Diabetes mellitus treatment using herbal drugs


  • Sonia Verma Delhi Pharmaceutical Science and Research University Pushp Vihar, Sector-3 MB Road, New Delhi-110017
  • Madhu Gupta Delhi Pharmaceutical Science and Research University Pushp Vihar, Sector-3 MB Road, New Delhi-110017
  • Harvinder Popli Delhi Pharmaceutical Science and Research University Pushp Vihar, Sector-3 MB Road, New Delhi-110017
  • Geeta Aggarwal Delhi Pharmaceutical Science and Research University Pushp Vihar, Sector-3 MB Road, New Delhi-110017


Diabetes mellitus, Herbal drugs, extract, traditional medicine, polyherbal


Diabetes mellitus is becoming a common metabolic disorder which has serious threat to public health in the world. There are chemicals and biochemical agent that helps in controlling diabetes but there is no permanent remedy available which helps to get recovered completely from this disorder. By conducting large number of research work, numerous traditional medicines have been found for diabetes. Substances and extracts isolated from different natural resources especially plants have always been a rich arsenal for controlling and treating diabetes problem and complication arising due to it. So this review helps the reader to understand the importance of various types of herbal and polyherbal formulations present traditionally which can be used to treat diabetes mellitus.


Kumar A, Goel MK. Jain RB, Khanna P, Chaudhary V. India towards diabetes control: Key issues. Australasian Medical Journal.2013;(6):524–531.

Rahimi M. A Review: Anti Diabetic medicinal plants used for diabetes mellitus. Bulletin of environmental, pharmacology and life. Sciences.2015;(4):163–180.

Rao MU. Sreenivasulu M, Chengaiah B, Reddy KJ, Chetty CM. Herbal Medicines for Diabetes Mellitus. A Review International Journal of PharmTech Research. 2010;(2):1883– 1892.

Bordoloi R, Dutta KN. A Review on Herbs Used in the Treatment of Diabetes mellitus.Journal of Pharmaceutical,Chemical and Biological. Sciences.2014;(2):86–92.

Wannes WA, Marzouk B. Research progress of Tunisian medicinal plants used for acute diabetes. Journal of Acute Disease.2016;5(5):357–363.

Edition; Edition; http://www.vision2020uk.org.uk/idf- diabetes-atlas-7thedition.

Available from: http://www.arogyaworld.org/wp- content/uploads/2010/10/arogyaworldINDIAdiabetes factsheets CGI2013 web.

Ozkum D. Akı O, Toklu HZ. Herbal medicine use among diabetes mellitus patients in Northern Cyprus. Journal of Medicinal Plants Research.2013;(7):1652–1664.

Narayan DS, Patra VJ, Dinda SC. Diabetes and indian traditional medicines an overview.International. Journal of Pharmacy and Pharmaceutical Sciences.2012;(4).

Recent TP. Trends in Therapeutic Approaches for Diabetes Management: A Comprehensive Update. Journal of Dia- betes Research.2015:11.

Kumari MS. Lakshmi KN, Prasanna TVVNL, Swapna K, Jyothi AS, Prasanth T. Natural herbs vs allopathic drugs: to treat diabetes. Indo american journal of pharmaceutical sciences.2016;(3):415–422.

Tabatabaeimalazy O. larijani B, Abdollahi M. Targeting metabolic disorders by natural products. Journal of dia- betes & metabolic disorder.2015:14–57.

Reddy VS. Sahay RK, Bhadada SK, Agrawal JK, Agrawal NK. Newer Oral Antidiabetic Agents.JournalIndian. Academy of Clinical Medicine.2000;1(3);.

Prabhakar PK, Doble M. Mechanism of action of natural products used in the treatment of diabetes mellitus. Chin J integr med.2011;(17).

Kumar K, Fateh V, Verma B, Pandey S. Some herbal drugs used for treatment of diabetes : review article.International. vol. 2014.

Galor SW. Benzie IF. Herbal medicine : an introduction to its history, usage, regulation, current trends and;. Research needs.2011.

Gupta R. Bajpai KG, Johri S, Saxena M. An overview of indian novel traditional medicinal plants with antidiabetic potentials.Complementary and Alternative. Medicines.2008;(5):1–17.

Malvi R, Jain S, Khatri S, Patel A, Mishra S. A Review on Antidiabetic Medicinal Plants and Marketed Herbal Formulations. International Journal of Pharmaceutical & Biological Archives.2011;(2):1344–1355.

Gebreyohannes G, Gebreyohannes M. Medicinal values of garlic: A review.International. Journal of Medicine and Medical Sciences.2013;(5):401–408.

Lakshmi MS. Rani KSS, Reddy UKT. A review on diabetes mellitus and the herbal plants used for its treatment. Asian. journal of pharmaceutical and clinical research.2012;(5):15–21.

Mishra R, Shuaib M, Shravan M, S P. A review on herbal antidiabetic drugs. Journal of Applied Pharmaceutical Science.2011;1(6):235–237.

Arumugam G, Manjula P, Paari N. A review: Antidiabetic medicinal plants used for diabetes mellitus. Journal of acute diseases. 2013.

Giovannini P, Jayne MR, Howes E, E S. Medicinal plants used in the traditional management of diabetes and its sequelae in Central America: a review.Journal of. Ethnopharmacology.2016;(2).

Dwivedi CP, Daspaul S. Antidiabetic herbal drugs and polyherbal formulation used for diabetes: A review. The journal of phytopharmacology.2013;(2):44–51.

Khan Y. Aziz I, Bihari B, Kumar H, Roy M, Verma VK. A Review- Phytomedicines Used in Treatment of Diabetes. Asian Journal of Pharmaceutical research.2014:4–3.

Kumar D, Trivedi N. Dixit RK. Herbal medicines used in the traditional Indian medicinal system as a therapeutic treatment option for diabetes management: A review. World Journal of Pharmacy and Pharmaceutical Sci- ences.2015;4(4).

Ozougwu JC. Anti-diabetic effects of Allium cepa (onions) aqueous extracts on alloxan-induced diabetic Rattus novergicus. Journal of Medicinal Plants Research.2011;(5):1134–1139.

Nugroho AE, Andrie M, Warditiani NK, Siswanto E, Pra- mono S, Lukitaningsih E. Antidiabetic and antihiperlipidemic effect of Andrographis paniculata (Burm. f.) Nees and andrographolide in high-fructose-fat-fed rats. Indian journal of pharmacology.2012;44(3):377–381.

Khan BA, Abraham A, Leelamma S. Hypoglycemic action of Murraya koeingii (curry leaf) and Brassica juncea (mustard): mechanism of action. Indian Journal of Biochemistry and Biophysics.1995;(32):106–108.

Abesundara KJ, Matsui T M, K. Alpha-glucosidase inhibitory activity of some Sri Lanka plant extracts one of which Cassia auriculata exerts a strong antihyperglycemic effect in rats comparable to the therapeutic drug acarbose. Journal of Agricultural and Food Chemistry.2004;(52):2541–2545.

Platel K, Srinivasan K. Plant foods in the management of diabetes mellitus: vegetables as potential hypoglycemic agents. Die. 1997;41–68.

Aggarwal N, Shishu. A Review of Recent Investigations on Medicinal Herbs Possessing Antidiabetic Properties. Nu- tritional disorders and therapy.

Ravi K, Ramachandran B, Subramanian S. Protective effect of Eugenia jambolana seed kernel on tissue antioxidants in streptozotocin-induced diabetic rats. Biological and Pharmaceutical Bulletin;2004:27–1212.

Ghosh R, Sharachandra KH, Rita S. Hypoglycemic activ- ity of Ficus hispida (bark) in normal and diabetic albino rats. Indian Journal of Pharmacology. 2004;36(4):222– 225.

JL S, JT A, LA L, V V. Null and opposing effects of Asian ginseng (Panax ginseng C.A. Meyer) on acute glycemia: results of two acute dose escalation studies. J Am Coll Nutr. 2003;22(6):524–532.

Jafri MA, Aslam M, Javed K, Singh S. Effect of Punica granatum Linn. (flowers) on blood glucose level in normal and alloxan-induced diabetic rats. Journal of Ethnopharmacology 2000;70:309–314.

JL S, JT A, LA L, V V, V; V. Null and opposing effects of Asian ginseng (Panax ginseng C.A. Meyer) on acute glycemia: results of two acute dose escalation studies. J Am Coll Nutr. 2003;22(6):524–532.

Jarald E, Joshi SB, Jain DC. Diabetes and herbal medicines. Iranian Journal of Pharmacology and Therapeutics;2008(1):97–106.

Available from: https://www.ayurtimes.com/bgr-34-for- diabetes.

Rosalie IO, EL E. Antidiabetic potentials of common herbal plants and plant products: A glance. International Journal of Herbal Medicine;2016(4):90–97.

Ghorbani A. Best herbs for managing diabetes: A review of clinical studies.Brazillian. journal of pharmaceutical sciences;2013(49).

Wais M. Nazish I, Samad A, Beg S, Abusufyan S, Ajaz AS, Mohd Aqil. Herbal Drugs for Diabetic Treatment: An;.

Vijayalakshmi N. Anbazhagam M, Arumugam K. Medicinal plants for diabetes used by the people of Thiru Moorthy hills region of western ghats. International Journal of current microbiology and applied sciences;2014(3):405–410.

Nigam V, Nambiar VS. Therapeutic potential of aegle marmelos correa leaves as an antioxidant and antidiabetic agent: a review. International Journal of Pharma Sciences and Research2015;6(3);.

Elavarasi S. Saravanan K, Renuka C. A systematic review on medicinal plants used to treat diabetes mellitus. International journal of pharmaceutical, chemical and biological sciences;2013(3):983–992.




How to Cite

Sonia Verma, Madhu Gupta, Harvinder Popli, Geeta Aggarwal. Diabetes mellitus treatment using herbal drugs. ijp [Internet]. 2018 Mar. 31 [cited 2024 Jun. 21];10(1):1-10. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/583



Review Article