Phytochemical Screening and Analgesic Activity of Opuntia ficus indica cladods extract in Wistar rats

Authors

  • Sihem HALMI Laboratory of Pharmacology and Toxicology, Institute of Veterinary Sciences, University of Mentouri Constantine1, Algeria.
  • Madi A Laboratory of Pharmacology and Toxicology, Institute of Veterinary Sciences, University of Mentouri Constantine1, Algeria.
  • Madi A Laboratory of Pharmacology and Toxicology, Institute of Veterinary Sciences, University of Mentouri Constantine1, Algeria.
  • Berouel K Laboratory of Pharmacology and Toxicology, Institute of Veterinary Sciences, University of Mentouri Constantine1, Algeria.
  • Lemoui R Research Unity : Valorization of natural resources, Bioactive Molecules and Physico-Chemical and Bilogical Analysis. University of Mentouri Constantine 1, Algeria.
  • Benlakssira B Laboratory of Pharmacology and Toxicology, Institute of Veterinary Sciences, University of Mentouri Constantine1, Algeria.
  • Hamdi pacha Y Laboratory of Pharmacology and Toxicology, Institute of Veterinary Sciences, University of Mentouri Constantine1, Algeria.

Keywords:

Extract, Phytochemical, Pain, Analgesic, Opuntia ficus indica

Abstract

The purpose of this work is the study of the peripheral and central analgesic activity of the Opuntia ficus indica cladods extract. Different concentrations are tested: 1000 mg/kg; 2000 mg/kg and 3000 mg/kg of body weight on rats by three different methods: the tail flick, the hot-plate and the writhing test to the acetic acid. The results obtained show that the aqueous extract of the cladods has an peripheral and central analgesic activity comparable to that of the Aspirin after administration to rats. The phytochemical analysis of the extract reveals the presence of tannins, coumarins, flavonoids, steroids and anthocyanins whose properties can be used to advantage in the treatment of pain. Our results confirm the traditional use of Opuntia ficus-indica cladods as an analgesic.

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Published

30-06-2016

How to Cite

1.
Sihem HALMI, Madi A, Madi A, Berouel K, Lemoui R, Benlakssira B, Hamdi pacha Y. Phytochemical Screening and Analgesic Activity of Opuntia ficus indica cladods extract in Wistar rats. ijp [Internet]. 2016 Jun. 30 [cited 2024 May 19];8(2):282-6. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/468

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