Phyto-pharmacology of Momordica dioica Roxb. ex. Willd: A Review
Keywords:
Momordica dioica, Cucurbitaceae, phytochemical constituents, Parora, pharmacological actions, kakoraAbstract
Momordica dioica Roxb. ex. Willd (Cucurbitaceae ) is commonly known as a biiter gourd. It is traditionally used as astringent, febrifuge, antiseptic, anthelmintic, spermicidal. Also Used in bleeding piles, urinary infection and as a sedative. Studies indicate that it possesses antioxidant, hepatoprotective, antibacterial, anti-inflammatory, anti-lipid peroxidative, hypoglycemic and analgesic properties. This review aims to highlight the ethnobotany, pharmacognostic and pharmacological uses of Momordica dioica
References
Duthie JF .Flora of the upper Gangatic plans.
Botanical survey of India.Calcutta, 1965,
:89-91.
Khare CP. Encyclopedia of Indian Medicinal
Plants .Springer. New York, 2004:104.
Kirtikar KR, Basu BD. Indian Medicinal
Plants. International Book Distributors,
Dehradun, 1999,2:1129-1135.
Nadkarni KM. Medicinal plants of India.
Reprint publication Dehradon. India. 2004:
-237.
Oommachan M. The flora of Bhopal .J.K.
Jain brothers, Bhopal. India, 1977 .180-181.
Chopra RN, Nayar SL, Chopra ZC. Glossary
of Medicinal Plants of India. Publication
Council of Scientific of industrial Research
New Delhi. 1956:169.
Ram D, Kalloo G, Banerjee MK. Popularizing
kakrol and kartoli: the indigenous
nutritious vegetables. Indian Horticulture.
, 6:9-11.
Rashid MM. Bangladeshi shabjee.1st ed.
Bangla academy .Dhaka, Bangladesh, 1976,
Singh AK. Cytogenetics and evaluation in the
cucurbitaceous In ; Bats ,DM ,Robinson RW
and Jaffy , C (eds ) .Biology and utilization of
cucurbitaceae .Comstock Publishing
Associates ,Cornell Univ. Press ,Ithaca , New
York and London. 1990: 10-28.
Kirtikar KR, Basu BD. Indian Medicinal
Plants. Lalit Mohan Basu, Allahabad, India.
, 2:11-2.
Sharma GK. Medical ethnobotany in the
Shivalik Range of the Himalayas. Journal of
the Tennessee Academy of Science.
,7:12-16.
Nadkarni KM. In Indian materia medica,
Populer prakashan. Bombay, 1976: 807.
Satyavati GV, Gupta AK ,Tandon N. In
Medicinal plants of India, vol.2, ICMR, New
Delhi, 1987 :287.
Satyavati GV, Raina MK, Sharma M .In
Medicinal plants of India, vol. 1, ICMR New
Delhi, 1987:327.
Anjaria J, Parabia M, Bhatt G, Khamar R.
Natural heals: A glossary of selected
indigenous medicinal plants of India .Sristi
innovations 2nd edition .Ahamedabad, 2002:
PLANTS Database, database (version 4.0.4)
(1996). National Plant Data Center, NRCS,
USDA. Baton Rouge, LA 70874-4490 USA.
Misra P, Pal NL, Guru PY, Katiyar J, Tandon
JS. Antimalarial Activity of Traditional Plants
against Erythrocytic Stages of Plasmodium
berghei. Pharmaceutical Biology. 1991, 29:
- 23.
Gupta PP, Simal RC, Tandon JS. Antiallergic
activity of some traditional Indian medicinal
plants. International Journal of
pharmacognosy. 1993, 31(1) :15-18.
Shreedhar CS, Pai KSR, Vaidya VP
.Postcoital antifertility activity of the root of
Momordica dioica Roxb .Indian J
Pharmaceuticals Sciences . 2001,6: 528-531.
Ilango K, Maharajan G, Narasimhan, S.
Analgesic and Anti-inflammatory Activities
of Momordica dioica Fruit Pulp. Natural
product sciences. 2003, 9(4):210-212.
Narsimhan S, Kannan S, Maharajan G.
Antifectent activity of Momordica dioica
fruit pulp extract on Spodoptera Litura.
Fitoterapia . 2005, 76(7-8):715-717.
Kushwaha SK, Jain A, Jain A, Gupta VB,
Patel JR. Hepatoprotective activity of the
fruits of Momordica dioica. Nigerian Journal
of Natural Products and Medicine, 2005, 9:
-31.
Thirupathi Reddy G, Ravikumar B, Krishna
mohan G, Ramesh M. Antihyperglycemic
activity of Momordica dioica Roxb. ex.wild
fruits in alloxan –induced diabetic rats . Asian
J Pharmacodynamics and Pharmacokinetics.
,6:327-329
Mishra D, Shukla AK, Dubey AK, Dixit
AK, Singh K. Insecticidal activity of
vegetable oils against Mustard aphid
,Lipaphis erysimi Kalt. under field condition
.Journal of Oleo Science ,2006, 55 :227-231.
Mishra D, Shukla AK, Tripathi KK, Singh
A, Dixit AK, Singh K. Efficacy of
application of vegetable seed oils as grain
protectant against infestation by
Callosobruchus chinensis and its effect on
milling fractions and apparent degree of
dehusking of legume-pulses. J Oleo Sci.
, 56:1-7.
Thirupathi K, Satesh KS, Govardhan P,
Ravikumar B, Rams Krishna D, Krishna
mohan G . Protective effect of Momordica
dioica against hepatic damage caused by
carbon tetrachloride in rats .Acta
Pharmceutics Sciencia . 2006, 48:213-222.
Jain A, Soni M, Deb L. Antioxident and
hepatoprotective activity of ethanolic and
aqueous extracts of Momordica dioica Roxb.
Leaves. Journal of Ethnopharmacology, 2008,
: 115-118
Luo L, Li Z. Two new triterpenes of urosolic
acids from Momordica dioica. Acta
.Bot.Yunn, 1997, 19:316-320.
Sadyojatha AM, VaidyaVP. Chemical
constituents of rhizome of Momordica dioica
Roxb.International seminar on recent treands
in pharmaceutical sciences. Ootacamund.
, 46:18-20.
Gosh PN, Dasgupta BB, Sircar PK.
Purification of lectin from a tropical plant
Momordica dioica Roxb. ex.Wild . Indian
Journal of Experimental Biology. 1981,
:253-225.
Ali M, Srivastava V. Characterization of
phytoconstituents of Momordica dioica.
Indian J Pharma. Sci, 1998, 60: 287-289.
Jian CC, Ming HC, Rui LN, Geoffrey A,
Cordell SX. Cucurbitacins and cucurbitane
glycosides: structures and biological
activities. Nat. Prod. Rep., 2005, 22:386–
Sadyojatha AM, Vaidya VP. Chemical
constituents of the roots of Momordica dioica
Roxb . Indian drugs, 1996, 39: 473-475.
Luo L, Li Z, Zhang Y, Huang R. Triterpenes
and steroidal compounds from Momordica
dioica.Yao-Xue-Xue-Bao, 1998, 33: 839-42.
Sinha S , Debnath B, Guha A, Sinha RK.
Sex Linked Polypeptides in Dioecious
Momordica dioica. Cytologia. 2001,66:55-58.
Joshi SR, Vasantha K, Robb JS. An unusual
anti –H lectin inhibited by milk from
individuals with the Bombay phenotype
Immunohematology, Journal of Blood group
serology and Education, 2005, 21:1-4.
Tirmizi SA, Hamid M, Watto S, Mazhar M,
Wattoo FH, Menon AN, Iqbal J. Analytical
investigation of Chromium and Zinc in
Sweet, sour and bitter testing fruits vegetables
and medicinal plants .Quim. Nova.
,30:1573-1577.
Ali A, Deokule SS. Studies on nutritional
values of some wild edible plants from Iran
and India .Pakistan Journal of Nutrient. 2008,
: 26-31.
Nabi SA, Rasid MM, Al-Amin M, Rasul
MG. Organogenesis in Teasle gourd
(Momordica dioica Roxb.). Plant Tissue Cult.
, 12: 173-180.
Deokar PL , Panchabhai DM, Tagade UG.
Tissue culture studies in spine gourd
(Momordica dioica Roxb.).Annals of plant
physiology, 2003, 17(1): 64-69.
Thiruvengadam M, Rekha KT, Yang CH.
Somatic Embryogenesis and Plant
Regeneration from Petiole-Derived Callus of
Spine Gourd (Momordica dioica Roxb. ex
Willd). Functional Plant Science and
Biotechnology Global Science Books. 2007:
-206.
Yasuhiro C, Yukio O, Hiroshi O, Shikanori
M. Induction of Octoploids in Kakrol
(Momordica dioica Roxb.). Science bulletin
of the Faculty of Agriculture, Kyushu
University. 2006, 61: 055-061.
Mohammad GR, Mohammad AKM,
Yasuhiro C, Yukio O, Hiroshi O. Application
of Plant Growth Regulators on the
Parthenocarpic Fruit Development in Teasle
Gourd (Kakrol, Momordica dioica Roxb.). J.
Fac. Agr., 2008, 53:39–42.