AO,

Rome. Handbook of Energy

Crops. By J.Duke, 1981.

.Making aquatic weeds

useful. NationalAcademy of

Sciences (or

N.A.S.),Washingto n, DC.

.Amirhosein Ahemed et al.,

“ Prev ent i v eeffects of

hesperidin as a

flavanoid,against

genotoxicity induced

bycyclophosphamide. 2008.

.Yogeshwari Shukla and

MadhulikaSingh, “ Canc er

preventive property

ofginger : A bri ef r ev i ew ” .

Food andchemical

Toxicology. 2007 ;45; 683-

.Deendayal Patel et al ., “

Epigenin andcancer

chemoprevention :

Progress,potential and

prom i se” .

InternationalJournal of

Oncology. 2006 ;30:233 -

,.

.Niture et al., “

Chemopreventive

strategies, targeting the

MGMT repairprotein :

Augmented expression

inhuman lymphocytes and

tumor cells byethanolic and

acqueous extracts

ofseveral indian medicinal

pl ant s.” International

Journal of Onology.

;1269-1278, 2006.

.A A Izzo et al ., “ Eat i ng

garlic andonion : A matter

of Li fe or deat h” . British

Journal of Cancer. 2004;91;

,.

.Gauri Sh ankar S A, T ani

Das, “ Anticancereffects o f

Curcumin : Cycle of lifean d

death.” Bi om ed. (Cel l

Division). 2008 3-14.

.Annelyse Duvoix et al.,

“ Chemopreventive and

therapeutic effectsof

Curcumin” . Cancer Letters.

-3; 181-190, 2004.

.Gajulla D. et al ., “

Determination of

totalPhenolics, Flavanoids

and Antioxidant

andchemopreventive

potential of

Basi l”.International Journal

of Cancer Research.

;5(4):130-143,.

.Shilpa S and Ganesh N et

al ., “ Tumorinhibition and

cytotoxicity assay

byaqueous extract of onion

and garlic : Invitro

anal y si s” . International

Journal ofPhytomedicine.

;2; 80-84.

.Chi Chen et al ., “ Di et ary

chemopreventivecompound

s and ARE / EpRE

si gnal l i ng” .Free radical

Biology and Medicine.

;1505-1516, 2004.

.Imad Shureiqr et al ., “

Chemoprevention :A

general prespective” .

OncologyHematology.

;33:157-167,.

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Published

30-09-2012

How to Cite

1.
S. Patil, N. Dhele, S. Pawar, N. Ganesh. Analysis of Radiotherapy and chemotherapy induced toxicity on rodents (Swiss albino) and pharmacological importance of Pistia stratiotes. ijp [Internet]. 2012 Sep. 30 [cited 2024 Nov. 23];4(3):355-61. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/186

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Original Research Articles