A Study on FTIR, Antimicrobial, Antioxidant and Hypogycaemic Effect of Diospyros Kaki and Citrullus colocynthis

Authors

  • Hemadri Reddy Salla Biology section, Department of Applied Science, Higher College of Technology, Al Khuwair, Po box: 74, postal code: 117, Muscat, Sultanate of Oman.
  • Marwah Rashid Humood Al Jahwari Biology section, Department of Applied Science, Higher College of Technology, Al Khuwair, Po box: 74, postal code: 117, Muscat, Sultanate of Oman
  • Zeinab Mohammed Rashid Al Tobi Biology section, Department of Applied Science, Higher College of Technology, Al Khuwair, Po box: 74, postal code: 117, Muscat, Sultanate of Oman

Keywords:

FT IR, Antioxidant, Hypoglycaemic, C. colocynthis and D. kaki

Abstract

Phytochemical, FTIR screening, Hypoglycemic study, antibacterial, antifungal and antioxidant activity of Citrullus colocynthis and D. kaki fruit were studied. The interest of this study is to evaluate traditional herbal usage to treat many diseases around the sultanate of Oman locally. The functional groups that they contain are (O-H) Phenol, (C-H) Alkyl, (N-H) Amine and (C=C) Alkenyl groups corresponds to their biological phytoconstituents responsible for the medicinal properties. The antibacterial and antifungal activities revealed that all parts of tested samples shown good antimicrobial properties. While leaf of C. colocynthis methanolic extract showed highest zone of inhibition (24.33 mm³) against penicillium. Antioxidant assays were evaluated through DPPH (1, 1- diphenyl-2-picryllhydrazyi) and H2O2 (Hydrogen peroxide scavenging capacity) methods. Peel of D. kaki extract showed higher antioxidant activities than other parts. Antioxidant property of these fruit is due to the presence of significant amount of tannins, phenolic acids and flavonoids on them. A slight change in body weight was observed in all mice compared to the control. All extracts except leaf of C. colocynthis show significant reduction in blood glucose level even more than the positive control which treated with metformin drug. From our investigation of screening different parts of two plants, the results obtained confirm the therapeutic value of both plants used in traditional medicine.

References

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Sobia K, A JM, Rehmatullah AMS, Hina Q, Iram G, Pervaiz B, et al. Assessments of Phytochemicals and Hypoglycemic Activity of Leaves of Carica papaya in Diabetic

Mice. International Journal of Pharmaceutica Science and

Research. 2016;7(9):3658–3665.

Dallak M, Bin-Jaliah I; 2010.

Al-Ghaithi F, El-Ridi MR, Adeghate E, Amiri MH. Biochemical effects of Citrullus colocynthis in normal and

diabetic rats. Molecular and Cellular Biochemistry.

;261(1):143–149. Available from: https://dx.doi.org/

1023/b:mcbi.0000028749.63101.cc.

Butt MS, Sultan MT, Aziz M, Naz A, Ahmed W, Kumar N, et al. Persimmon (Diospyros kaki) fruit: hidden phytochemicals and health claims. EXCLI Journal.

;14:542–561.

Huseini HF, Darvishzadeh F, Heshmat R, Jafariazar Z,

Raza M, Larijani B. The clinical investigation ofcitrullus

colocynthis(L.) schrad fruit in treatment of Type II diabetic

patients: a randomized, double blind, placebo-controlled

clinical trial. Phytotherapy Research. 2009;23(8):1186–

Available from: https://dx.doi.org/10.1002/ptr.2754.

Wani BA, Ramamoorthy D, Ganai BA. Preliminary Phytochemical Screening and Evaluation of Analgesic Activity

of Methanolic Extract of Roots of GentianakurrooRoyle

in Experimental Animal Models. International Journal

of Pharmacy and Pharmaceutical Sciences. 2011;3:975–

Pharmacopoeia E. General Organization for Governmental

Printing Office. Cairo. 1984;.

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Published

30-06-2019

How to Cite

1.
Hemadri Reddy Salla, Marwah Rashid Humood Al Jahwari, Zeinab Mohammed Rashid Al Tobi. A Study on FTIR, Antimicrobial, Antioxidant and Hypogycaemic Effect of Diospyros Kaki and Citrullus colocynthis . ijp [Internet]. 2019 Jun. 30 [cited 2024 Oct. 15];11(2):23-31. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/618

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Original Research Articles