Gmelina arborea: chemical constituents, pharmacological activities and applications


  • Charu Arora Associate Professor and Head Department of Chemistry,Guru Ghasidas University, Bilaspur, CG, India
  • Vinita Tamrakar Research Scholar Department of Chemistry,Guru Ghasidas University, Bilaspur, CG, India


Gmelina arborea (G. arborea) is a bio-prospective plant belonging to family verbenaceae. It is widely used for it’s medicinal properties from ancient times. The present paper comprehensively reviewed the traditional uses, medicinal properties and chemical constituents isolated from G. arborea based on literature reported as well as critical analysis of the research. The present article is aimed to provide information on recent advances and new foundations and direction for further exploring G. arborea for its applications. Pharmacological research reviewed that G. arborea possess various medicinal properties and biological activities including antidiuretic, antidiarrhoeal, antipyretic, antianalgesic, antioxidant, antidiabetic, antihelmintic, antibacterial, antifungal, cardiopotective, insecticidal, antiulcer, gastro-protective, anticancer, antihyperlipidemic and immunomodulatory activity. It has been reported for its applications in treatment of bone fracture, hypertension and regeneration of β-cells. The main chemical constituents of G. arborea include lignans, iridoid glycoside, flavonoids, flavons, flavone glycoside and sterols. The present review provides all the references and beneficial directions to explore further application of G. arborea.


. Wang Z. Cultivation and utilization of

Gmelina arborea in South Yunnan,

China, New Forest, Netherlands. 2004;

: 201.

. Banu M, Gururaja GM, Deepak M,

Roopashree T, Shashidhara S. An

overview on Phytochemistry and

Pharmacological properties of Gmelina

arborea. J Nat Prod Plant Resour.

; 3; 62.

. Lauridsen EB, Kjaer ED. Provenance

research in Gmelina arborea Linn.

Roxb. A summary of results from three

decades of research and a discussion

of how to use them, International For

Rev. 2002; 4: 1.

. Evans J. Plantation forestry in the

tropics Clarendon press, Oxford, UK.

; 472.

. Jensen M. Trees commonly cultivated

in Southeast Asia, Illustrated field

guide. 38, FAO, Bangkok, Thailand.

; 93.

. Davidson J. Assistance to the forestry

sector of Bangladesh. Species and

sites-What to plant and where to plant.

Field Doc. No. 5,

UNDP/FAO/BGD/79/017. 1985; 50.

. Padua JM. Juvenile selection of

Gmelina arborea clones in the

Philippines, New Forest 2004; 28:195.

. Dvorak WS, World view of Gmelina

arborea: opportunities and challenges

New Forests New Forest. 2004; 28:

. Roquel RM, TomazelloFo M. Wood

density and fiber dimensions of

Gmelina arborea in fast growth trees in

Costa Rica: relation to the growth rate.

Investigación Agraria: Sistemas y

Recursos Forestales. 2007; 16: 267.

. El-Mahmood AM, Doughari JH, Kiman

HS, In vitro antimicrobial activity of

crude leaf and stem bark extracts of

Gmelina arborea (Roxb) against some

pathogenic species of

Enterobacteriaceae. Afr J Pharm

Pharmacol.,2010; 4: 355.

. Valsaraja R, Pushpangadana P, Smitt

UW, Adsersenb A, Nymanb U.

Antimicrobial screening of selected

medicinal plants from India. J

Ethnopharmacol. 1997; 58: 75.

. Idu M, Ovuakporie-Uvo PO, Ndana

RW. Preliminary Phytochemistry and In

Vitro Antimicrobial Properties of The

Chloroform and Ethanol Extracts of

The Roots of Cedrela Odorata,

Chlorophora Excelsa and Gmelina

Arborea. International journal of

Analytical, Pharmaceutical and

Biomedical Science (IJAPBS). 2015; 4:

. Kawamura F, Ohara S, Nishida A.

Antifungal activity of constituents from

the heartwood Gmelina arborea: part 1.

Sensitive antifungal assay against

Basidiomycetes, Holzforschung. 2004;




How to Cite

Charu Arora, Vinita Tamrakar. Gmelina arborea: chemical constituents, pharmacological activities and applications. ijp [Internet]. 2017 Dec. 31 [cited 2024 Jun. 23];9(4):528-42. Available from:



Review Article