Traditional medicinal plants as anticancer agents from Chhattishgarh, India: An overview

Authors

  • Ritesh Jain SLT institute of Pharmaceutical Sciences, Guru Ghasidas Viswavidyalaya Bilaspur. Chhattisgarh, 495009.
  • Sanmati K. Jain SLT institute of Pharmaceutical Sciences, Guru Ghasidas Viswavidyalaya Bilaspur. Chhattisgarh, 495009.

Keywords:

Anticancer, Medicinal plant, Ethanobotanical, Chhattishgarh

Abstract

An attempt has been made to review some medicinal plants used for the prevention and treatment of cancer in Chhattisgarh. Information on the name of plants, family, parts used and method of preparation has been collected from Ethanobotanical literatures. Information collected has revealed 53 plants species that are used for treatment of cancer in Chhattisgarh. All these plants were further reviewed for scientific evidence, 33 plants out of 53 plants were found for possess anticancer, cytotoxic or antioxidant activity in various preclinical or clinical studies.

References

Akerele O. Medicinal plants and primary

health care: An agenda for action.

Fitoterapia. 1988;59: 355–63.

WHO, Regulatory situation of herbal

medicines, A worldwide review, Geneva,

Switzerland. 1998, 1–5.

Koduru S, Griersom DS , Afolayan AJ.

Ethnobotanical information of medicinal

plants used for treatment of cancer in the

Eastern Cape province, South Africa. Curr

Sci. 2007;92(2): 906-9.

American Cancer Society, A biotechnology

company dedicated to cancer treatment

[Internet] viewed on 2009, October 21,

available From:

www.cancervax.com/info/index.htm.

Balachandran P, Govindrajan R. Cancer-an

ayurvedic perspective. Pharmacological

research. 2005;51: 19-30.

Mukherjee AK, Basu S, Sarkar N, Ghosh

AC. Advances in cancer therapy with plants

based natural products. Current medicinal

chemistry. 2001; 8: 1467-86.

Madhuri S , Pandey G. Some anticancer

medicinal plants from foreign origin.

Current Science. 2009; 96 (6): 779-83.

Hartwell JL, Plants used against cancer. A

survey. Lloydia. 1969; 32: 247–96.

Hartwell JL, Plants used against cancer. A

survey. Lloydia. 1969; 32:153–205.

Hartwell JL, Plants used against cancer. A

survey. Lloydia. 1971; 34: 103–50.

Pandey G. Anticancer herbal drugs of India

with special reference to Ayurveda. New

Delhi: Sri Satguru Publications. 2002; 18–

Cragg GM, Newman DJ. Plants as a source

of anti-cancer agents, In

ethanopharmacology. Eds. Elisabetsley E.

Etkin NL. in Encyclopedia of life support

system (EOLLSS), Eloss Publisher, oxford,

UK.

Traditional Medicinal Knowledge about

Herbs used in Treatment of Cancer in

Chhattisgarh, India. Interactions with Senior

Traditional Healers, (Internet) Cited on

, October 22, Available from:

http://botanical.com/site/column_poudhia/p

ublish/journal.cgi?folder=journal&next=11

Traditional Medicinal Knowledge about

Herbs used in Treatment of Cancer in

Chhattisgarh, India. Herbs for Cancerous

Wounds, (Internet) cited on 22

October2009, Available from:

http://botanical.com/site/column_poudhia/p

ublish/journal.cgi?folder=journal&next=11

Overview of Chhattisgarh. (Internet) Cited

on 22 October 2009, Available from:

http://chips.nic.in/content/chhattisgarh.htm.

Scope for organic farming in Chhattisgarh:

an Indian perspective, (Internet) Cited on 22

October 2009. Avalble from:

http://www.inra.fr/ciab/papers/RaoJACS.pd

f.

Jadhav D. Medicinal plants of

Madyapradesh and Chhattisgarh. Daya

publishing house, New delhi ,India. 2006;

-112.

Tiwari RKS, Ojha BM, Singh A & Sahu

SK. Medicinal plants of Chhattisgarh.

Published by Agriculture collage and

research center, Bilaspur. Pub. No.

TCBCARS/Technical Bulletin/06-07/01.

Medicinal plants of Dantewada district,

Chhattisgarh. (Internet), Cited on 22 oct.

, available from:

http://www.dantewada.nic.in/medi2.htm.

Subbareddy VV, Sirsi M. Effect of Abrus

precatorius Linn. On experimental tumours,

Cancer Res, 1969;29: 1447–51.

Arora S, Kaur K, Kaur S. Indian medicinal

plants as a reservoir of protective

phytochemicals. Teratog Carcinog

Mutagen. 2003;23: 295 – 300.

Jahangir T, Sultana S. Tumor Promotion

and Oxidative Stress in Ferric

Nitrilotriacetate-Mediated Renal

Carcinogenesis: Protection by Adhatoda

vasaca. Toxicol Mech Methods. 2007;17

(7): 421-30.

Leticia VCL. Studies of the anticancer

potential of plants used in Bangladeshi folk

medicine. J Ethnopharmacol. 2005; 99 (1):

-30.

Jagetia GC, Venkatesh P , Baliga MS.

Aegle marmelos (L.) Correa Inhibits the

proliferation of transplanted ehrlich ascites

carcinoma in mice. Biol. Pharm. Bull,

;28(1): 58-64.

Dhar ML, Dhar MM, Dhawan BN,

Mehrotra BN, Ray C. Screening of Indian

plants for biological activity. Part-I. Indian

J Exp Biol. 1968;6 :232–47.

Pawar RS, Jain AK, Kashaw SK , Singhai

AK. Haemaatopoiteic activity of

Asteracantha longifolia on

cyclophasphamide-induced bone marrow

suppression. Indian J. Pharm. Sci. 2006;68

(3): 337-340.

Ahmed S, Rahman A, Mathur M, Athar

M , Sultana S. Anti-tumor promoting

activity of Asteracantha longifolia against

experimental hepatocarcinogenesis in rats.

Food Chem Toxicol. 2001; 39 (1): 19-28.

Gnoula C, Mégalizzi V, De Nève N,

Sauvage S, Ribaucour F, Guissou P et al.

Balanitin-6 and -7: diosgenyl saponins

isolated from Balanites aegyptiaca Del.

display significant anti-tumor activity in

vitro and in vivo. Int J Oncol. 2008; 32(1):

-15.

Rajkapoor B, Jayakara B , Murugesh N.

Antitumour activity of Bauhinia variegata

on Dalton’s ascitic lymphoma. J

Ethnopharmacol. 2003; 89(1) : 107-9.

Sehrawat A, Sultana S. Chemoprevention

by Butea monosperma of hepatic

carcinogenesis and oxidative damage in

male wistar rats. Asian Pac J Cancer Prv..

; 7(1): 140-8.

Bhakuni DS, Dhar ML, Dhar MM, Dhawan

BN, Mehrotra BN. Screening of Indian

plants of biological activity, Part-II. Indian

J Exp Biol. 1969;7: 250–62.

Contassot E, Tenan M, Schnuriger V, Pelte

MF, Dietrich PY. Arachidonyl

ethanolamide induces apoptosis of uterine

cervix cancer cellsvia aberrantly expressed

vanilloid receptor-1. Gynecol Oncol.

;93:182–8.

Gupta M, Mazumder UK, Rath N,

Mukhopadhyay DK. Antitumor activity of

methanolic extract of Cassia fistula L.seed

against Ehrlich Ascites Carcinoma. J

Ethnopharmacol, 2000; 72: 151-6.

Tian Q, Miller EG, Ahmad H, Tang L,

Patil BS. Differential inhibition of human

cancer cell proliferation by Citrus

limonoids. Nutr Cancer. 2001; 40: 180-4.

Poulose SM, Harris ED, Patil BS, Citrus

limonoids induce apoptosis in human

neuroblastoma cells and have radical

scavenging activity. J Nutr. 2005; 870-8.

Josefina CE, Sandra GA, Rafael VP, Jesús

JEA. Antimutagenicity of coriander

(Coriandrum sativum) juice on the

mutagenesis produced by plant metabolites

of aromatic amines. Toxicol Lett. 2004;153

(2): 283-92.

Aggarwal BB, Kumar A, Bharti AC.

Anticancer potential of curcumin:

preclinical and clinical studies. Anticancer

Res. 2003; 23 ; 363-98.

Shrinath NPI, Premalatha B. Dietary

curcumin with cisplastin administration

modules tumour marker enzymes indices in

experimental fibrosarcoma. Pharmacol Res.

; 39: 175-9.

Jose JK, Kuttan G, Kuttan R. Antitumour

activity of Emblica officinalis. J

Ethnopharmacol. 2001;75 (2-3): 65-9.

Smit HF, Woerdenbag HJ, Singh RH,

Meulenbeld GJ, Abadie RP, Waving JH.

Ayurvedic herbal drugs with possible

cytostatic activity. J Ethnopharmacol.

; 47: 75-84.

Kamuhabwa A, Nshimo C, Witte PD.

Cytotoxicity of some medicinal plant

extracts used in Tanzanian traditional

medicine. J Ethnopharmacol, 2000;70:

–9.

Olaleye MT. Cytotoxicity and antibacterial

activity of Methanolic extract of Hibiscus

sabdariffa. J Medicinal Plants Research.

;1(1): 9-13.

Percival SS, Talcott ST, Chin SR, Mallak

AC, Lounds SA, Pettit MJ. Neoplastic

transformation of BALB/3T3 cells and cell

cycle of HL-60 cells are inhibited by mango

(Mangifera indica L.) juice and mango

juice extracts, J Nutr. 2006;136 (5): 1300-

Takeya K, Qiao ZS, Hirobe C, Itokawa H.

Cytotoxic trichilin-type limonoids from

Melia azedarch. Bioorg Med Chem. 1996;4

(8): 1355-9.

Dhawan BN, Dubey MP, Mehrotra BN,

Rastogi RP, Tandon JS. Screening of Indian

Plants for biological activity, part-IX.

Indian J Exp Biol. 1980;18: 594-606.

Bharali R, Tabassum J, Azad MRH.

Chemomodulatory effect of Moringa

oleifera, Lam, on hepatic carcinogen

metabolizing enzymes, antioxidant

parameters and skin papillomagenesis in

mice. Asian Pac J Cancer Prev.

;4:131-9.

Guevara AP, Vargas C, Sakurai H, Fujiwara

Y, Hashimoto K, Maoka T et al. An

antitumor promoter from Moringa oleifera

Lam. Mutat Res. 1999;440: 181-8.

Yerra R, Gupta M, Mazumder KU.

Antitumor Activity and in vivo Antioxidant

Status of Mucuna pruriens (Fabaceae) seeds

against Ehrlich Ascites Carcinoma in Swiss

Albino Mice. Iran J Pharmacol Therap.

; 4 (1): 46-53.

Pathak S, Multani AS, Narayan S, Kumar

V , Newman RA, Anvirzel TM. An extract

of Nerium oleander, induces cell death in

human but not murine cancer cells.

Anticancer Drugs. 2000;11(6): 455-63.

Dubey NK. Cytotoxicty if the essential oil

of Cymbogon citrus and Ocimum

grattissimum, Indian j Pharm Sci. 1997;59:

-9.

Kartikeyan K, Gunasekaran P, Ramamurthy

N, Govindasamy S. Anticancer activity of

Ocimum sanctum. Pharm Biol. 1999;37(4):

-90.

Panda S, Yadav R. Plants with anticancer

activity: need for in vitro study. Vaniki

Sandesh. 2005;29 (1): 32-4.

Darmanin S, Wismayer PS, Podesta MTC,

Micallef MJ, Buhagiar JA. An extract from

Ricinus communis L. leaves possesses

cytotoxic properties and induces apoptosis

in SK-MEL-28 human melanoma cells. Nat

Prod Res, 2009;23 (6): 561-71.

Varghese CD, Nair SC, Panikkar KR.

Potential anticancer activity of Saraca

asoca extracts towards transplantable

tumours in mice. Indian j Pharm Sci.

;54 (1) : 37-40.

Balachandran P, Vallinayagam M,

Panchanatham S. Anticancer potency of the

milk extract of Semecarpus anacardium

Linn. nuts against aflatoxin B1 mediated

hepatocellular carcinoma bearing wistar rats

with reference to tumour marker enzymes.

Phytother Res. 1999;13 (3): 183 -7.

Ramos A, Visozo A, Piloto J, Garcıa A,

Rodrıguez CA, Rivero R. Screening of

antimutagenicity via antioxidant activity in

Cuban medicinal plants. J Ethnopharmacol.

; (87):241-6.

Al-Fatimi M, Wurster M, Schroder G &

Lindequist U. Antioxidant, antimicrobial

and cytotoxic activities of selected

medicinal plants from Yemen. J

Ethnopharmacol. 2007;111: 657–66.

Sarveswaran S, Muthaiyan I,

Balasubramanian MP. Anticancer potency

of Terminalia arjuna bark on Nnitrosodiethylamine-induced hepatocellular

carcinoma in rats. Nat Prod Sci. 2004;10

(4):190-5.

Kandil FE, Nassar MI. A tannin anti-cancer

promotor from Terminalia arjuna,

Phytochemistry. 1998;47(8): 1567-8.

Kaura K, Aroraa S, Kumarb S, Nagpala A.

Antimutagenic activities of acetone and

methanol fractions of Terminalia arjuna.

Food Chem Toxicol. 2002;40: 1475-82.

Saleem A, Husheem M, Harkonen P,

Pihlaja K. Inhibition of cancer cell growth

by crude extract and the phenolics of

Terminalia chebula retz. Fruit. J

Ethnopharmacol. 2002;81: 327-36.

Kaur S, Arora S, Kaur K, Kumar S. The in

vitro antimutagenic activity of Triphala - an

Indian herbal drug. Food Chem Toxicol.

;40 (4): 527-34.

Kaur S, Grover IS, Singh M, Kaur S.

Antimutagenicity of hydrolyzable tannins

from Terminalia chebula in Salmonella

typhimurium. Mutat Res. 1998;419:169–79.

Prasad L, Khan TH, Jahangir T, Sultana S.

Chemo-modulatory effects of Terminalia

chebula against nickel chloride induced

oxidative stress and tumor promotion

response in male Wistar rats. J Trace Elem

Med Biol. 2006;20: 233–9.

Kapil A, Sharma S. Immunopotentiating

compounds from Tinospora cordifolia. J

Ethnopharmacol. 1997;58: 89–95.

Jagetia GC, Rao SK. Evaluation of the

antineoplastic activity of Guduchi

(Tuinospora cardifolia) in ehrlich ascites

carcinoma bearing mice. Biol Pharm Bull.

;29 (3): 460-6.

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Published

30-09-2010

How to Cite

1.
Ritesh Jain, Sanmati K. Jain. Traditional medicinal plants as anticancer agents from Chhattishgarh, India: An overview. ijp [Internet]. 2010 Sep. 30 [cited 2024 Dec. 23];2(3):186-9. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/37

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