Phytochemical and Pharmacological potential of Flemingia Roxb. ex W.T.Aiton (Fabaceae)
Keywords:
Flemingia strobilifera, F. macrophylla, F.chappar, Fabaceae, FlavonoidsAbstract
The Flemingia genus is an important source of medicinal natural products, particularly Flavonoids and steroids. The collected information is an attempt to cover the more recent developments in the ethnobotany, pharmacology and phytochemistry of this genus. The review includes 39 references on the genus Flemingia, and comprises ethnopharmacology, morphology, phytoconstituents, pharmacological reports, clinical study and adverse effects of the prominent species of Flemingia. A few species of this genus have medicinal value, among these, F.strobilifera ,F.macrophylla, F.chappar (Fabaceae) have been traditionally used in the treatment of epilepsy, insomnia, ulcer, pain ,swelling. Despite a long tradition of use of some species, the genus has not been explored properly. In the concluding part, the future scope of Flemingia species has been emphasized with a view to establish their multifarious biological activities and mode of action. The information summarized here is intended to serve as a reference tool to practitioners in the fields of ethnopharmacology and natural products chemistry.
References
. Badwaik H, Singh MK, Thakur D, Kumar
T Giri, Tripathi DK.The Botany
,Chemistry,Pharmacological and
Therapeutic application of Oxalis
corniculata Linn. International Journal of
Phytomedicine.2011, (3) 1-8.
. Anonymous, The Wealth of India, Raw
Materials, Publication and Information
Directorate, CSSIR, New Delhi, 1993,
vol.4th pp.45-48.
. http://en.wikipedia.org/wiki/Flemingia.
. Wei Yuetsung. The classification and
distribution of the genus flemingia roxb.ex
ait.in china.Guihaia. 1991, 03.
. Sa Ren, Michael G. Gilbert. . FLEMINGIA
Roxburgh ex W. T. Aiton, Hort. Kew., ed.
, 4: 349. 1812, nom. cons., not Roxburgh
ex Rottler. Flora of China .2010, 10, 232–
. Oudhia, P. Medicinal herbs of chhattisgarh,
India having legumes Traditional uses,
VIII.Manjholi Galfulli (Flemingia
chappar). Botanical.com. 2003.
. http://www.science20.com/humboldt_fell
ow_and_science/blogspot."Plants used in
folk medicine in India believed to have
medicinal potential by users of folk
medicine in India".
. http://uvp.blogspot.com/2006.05/flemingia.
html UBINVOLUNTEERS.
. Kirtikar, K.R. and Basu, B.D., Indian
Medicinal Plants, 1993, Vol.1, pp.814-815.
. http://www.stuartxchange.org/panapanarah
an/payang-payang.html.
. http://toptropicals.com/cgibin/garden_catalog/cat.cgi.
. http://www.flowersofindia.in/catalog/slides
/Wild%20Hops.html.
. Adityachaudhary N, Ghosh D,
ChoudharyA, Kirtaniya CL.
flemichapparin-A a new chromenochalcone
isolated from Flemingia chappar. Journal of
the Indian chemical society.1973; 59
(5):363-4.
. Adityachaudhary N, Gupta PK. New
pterocarpan and coumestan in the roots of
Flemingia chappar.
Phytochemistry.1973;12 (2):425-8.
. Dhar DN, Singh RK, Munjal RC. Chemical
examination of Flemingia chappar. Root
constituents.
Monatsh.Chem.1971;102(6):1777-81.
. Rao CP, Vemuri VSS, Rao KVJ. Chemical
examinations of roots of Flemingia stricta
Roxb. (Leguminosae). Indian journal of
chemistry.1982; 21B (2): 167-9.
. Sivarambabu S, Rao JM, Rao KVJ.New
flavanones from the roots of Flemingia
stricta roxb. Indian journal of chemistry.
;17B(1): 85-7
. Rastogi PR, Mehrotra BM. compendium of
Indian medicinal plants vol. 2 CDRI ,
Lucknow,1991; P323.
. Subramanyam K, Rao JM, Vemuri VSS,
Babu SS, Roy CP, Rao KVJ, Merlini L.
New chalcones from the leaves of
flemingia stricta Roxb.,
(Leguminosae)Indian journal of Chemistry.
;21B (9) :895-7.
. Rao JM, Subrahmanyam K, Jagannadha
KV, Ramaih TS. New chalcones from the
leaves of Flemingia stricta
Roxb.(Leguminosae) . Indian journal of
chemistry. 1976;14B (5): 339-42.
. Nageshwara K, Srimannarayana G.
Fleminone a flavanone from the stems of
Flemingia macrophylla, Journal of
Phytochemistry. 1983; 22(10) : 2287-2290.
. Nageshwara K, Srimannarayana G.
Flemiphyllin an isoflavone from stems of
Flemingia macrophylla, Journal of
Phytochemistry 1984; 23(4): 927-929.
. Saxena VK, Nigam SS, Singh RB.
Glycosidic principles from the leaves of
Flemingia strobilifera. Planta Medica.
; 29(91):94-7.
. Bhatt S. Chalcones and some other
constituents of Flemingia strobilifera
Indian journal of Chemistry.
;13(100):1105-08.
. Madan S, Singh GN, Kumar Y. A New
Flavanone from Flemingia strobilifera
(Linn) R.Br. and its Antimicrobial Activity.
Trop J Pharm Res. 2008 Mar; 7 (1): 921-
. Madan S, Singh GN, Kanchan K.
Isoflavonoids from Flemingia Strobilifera
(L) R.Br. roots. Acta Poloniae
Pharmaceutica-Drug research. 2009 66(3):
-303.
. Supplements of Indian herbs vol.1.
. Rao HSP, Reddy KS. Isoflavones from
Flemingia vestita Fitoterapia. 1991;62(5)
:458.
. Compendium of Indian medicinal plants,
and phytochemistry. 1973.
. M Chen, S Q Luo, J H Chen. Studies on the
chemical constituents of Flemingia
philippinensisby Acta pharmaceutica Sinica
.1991; 26( 1): 42-48
. Glossary of Indian Medicinal plants with
active principles part -1(A-K).1965-1981.
. Madan S, Singh GN, Kumar Y, Kanchan
K. Phytochemical analysis and free-radical
scavenging activity of Flemingia
strobilifera (Linn) R. Br. Research Journal
of Pharmaceutical,Biological and Chemical
Sciences.2010;1 (4): 183.
. Anil Kumar KV, Babul D, Rama T.
Evaluation of anti-ulcerogenic properties
from the root of Flemingia strobilifera.
Journal of Basic and Clinical Pharmacy
.2011;002 (001).
. Hui-Ya Ho, Jin-Bin Wu , Wen-Chuan Lin.
Flemingia macrophylla Extract
Ameliorates Experimental Osteoporosis in
Ovariectomized Rats Evidence-based
Complementary and Alternative Medicine.
; 7(4).
. Hsieh PC, Ho YL, Huang GJ, Huang MH,
Chiang YC, Huang SS, Hou WC, Chang
YS. Hepatoprotective effect of the aqueous
extract of Flemingia macrophylla on
carbon tetrachloride-induced acute
hepatotoxicity in rats through anti-oxidative
activities. Am J Chin Med, 2011;
(2):349-65.
. Shiao YJ.,Wang CN, Wang WY,Lin YZ.,
Neuroprotective flavonoids from
F.macrophylla. J. Of Planta Medica.2006;
(9): 835-840.
. Das B, Tandon V, Saha N. Anthelmintic
efficacy of Flemingia vestita (Fabaceae):
alterations in glucose metabolism of the
cestode, Raillietina echinobothrida.
Parasitology International .2004; 53(4):
-350.
. Tandon V, Das B, Saha N. Anthelmintic
efficacy of Flemingia vestita (Fabaceae):
Effect of genistein on glycogen metabolism
in the cestode, Raillietina echinobothrida.
Parasitol Int. 2003 Jun; 52(2):179-83
. Kar PK, Tandon V, Saha N. Anthelmintic
efficacy of Flemingia vestita: genisteininduced effect on the activity of nitric oxide
synthase and nitric oxide in the trematode
parasite, Fasciolopsis buski. Parasitol Int.
Sep; 51(3):249-57.
