Antioxidant, haemolytic activities and GC-MS profiling of Carissa carandas roots.

Authors

  • Farah Aslam Department of Chemistry, Government College University Faisalabad-38400, Pakistan
  • Nasir Rasool Department of Chemistry, Government College University Faisalabad-38400, Pakistan
  • Muhammad Riaz Department of Chemistry, Government College University Faisalabad-38400, Pakistan
  • Muhammad Zubair Department of Chemistry, Government College University Faisalabad-38400, Pakistan
  • Komal Rizwan Department of Chemistry, Government College University Faisalabad-38400, Pakistan
  • Mazhar Abbas Department of Chemistry and Biochemistry, University of Agriculture, Faisalabad- 8040, Pakistan
  • Tanveer Hussain Bukhari Department of Chemistry, Government College University Faisalabad-38400, Pakistan
  • Iftikhar Hussain Bukhari Department of Chemistry, Government College University Faisalabad-38400, Pakistan

Keywords:

Antioxidants, corn oil, Carissa carandas, roots, lipids

Abstract

The antioxidant potential of the plant Carissa carandas roots extracted with different polarity based solvents was assessed. The antioxidant activity was evaluated by the measurement of total phenolic contents (TPC), total flavonoid contents (TFC), reducing power, DPPH radical scavenging, IC50 and antioxidant activity in linoleic acid system. The plant material contained the TPC (1.79-4.35 GAE mg/g of dry extract), TFC (1.91-3.76 CE mg/g of dry extract), DPPH radical scavenging activity, IC50 (12.53-84.82 %) and % inhibition of peroxidation in linoleic acid (41.0-89.21 %) system respectively. Furthermore the antioxidant effectiveness of extracts was assessed using corn oil (CO) as the oxidation substrate. The oxidative alterations were evaluated by the measurement of conjugated diene (CD), conjugated triene (CT), panisidine, free fatty acid (FFA) and peroxide values (PV). The cytotoxicity of the plant extracts were assessed against human red blood cells (RBCs) and the % lysis was found to be in the range of 1.01-6.10 %. The GC-MS analysis of n-hexane extract was also profiled. It was concluded that extracts of plant roots may be used as potential source of antioxidant agents in food industries.

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Published

31-12-2011

How to Cite

1.
Farah Aslam, Nasir Rasool, Muhammad Riaz, Muhammad Zubair, Komal Rizwan, Mazhar Abbas, Tanveer Hussain Bukhari, Iftikhar Hussain Bukhari. Antioxidant, haemolytic activities and GC-MS profiling of Carissa carandas roots. ijp [Internet]. 2011 Dec. 31 [cited 2024 Dec. 7];3(4):567-78. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/138

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