Identification of an antibacterial Withanolide (Dinoxin B) from leaf of Datura inoxia Mill.


  • Chandni Tandon Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow- 226028
  • Priti Mathur Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow- 226028.
  • Manodeep Sen Department of Microbiology, Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow- 226010 India.
  • Sanjeev Kanojiya Sophisticated Analytical Instrument Facility, CSIR-Central Drug Research Institute, Lucknow-226031


Datura inoxia, antibacterial compound, column chromatography, LC-ESI-MS, Withanolide


Natural medicines are gaining popularity due to the alarming incidence of bacterial resistance even in regions with improved healthcare systems. Hence, there is a distinct and constant need for isolating medicinally active compounds from different natural sources. Taking this into consideration, experiment was done in order to isolate and identify an antibacterial compound from Datura inoxia through bioassay and Mass spectroscopy technique. The ethanol, hexane and aqueous leaf extracts of Datura inoxia were screened for


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How to Cite

Chandni Tandon, Priti Mathur, Manodeep Sen, Sanjeev Kanojiya. Identification of an antibacterial Withanolide (Dinoxin B) from leaf of Datura inoxia Mill. ijp [Internet]. 2016 Mar. 31 [cited 2024 Apr. 24];8(1):1-12. Available from:



Original Research Articles