A new 4’,6-dihydroxy,4-methoxybenzophenone-2-O-β-D-gentiobioside and 4’,6-dihydroxy,4 methoxybenzophenone-2-O-β-D-glucoside isolated from methanolic extract of Phaleria macrocarpa (Scheff.) Boerl leaves

Authors

  • Yosie Andriani Institute of Marine Biotechnology, University Malaysia Terengganu, Terengganu, Malaysia and Bengkulu University, Bengkulu, Indonesia Malaysia
  • Effendy AWM Institute of Marine Biotechnology, University Malaysia Terengganu, Terengganu, Malaysia and Bengkulu University, Bengkulu, Indonesia Faculty Science and Technology, University of Malaysia Terengganu (UMT), Terengganu, Malaysia. Indonesia
  • Tengku Sifzizul Tengku Muhammad Institute of Marine Biotechnology, University Malaysia Terengganu, Terengganu, Malaysia and Bengkulu University, Bengkulu, Indonesia Faculty Science and Technology, University of Malaysia Terengganu (UMT), Terengganu, Malaysia. Indonesia
  • Habsah M Institute of Marine Biotechnology, University Malaysia Terengganu, Terengganu, Malaysia and Bengkulu University, Bengkulu, Indonesia Faculty Science and Technology, University of Malaysia Terengganu (UMT), Terengganu, Malaysia.
  • Jalifah Latip Faculty Science and Technology, University Kebangsaan Malaysia, Bangi-Selangor,Malaysia

Keywords:

Phaleria macrocarpa, phalerin, methoxybenzophenone, gentiobioside, SR-B1

Abstract

A new 4’,6-dihydroxy,4-methoxybenzophenone-2-O-β-D-gentiobioside (1) was obtained from the leaves of Phaleria macrocarpa (Scheff.) Boerl along with known 4’,6-dihydroxy,4-methoxybenzophenone-2-O-β-D-glucoside (2). Bioactivity assays indicated that compound (1) and (2) have antioxidant activity and enhancement on SR-B1 genes expression in vitro. Their structures compounds were established by the interpretation of their spectroscopic data and comparison with known compounds.

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Published

31-03-2014

How to Cite

1.
Yosie Andriani, Effendy AWM, Tengku Sifzizul Tengku Muhammad, Habsah M, Jalifah Latip. A new 4’,6-dihydroxy,4-methoxybenzophenone-2-O-β-D-gentiobioside and 4’,6-dihydroxy,4 methoxybenzophenone-2-O-β-D-glucoside isolated from methanolic extract of Phaleria macrocarpa (Scheff.) Boerl leaves. ijp [Internet]. 2014 Mar. 31 [cited 2024 Nov. 22];6(1):63-72. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/302

Issue

Vol. 6 No. 1 (2014): Jan-Mar

Section

Original Research Articles