A Comprehensive Ethno-Phyto-Pharmacological Review on Novel Indian Medicinal Plants Used In Polyherbal Formulations

Authors

  • Pulak Majumder PRIST University India Research Scholar, CRD, PRIST University
  • Paridhavi M RGIP, Tikaripur,Kerala. India

Keywords:

Medicinal Plants, Ethanomedical Use, Phytochemistry, Pharmacological Sereening

Abstract

Almost 15% out of the 20,000 medicinal plants in Indian sub continent has a tremendous potential and advantage in the emerging field of herbal medicines. Medicinal plants are the main sources of chemical substances with potential therapeutic effects. A lot of compounds were characterized from plants which are now using in the treatment of many diseases. Since ancient times, plants have been an exemplary source of medicine. Ayurveda and other Indian literature mentioned the use of plants in treatment of various human ailments. Medical plants play an important role in the management of different clinical problems especially in developing countries where resources are meager The present paper reviews the literature on recent ethno medicinal uses with pharmacological screeing of every plant part of different five medicinal plants, i.e Cassia Auriculata Linn, Cinnamomum tamala, Ficus benghalensis, Trichosynthes dioica and Mangifera indica and their phytochemical properties used for the treatment of various ailments in human civilization as well as used in folk medicine as a remedy. The name and parts of the plant studied, the spectrum of activity, and methods used are discussed in this review paper.

References

. Prakasha HM, Krishnappa M,

Krishnamurthy YL, Poornima SV. Folk

medicine of NR PuraTaluk in

Chikamaglur district of Karnatka.Indian

Journal of Traditional Knowledge 2010;

(1):55-60.

. World Health Organization. Guidelines

for the Assessment of Herbal Medicine

Programme on Traditional

Medicine.Doc. WHO/TRM/91.4.WHO,

Geneva, 2003.

. Biswas K, chattopadhyay I, Banerjee RK

& Bandyopadhyay U. Biological activities

and medicinal properties of neem

(Azadirachta indica). Curr sci. 2002;

:1336.

. Bandopadhyay U, Biswas K, Chatterjee

R, Bandopadyay D, chattopadhyay I,

Ganguly C K, Chakraborty T,

Bhattacharya K, & Banerjee RK.

Gastroprotective effect of

Neem(Azadirachta indica) bark extract:

possible involvement of H+-K+-ATPase

inhibition and scavenging of hydroxyl

radical. Life sci. 2002; 71: 2845.

. Grover JK, Yadav S, Vats V. Medicinal

plants of India with antidiabetic potential.

J Ethnopharmacol. 2002; 81:81-100.

. Edwards DM. The marketing of nontimber forest products from the

Himalayas: The Trade between East

Nepal and India. In: Rural Development

Forestry Network (Overseas

Development Institute, London) Paper.

; 15b:1-21

. S. T. Chang and S. S. Cheng.

Antitermitic activity of leaf essential oils

and components from Cinnamomum osmophleum. Journal of Agricultural and

Food Chemistry. 2002; 50(6):1389ă92.

. S. Nautiyal and H. Kaechele. Adverse

impacts of pasture abandonment in

Himalayan protected areas: testing the

efficiency of a natural

resourcenmanagement plan (NRMP).

Environmental Impact Assessment

Review. 2007; 27(2):109ă25.

. Gaur, R.D. Traditional dye yielding

plants of Uttarakhand, India. Natural

Products Radiance, 2008; 27(2): 154-65

. Chao LK, Hua K-F, Hsu H-Y, et al. Study

on the antiinflammatory activity of

essential oil from leaves of

Cinnamomum osmophloeum. J Agric

Food Chem. 2005; 53: 7274-8.

. Jayaprakasha GK, Rao LJ, Sakariah KK.

Volatile constituents from Cinnamomum

zeylanicum fruit stalks and their

antioxidant activities. J Agric Food

Chem. 2003; 51: 4344-8

. Nath SC, Baruah A, Hazarika AK.

Essential oils of leaves of Cinnamomum

Schaeffer members. Ind perfumer. 1999;

: 182-90

. Chanotiya CS, Yadav A.

Enantioenriched (3S)-(+)-Linalool in the

Leaf Oil of Cinnamomum tamala Nees et

Eberm. from Kumaon. J Essential Oil

Res. 2010: 22: 593

. Suresh Kumar, Sunil Sharma, Neeru

Vasudeva. Chemical compositions of

Cinnamomum tamala oil from two

different regions of India. Asian Paci J

Trop Dis.2012; S761- 4

. Mollenbeck S, Konig T, Schreier P, et al.

Chemical composition and analysis of

enantiomers of essential oils from

Madagascar. Flavour Fragrance J.1997

;12: 63-9

. J. Rema, N.K. Leela, B. Krishnamoorthy,

P.A. Mathew. Chemical composition of

Cinnamomum tamala essential oil- A

review. Journal of Medicinal and

Aromatic Plant Sciences. 2005; 27: 515-

. Roux GF, Perrier J, Forest E, Mouren

GM, Puigserver A, and Santimone M.

Screening of bark of Cinnamomum

tamala (Lauraceae) by using aamylase

inhibition assay for anti-diabetic activity.

Biochim Biophys Acta. 1998;1388: 10-20

. Usha Chakraborty, Hariswami Das.

Antidiabetic and Antioxidant Activities of

C.tamala Leaf Extracts in Stz-Treated

Diabetic Rats . G J Biotech Biochem.

; 5 (1):12-8.

. Shradha Bisht, S.S Sisodia. Assessment

of antidiabetic potential of cinnamomum

tamala leaves extract in streptozotocin

induced diabetic rats. Ind J Pharmacol.

; 43(5). 582-5.

. Rahul Gupta, Pramod Kumar Agnihotri,

Samta Johri And Anand Murari Saxena.

Hypoglycaemic Activity of Ethanol

Extract of Cinnamomum tamala Leaves

in Normal and Streptozotocin Diabetic

Rats. Iran J Pharmacol & Therapeutics.

; 8:17-21.

. Palanisamy P, K.R. Srinath, D.

Yoganand Kumar, Pooja Chowdary C.

Evaluation of antioxydent and ant

diabetic activity of cinnamomum tamala

Linn leaves in Streptozotocin induced

diabetic rats. Int Res J Pharm. 2011; 2

(12): 157-62.

. Prabuseenivasan S, Jayakumar M,

Ignacimuthu S. In vitro antibacterial

activity of some plant essential oils.

BMC Compl & Alter Med.2006; 6: 39

. Jamiuddin Ahmed, Nasrin Sultana, Syed

M. R. Dewan, Mohammad N Amin, S. M.

Naim Uddin. Determination of Chemical

Groups and Investigation of

Anthelmintic, Cytotoxic, and

Antibacterial Activities of Leaves of

Cinnamomum Tamala (Family:

Lauraceae). Int J Pharmamedix Ind.

; 1(2): 222-32.

. Osawa T and Namaki M. A novel type

antioxidant isolated from leaf wax of

Eucalyptus leaves. Agric Biol Chem.

; 45: 735-9.

. Miller NJ and Rice- Evans CA. Factors

affecting the antioxidant activity

determined by ABTS+ radical cation

assay. Free Radic Res. 1997; 26: 195-9

. Durre Shahwar, Shafiq-ur-Rehman,

Naeem Ahmad. Antioxidant activities of

the selected plants from the family

Euphorbiaceae, Lauraceae, Malvaceae

and Balsaminaceae. Afri J Biotech.2010;

(7): 1086-96

. Devi SL, Kannappan S, Anuradha CV.

Evaluation of in vitro antioxidant activity

of Indian bay leaf, Cinnamomum tamala

(Buch. -Ham.) T. Nees & Eberm using

rat brain synaptosomes as model

system. Ind J Exp Biol. 2007; 45(9):778-

. Lima ZP, Severi JA, Pellizzon CH, Brito

AR, Solis PN.Gastroprotective activity of

Cinnamomum tamala leaves on

experimental gastric ulcers in rats. J.

Ethnopharmacol. 2010; 128: 537-40

. Vardar Unlu G, Candan, Sokmen A,

Domez Eand Tepe B. Antimicrobial

activity of essential oil from C. tamala

(Lauraceae). J Agric Food Chem.2003;

: 63-7

. Manindra Mohan, S. Zafar Haider,

Akash Sharma, Richa Seth and Mithun

Sharma. Antimicrobial activity and

composition of the volatiles of

Cinnamomum tamala Nees. and

Murraya koenigii (L.) Spreng. from

Uttarakhand (India). Asian Paci J Trop

Dis. 2012; S324-7

. Hemayet Hossain, Md. Sariful Islam

Howlader, Shubhra Kanti Dey, Arpona

Hira, et al,. Evaluation of antiinflammatory activity of cinnamomum

tamala (buch.-ham.) Leaves growing in

bangladesh. Int J pharmaschol. 2012; 1

(2): 114-21

. Manmeet S Saluja, B Sangameswaran,

Ajay Sharma. Cytotoxic activity of

cinnamomum tamala linn. Against

ehrlich ascites Carcinoma (eac) in mice.

T. Ph. Res. 2010; 3: 232-42.

. Gambhire MN, Juvekar AR, Wankhede

SS. Anti-inflammatory activity of

aqueous extract of Cinnamomum tamala

leaves by in vivo and in vitro methods. J

Ph Res. 2009; (2) 9: 1521- 4.

. Thamizhselvam N, Soumya S,

Sanjayakumar YR, Salinichandran K,

Venugopalan TN, Jaya N. AntiInflammatory, Analgesic And Antipyretic

Activity Of Methanolic Extract Of

Cinnamomum Tamala (Nees) In

Experimental Animal Models. Int J

Bioas, 2012; 01 (09): 26ă9.

. G.V. Manjunatha Reddy, R. Girish

GKVK, M. S. Uma, N. Srinivas.

Acaricidal activity of aqueous extracts

from leaves and bark of cinnamomum

and jatropha against two spotted spider

mite, Tetranychus urticae Koch.

Karnataka. J. Agric. Sci. 2009; 22(3) :

-5

. Ritu Singh, Amit Kumar Singh,

Akanksha Soam, Sushil Kumar Shahi.

Antifungal screening of various spice

extracts on azole resistant strains of

Candida. Int J Curr Disc and innov.

; 2(1): 46-52

. Bhawana Srivastava, Anand Sagar, N.

K. Dubey. Evaluation of Cinnamomum

tamala Oil and Its Phenylpropanoid

Eugenol for Their Antifungal and

Antiaflatoxigenic Activity. Food

Analytical Methods. 2011; 4 (3): 347-56

. Varsha Dhulasavant, Shubhangi Shinde,

Mangesh Pawar and N.S. Naikwade

Antihyperlipidemic activity of

Cinnamomum tamala Nees. on high

cholesterol diet induced hyperlipidemia.

Int J Ph & Life Sci. 2011; 2(1):506-10

. Md. Hemayet Hossain, Md. Sariful Islam

Howlader, Shubhra Kanti Dey et al,.

Evaluation of Antidiarrhoeal,

Antimicrobial and Cytotoxic Activities of

Cinnamomum Tamala Leaves from

Bangladesh. Int J Pharm. 2012; 2(4):

-6.

. Chandana Venkateswara Rao,

Madhavan Vijayakumar, K. Sairam,

Vikas Kumar. Antidiarrhoeal activity of

the standardised extract of

Cinnamomum tamala in experimental

rats. J Nat Med. 2008; 62 (4): 396-402

. Rao CV, Vijayakumar M, Sairam K,

Kumar V. Antidiarrhoeal activity of the

standardised extract of Cinnamomum

tamala in experimental rats. J Nat Med.

; 4(62): 396-402.

. Al-Mamun R, Hamid A, Islam MK,

Chowdhury JA and Zafrul Azam ATM.

Lipid Lowering Activity and Free Radical

Scavenging Effect of Cinnamomum

tamala (Fam: Lauraceae). Int J Nat Sci.

; 1(4):93-6

. Eswaran MB, Surendran S, Vijayakumar

M, Ojha SK, Rawat AKS, Rao CV.

Gastroprotective activity of

Cinnamomum tamala leaves on

experimental gastric ulcers in rats. J

Ethnopharmacol. 2010; 128: 537-40.

. Siva, R. and K.V. Krishnamurthy.

Isozyme diversity in Cassia auriculata L,

Afri J Biotechnol. 2005; 4: 772-5.

. SG Joshi, Cesalpinaceae- Cassia

auriculata, Textbook of Medicinal Plants,

third ed. India Book House, Bangalore,

. KV Ratnam, RRV Raju, Ind J Trad

Knowledge. 2005; 4: 267-70.

. GM Jeeva, S Jeeva, C Kingston, Ind J

Trad Knowledge. 2007; 6: 498-501.

. C Kingston, S Jeeva, S Kiruba, BP

Mishra, D Kannan, Ind J Trad

Knowledge. 2009; 8: 196-200.

. KV Ratnam, RRV Raju, Ind J Trad

Knowledge. 2008; 7: 436-7.

. S Nagnur, G Channal, N Channamma,

Ind J Trad Knowledge. 2009; 8:577-80.

. S Ganesan, S Ponnuchamy, S Kesavan,

A Selevaraj. Ind J Trad Knowledge.

; 8:154-200.

. C Muthu, M Ayyanar, M Raja, M

Ignacimuthu. J Ethnobiology and

Ethnomedicine. 2006; 2: 1-10.

. S Ganesan, M Chandhirasekaran, A

Selevaraj, Ind J Trad Knowledge. 2008;

: 347-54.

. BS, Sandhya, W Thomus, Isabel, R

Shenbagarathai. Afri J Trad, Compl,

and Alt Med. 2006; 3:101-14.

. K Rajendran, P Balaji, MJ Basu, Ind J

Trad Knowledge. 2008; 7: 417-20.

. Nageswara Rao, Mahesh Kumar P, VS

Dhandapani, Toshimitsu Hayashi.

Constituents of Cassia auriculata,

Fitoterapia.2000; 71: 82-3.

. A. Anandan, R. Eswaran, A.Doss, G.

Sangeetha and S. P. Anand. Chemical

Compounds Investigation of Cassia

auriculata Leaves ă APotential Folklore

Medicinal Plant. Bulletin of Environment,

Pharmacol & Life Sci. 2011; 1(1): 20-3.

. J. Yesu Raj, M. Paul John Peter, V. Joy.

Chemical compounds investigation of

Cassia auriculata seeds: A potential

folklore medicinal plant. Asian J Plant

Sci and Res. 2012; 2 (2):187-92

. Juan-Badaturuge M, Habtemariam S,

Thomas MJK. Antioxidant compounds

from a South Asian beverage and

medicinal plant, Cassia auriculata. Food

Chem.2011; 125: 221ă5.

. L Pari, M Latha Effect of Cassia

Auriculata Flowers on Blood Sugar

Levels, Serum and Tissue Lipids in

Streptozotocin Diabetic Rats. Singapore

Med J. 2002; 43(12) : 617-21

. Mahendra Shiradkarg, Pawankumar and

kapil shah. Pharmacological Evaluation

of Cassia Auriculata Bark Extract. Int J

Pharma and Bio Sci. 2011; 2 (1): 758-66

. Jeeva Jothi Dhanasekaran ; Mathangi

Ganapathy. Hepatoprotective Effect of

Cassia auriculata L. Leaf Extract on

Carbon Tetrachloride Intoxicated Liver

Damage in Wister Abino rats. Asian J

Biochem. 2011; 6 (1):104-12

. S. Maneemegalai and T. Naveen.

Evaluation of Antibacterial Activity of

Flower Extracts of Cassia auriculata

L.Ethnobotanical Leaflets. 2010; 14:

- 92

. C. Anushia, P. Sampathkumar and L.

Ramkumar. Antibacterial and

Antioxidant Activities in Cassia

auriculata. Global J Pharmacol. 2009; 3

(3): 127-30

. Gaurav M. Doshi, Supriya S. Shidhaye,

Gayatri V. Aggarwal, Preeja P. Pillai.

Antibacterial potential of Cassia

auriculata flowers. J. Microbiol. Biotech.

Res., 2011; 1 (3): 15-9.

. Vedavathy, S. and Rao, K.N. Antipyretic

activity of six indigenous medicinal

plants of Tirumala hills, J

Ethanopharmacol. 1991;33: 193-6.

. Kumaran, A., Joel Karunakaran, R.

Antioxidant activity of Cassia auriculata

flowers, Fitoterapia. 2007;78: 46-7

. PS Kumar, S Sucheta, VS Deepa, P

Selvamani, S Latha., Antioxidant activity

in some selected Indian medicinal

plants. Afri J Biotech. 2008; 7(12).

. Satish B. Kosalge, Ravindra A. Fursule.,

Investigation of anthelmintic potential of

some plants claimed by tribals of

satpuda hills. Int J Pharm Tech

Res.2009;1(1): 68-72

. P. Salvekar. Anthelmintic activity of

Cassia auriculata L. extracts-In vitro

study. Scholars Research Library J. Nat.

Prod. Plant Resour. 2011; 1(2): 62-6

. Sushma Kainsa, Praveen Kumar,

Randhir Singh Dahiya. Investigation of in

vitro anthelmintic activity of Cassia

auriculata leaves. J. Nat. Prod. Plant

Resour.2012; 2 (4):460-4.

. Senthil Kumar, Rajagopal Ponmozhi,

Manickam Viswanathan ,Periyasamy

Nalini Namasivayam Activity of Cassia

auriculata leaf extract in rats with

alcoholic liverinjury. T J Nutri

Biochem.2003; 14(8): 452ă8.

. Ahmed M, Rao SA, Thayyil HA, Ahemad

RS, Abid M, Ibrahim M. antiulcer activity

of leaf extract of Cassia auriculata.

Pharmacog J. 2010;2(16):48-52

. H. M. Suresh, B. C. Hatapakki, S. I.

Shivakumar, C. S. Hallikeri, B. M.

Swamy, V. K. Chandur. J Nat Rem.

; 7(1): 150 ă 4

. V.V. Shivrajan. Ayurvedic drugs and

their Plant sources. Oxford and IBH

Publishing Company Pvt. Ltd. New

Delhi; 2002.p.333

. Prajapati, Purohit, Sharma and Kumar.

A handbook of Indian medicinal plants a

complete source book; 2005. p. 237

. A. Chatterjee. The treaties of Indian

medicinal plants: Vol.I; 1997. P. 39

. Chopra R. N., Chopra I.C. Handa K.L.

and Kapur L.D. Indigenous drugs of

India, U.N.Dhur and sons Pvt. Ltd.

Calcutta; 1958. p.673- 5

. Medicinal plants of India, ICMR, New

Delhi, vol.I; 1956. p.415-6.

. C.P. Khare. Encyclopedia of Indian

Medicinal Plants. Springer publication;

P. 216-7

. Rimi Shukla, Shweta Gupta , J.K.

Gambhir , K.M. Prabhu , P.S. Murthy.

Antioxidant effect of aqueous extract of

the bark of Ficus bengalensis in

hypercholesterolaemic rabbits. J

Ethnopharmacol. 2004; 92: 47ă51

. Subramanian PM, Misra GS. Chemical

constituents of Ficus bengalensis (Part

II). Pol J Pharmacol Pharm. 1978;

(4):559-62

. Sheeja Cherian, Vinod Kumar, R. and

Augusti, K.T. (1992) Antidiabetic effect

of glycoside from Pelargonidin isolated

from the bark Ficus bengalensis Linn.

Ind. J. Biochem. Biophys. 1992;29: 380 -

. The Wealth of India, Volume-(F-G). In: A

Dictionary of Indian Raw Materials and

industrial products. Vol. 4. New Delhi:

Council of Scientific and Industrial

Research;1999. p. 24-6

. Kumar RV, Augusti KT, Insulin sparing

action of a leucocynidin derivative

isolated from Ficus bengalensis Linn.

Ind J Biochem and Biophy. 1994; 31:73-

. Daniel RS, Devi KS, Augusti KT

Mechanism of action of Antiatherogenic

and related effects of Ficus bengalensis

Linn. Flavonoids in experimental

animals. Ind J Exp Bio. 2003; 41:296-

. Geetha BS, Mathew BC, Augusti KT,

Hypoglycemic effects of

Leucodelphinidin derivative isolated from

Ficus bengalensis Ind J Physiol.

Pharmacol. 1994; 38(3):220.

. Augusti KT Hypoglycemic action of

bengalenoside: Aglucoside isolated from

Ficus Bengalensis Linn, in normal and

Alloxan diabetic rabbits. Ind J Physiol

Pharmacol. 1975; 19:218-20

. Augusti K T, Daniel RS, Cherian S,

Sheela CG,Nair CR Effect of

Leucopelargonin derivative from Ficus

bengalensis Linn on diabetic dogs. Ind J

Med Res. 1994; 82-6

. Cherian S, Sheela and Augusti K T

Insulin sparing action of

Leucopelargonin derivative solated from

Ficus bengalensis Linn. Ind J Exp Bio.

;33:608-11.

. Vikas VP, Vijay RP. Ficus bengalensis.

An Overview. Int. J. Pharm. Biol. Sci.

; 1(2): 1-11.

. Mohammad A, Kamran JN, Javed A,

Showkat RM. Three new esters from the

stem bark of Ficus bengalensis Linn. J.

Pharm. Res. 2010; 3(2): 352-5.

. A.Chatterjee. The treaties of Indian

medicinal plants. Vol.I; 1997. p. 39.

. Daniel, R.S., Mathew, B.C., Devi, K.S.,

Augusti, K.T. Antioxidant effect of two

flavonoids from the bark of Ficus

bengalensis Linn. in hyperlipidemic rats.

Ind J Exp Bio.1998; 36: 902ă6.

. Mousa O, Vuorela P, Kiviranta J, Wahab

SA, Hiltohen R, Vuorela H. Bioactivity of

certain Egyptian Ficus species. J

Ethnopharmacol. 1994; 41:71- 6.

. Anurag S, Moni K, Jagannadham MV.

Bengalensin, a Highly Stable Serine

Protease from the Latex of Medicinal

Plant Ficus bengalensis. J. Agric. Food

Chem. 2009; 57(23): 11120ă6.

. Aswar M, Aswar U, Watkar B, Vyas M,

Wagh A., Gujar KN Anthelmintic activity

of Ficus bengalensis Int J Green Ph.

;2:3.

. Patil V.V., Pimprikar R.B., Patil V.R.

Pharmacognostical Studies and

Evaluation of Anti-inflammatory Activity

of Ficus bengalensis Linn. JYP 2009;

(1)

. Vishnu N Thakare, Anupama A suralkar,

Avinash D Deshpande, Suresh R Naik.

Stem bark extraction of Ficus

bengalensis linn for anti inflammatory

and analgesic activity in animal models.

Ind J Exp Bio. 2010; 48:39-45.

. Vikas V. Patil, Bhangale S.C., Narkhede

S.B., Jawle N. M., Patil V. R. Analgesic

and Antipyretic Activities of Ficus

Bengalensis Bark. Int J Phar Res.2010;

(2).

. DJ Taur, SA Nirmal ,RY Patil, MD

Kharya. Antis tress and ant allergic

effects of Ficus bengalensis bark in

asthma. Nat Prod Res.

;21,14:1266-70.

. Pulok K. Mukherjee, Kakali Saha, T.

Murugesan, S.C. Mandal, M. Pal, B.P.

Saha. Screening of anti-diarrhoeal

profile of some plant extracts of a

specific region of West Bengal. Ind J

Ethnopharmacol. 1998;60: 85ă9.

. Mahalingam G, Krishnan K. Antidiabetic

and amelioferative potential of Ficus

bengalensis bark extract in

streptozotocin induced diabetic rats. Ind

J Biochem. 2008;23(4):394-400.

. Joglekar, J.C., Shrotri, D.S., Aiman, R.

and Balwani, J.H. A study on Ficus

bengalensis Lin. J. Ind. Med. Assoc.

: 40: 11-12.

. Vohra, S.B. and Parasar, G.C.

Antidiabetic studies on Ficus

bengalensis Linn. Ind. J. Pharmacy.

; 32: 68-9.

. Babu, B.V. Studies on Hypoglycemic

action of Ficus bengalensis (PhD

Thesis, Delhi University, Delhi).1985

. Kumar R.V., Augusti K.T. Antidiabetic

effect of a leucocynidin derivative

isolated from the bark of Ficus

bengalensis Linn. Ind J Biochem

Biophys.1989; 26 (6):400-4.

. Cherian S, Augusti K.T. To study the

Antidiabetic effects of a glycoside of

leucopelargonidin isolated from Ficus

bengalensis Linn. Ind J Exp Biol. 1993;

(1):26- 9.

. Geetha BS, Mathew BC, Augusti KT,

Hypoglycemic effects of

Leucodelphinidin derivative isolated from

Ficus bengalensis Ind J Physiol.

Pharmacol.1994; 38(3):220.

. Shukla, R., Anand, K., Prabhu, K.M. and

Murthy, P.S. Hypoglycemic effect of the

water extract of Ficus bengalensis in

alloxan recovered mildly diabetic and

severely diabetic rabbits. International.

J. Dia. Dev. Countries: 14, 78-81,

(1994).

. Shukla, R. Investigations on the

hypoglycemic activity of Ficus

bengalensis, PhD Thesis, Delhi

University, Delhi.1995.

. Agrawal V. Chauhan BM. A study on

composition and Hypolipidemic effect of

dietary fibre from some plant foods

.Plant foods hum Nutr. 1988; 38(2):189-

. Gabhe S.Y., P.A. Tatke, T.A. Khan

Evaluation of the Immunomodulatory

activity of the methanol extract of Ficus

bengalensis roots in rats. Ind J

Pharmacol. 2006; 38(4):271-5.

. Biswas TK, Mukherjee B. Plant

medicines of Indian origin for wound

healing activity: a review. Int J Low

Extreme Wounds. 2003;2(1): 25- 39.

. Ayyanar M, Ignacimuthu S. Herbal

Medicines for wound healing among

tribal people in Southern India:

Ethnobotanical and Scientific Evidences.

Int. J. Appl. Res. Nat. Prod. 2009; 2(3):

-42.

. Vipin K. Garg and Sarvesh K.Paliwal. J

adv Pharm Tech & Res. 2011; 2(2): 110-

. Nidhiya SR, Pai KSR, Rao CM. Growth

promoting potential of Ficus bengalensis

root extracts in immature female rats. J.

Pharm. Biol.2009; 47(4): 268-73.

. Ross IA. Medicinal Plants of the world,

Chemical constituents, Chemical

constituents. Traditional and Modern

Medicinal Uses, Humana Press, Totowa.

; p. 197-205

. Anonymous. „The Wealth of India- Raw

materials‰. Vol. VI:L-M; 1962. P. 281.

. Anonymous, „The Wealth of India- Raw

materials‰. Vol VI:L-M; 2005. P. 280.

. Muruganandan.S, Scrinivasan.K,

Gupta.S, Gupta.P.K and Lal.J. Effect of

mangiferin on hyperglycemia and

atherogenicity in streptazotocin diabetic

rats. J ethnopharm. 2005; 97: 497-501.

. Badmus.J.A, Adedosu.T.U, Fatoki.J.O,

Adegbite.V.S, Adaramoye.O.A,

Odunola.O.A. Lipid peroxidation

inhibition and antiradical activities of

some leaf fractions of Mangifera indica.

Acta Pol Pharm. 2011; 68(1) :23-9.

. Enikuomehin.O.A, Ikotun.T, Ekpo.E.J.

Evaluation of ash from some tropical

plants of Nigeria for the control of

sclerotium rolfsii sacc. On wheat

(Triticum aestivum L.). Mycopathologia.

;142(2):81-7.

. Zhu.X.M, Song.J.X, Huang.Z.Z,

Whu.Y.M and Yu.M.J. Antiviral activity of

Mangiferin against herpes simplex virus

type 2 in vitro.

ZhongguoYaoliXuebao.193; 14: 452-4.

. Godfrey S,Bbosa, Aloysius Lubega,

Nathan Musisi, David B, Kyegombe,

Paul Waako, Jasper Ogwal-Okeng,

OlwaOdyek. The activity of Mangifera

indica L. leaf extracts against the

tetanus causing bacterium, clostridium

tetani. Afri J of Ecology. 2007; 45:54-8.

. Ngozi.O Awa-Imaga. Possible antitrypanosomal effect of aqueous leaf

extracts of Mangifera indica on plasma

proteins of Trypanosomacongolenseinfected rats. J pharmacog and

phytotherapy.2011; 3(8):137-40.

. Scartezzini P, Speroni E. Review on

some plants of Indian traditional

medicine with antioxidant activity. J

Ethnopharmacol. 2000;71:23ă43.

. Anjaneyulu V, Babu JS, Connolly JD.

-Hydroxymangiferonic Acid from

Mangifera-Indica. Phytochem. 1994; 35:

-3.

. Selles AJN, Castro HTV, Aguero-Aguero

J, Gonzalez-Gonzalez J, Naddeo F, De

Simone F, Rastrelli L. Isolation and

quantitative analysis of phenolic

antioxidants, free sugars, and polyols

from mango (Mangifera indica L.) stem

bark aqueous decoction used in Cuba

as a nutritional supplement. J Agri and

Food Chem. 2002; 50: 762-6.

. Khan MN, Nizami SS, Khan MA, Ahmed

Z. New saponins from Mangifera indica.

J Nat Prod. 1993 ; 56: 767-70.

. Anjaneyulu V, Satyanarayana P,

Viswanadham KN, Jyothi VG, Rao KN,

Radhika P. Triterpenoids from Mangifera

indica. Phytoche. 1999; 50: 1229-36.

. Anjaneyulu V, Prasad KH, Ravi K,

Connolly JD. Triterpenoids from

Mangifera-Indica. Phytochem. 1985 ; 24:

-67.

. Anjaneyulu V, Ravi K, Prasad KH,

Connolly JD. Triterpenoids from

Mangifera-Indica. Phytochem. 1989 ; 28:

-7.

. Shibahara A, Yamamoto K, Shinkai K,

Nakayama T, Kajimoto G. Cis-9, cis-15-

octadecadienoic acid:a novel fatty acid

found in higher plants. Biochimi Biophy

Acta. 1993;1170:245ă52.

. Bandyopadhyay C, Gholap AS,

Mamdapur VR. Characterization of

Alkenylresorcinol in Mango (MangiferaIndica L) Latex. J Agri and Food Chem.

; 33: 377-9.

. Khan MA, Khan MN. Alkyl gallates of

flowers of Mangifera Indica. Fitoterapia.

;60:284.

. V. Anjaneyulu , P.Radhika. The

terpenoids and steroids from Mnagifera

Indica Linn. Ind J chem. 2000;

(B):883-93

. Knödler M, Berardini N, Kammerer DR,

Carle R, Schieber A. Characterization of

major and minor alk(en)ylresorcinols

from mango (Mangifera Indica L.) peels

by high-performance liquid

chromatography/atmospheric pressure

chemical ionization mass spectrometry.

Rapid Commun Mass Spectrom.

;21:945ă51.

. Martinez G, Delgado R, Perez G,

Garrido G, Nunez Selles AJ, Leon OS.

Evaluation of the in-vitro antioxidant

activity of Mangifera indica L: Extract

(Vimang). Phytother Res. 2000;14:424ă

. Pardo-Andreu GL, Sanchez-Baldoquín

C, Avila-González R, Yamamoto ET,

Revilla A, Uyemura SA, et al. Interaction

of Vimang (Mangifera indica L.extract)

with Fe(III) improves its antioxidant and

cytoprotecting activity. Pharmacol Res.

; 54:389ă95.

. Rocha Ribeiro SM, Queiroz JH, Lopes

Ribeiro ME, Campos FM, Pinheiro

Santana HM. Antioxidant in mango

(Mangifera indica L.) pulp. Plant Foods

Hum Nutr. 2007;62:13ă7.

. Gabino G, Deyarina G, Cheyla R,

Nunez-Selles AJ, Rene D. Scavenger

effect of a mango (Mangifera indica L.)

food supplement's active ingredient on

free radicals produced by human

polymorphonuclear cells and

hypoxanthineăxanthine oxidase

chemiluminescence systems. Food

Chem. 2008;107:1008ă14.

. Pardo Andreu G, Delgado R, Velho J,

Inada NM, Curti C, Vercesi AE.

Mangifera Indica L.extract (Vimang)

inhibits Fe2+- citrate-induced

lipoperoxidation in isolated rat liver

mitochondria. Pharmacol Res.

;51:427ă35.

. Sharma SR, Dwivedi SK, Swarup D.

Hypoglycemic potential of Mangifera

indica leaves in rats. Int J Pharmaco.

;35:130.

. Aderibigbe AO, Emudianughe TS, Lawal

BA. Antihyperglycaemic effect of

Mangifera indica in rat. Phytother Res.

;13:504ă7.

. Aderibigbe AO, Emudianughe TS, Lawal

BA. Evaluation of the antidiabetic action

of Mangifera indica in mice. Phytother

Res. 2001;15:456ă8.

. Perpétuo GF, Salgado JM. Effect of

mango (Mangifera indica, L.) ingestion

on blood glucose levels of normal and

diabetic rats. J Plant Foods Hum Nutr.

;58:1ă12.

. Ojewole JA. Antiinflammatory, analgesic

and hypoglycemic effects of Mangifera

indica Linn.(Anacardiaceae) stem-bark

aqueous extract. Methods Find Exp Clin

Pharmacol. 2005;27:547ă54.

. Amrita B, Liakot A, Masfida A, Begum R.

Studies on the antidiabetic effects of

Mangifera indica stem-barks and leaves

on nondiabetic, type 1 and type 2

diabetic model rats. Bangladesh J

Pharmacol. 2009;4:110ă4.

. Muruganandan S, Scrinivasan K, Gupta

S, Gupta PK, Lal J. Effect of mangiferin

on hyperglycemia and atherogenicity in

streptozotocin diabetic rats. J

Ethnopharmacol. 2005;97:497ă501.

. Rolo AP, Palmeira CM. Diabetes and

mitochondrial function: Role of

hyperglycemia and oxidative stress.

Toxicol Appl Pharmacol. 2006;212:167ă

. Zhu XM, Song JX, Huang ZZ, Whu YM,

Yu MJ. Antiviral activity of mangiferin

against herpes simplex virus type 2 in

vitro. Zhongguo Yao Li Xue Bao.

;14:452ă4.

. Zheng MS, Lu ZY. Antiviral effect of

mangiferin and isomangiferin on herpes

simplex virus. Chin Med J.

;103:160ă5.

. Guha S, Ghosal S, Chattopadyay U.

Antitumor, immunomodulatory and antiHIV effect of mangiferin: A naturally

occurring glucosylxanthone.

Chemotherapy. 1996;42:443ă51.

. Garcia D, Escalante M, Delgado R,

Ubeira FM, Leiro J. Anthelminthic and

antiallergic activities of Mangifera indica

L.stem bark components Vimang and

mangiferin. Phytother Res.

;17:1203ă8.

. Rivera DG, Balmaseda IH, Leon AA,

Hernandez BC, Montiel LM, Garrido GG,

et al. Anti-allergic properties of

Mangifera indica L.extract (Vimang) and

contribution of its glucosylxanthone

mangiferin. J Pharm Pharmacol.

;58:385ă92.

. Muanza DN, Euler KL, Williams L,

Newman DJ. Screening for antitumor

and anti-HIV activities of nine medicinal

plants from Zaire. Int J Pharmacol.

;33:98.

. Aswal BS, Bhakuni DS, Goel AK, Kar K,

Mehrota BN, Mukhrjee KC. Screening of

Indian plants for biological activity: Part

X. Indian J Exp Biol. 1984;22:312ă32.

. Peng ZG, Luo J, Xia LH, Chen Y, Song

S. CML cell line K562 cell apoptosis

induced by mangiferin. Zhongguo

Shiyan Xue Ye Xue Za Zhi.

;12:590ă4.

. Yoshimi N, Matsunaga K, Katayama M,

Yamada Y, Kuno T, Qiao Z, et al. The

inhibitory effects of mangiferin: A

naturally occuring glucosylxanthone, in

bowel carcinogenesis of male F344 rats.

Cancer Lett. 2001;163:163ă70.

. Doughari, J. H. and Manzara, S. In vitro

antibacterial activity of crude leaf

extracts of Mangifera indica Linn. Afri J

Microbio Res. 2008;2:67-72.

. K.P. Latha, M. S. Latha, H. M. Vagdevi,

S. B. Virupaxappa. Anti inflammatory

activity of Mangifera indica L. Var.

Rasapuri Root extracts. J Chem and

Pharm Res.2012; 4(1), 333-6.

. Saruth Nithitanakool, Pimolpan

Pithayanukul , Rapepol Bavovada.

Antioxidant and Hepatoprotective

Activities of Thai Mango Seed Kernel

Extract. Planta Med. 2009; 75(10): 1118-

. Jagetia GC, Baliga MS. Radioprotection

by mangiferin in DBAxC57BL mice: a

preliminary study. Phytomedicine.2005;

: 209-15

. Yoshikawa M, Shimoda H, Nishida N,

Takada M, Matsuda H. Salacia reticulata

and its polyphenolic constituents with

lipase inhibitory and lipolytic activities

have mild antiobesity effects in rats. T J

Nutri. 2002; 132: 1819-24

. Kirtikar KR, Basu BD. Indian medicinal

plant. 2nd ed. Dehradun: Oriental

enterprises; 2001. p. 1543ă4.

. Singh BP, Wayne F. Whitehead Pointed

gourd: Potential for temperate climates.

J Janick. 1999; 118:27ă35.

. Nadkarni AK. Indian Materia Medica. 3rd

ed. Mumbai: Popular prakashan Pvt.

Ltd; 1982. p. 1236ă7.

. Khare CP. Encyclopedia of Indian

medicinal plants. Berlin, Heidelberg;

New York: Springer-Verlag; 2004. p.

ă8.

. Chopra RN, Nayar SL, Chopra IC,

Glossary of Indian Medicinal plants,

CSIR, New Delhi, 2002, p.340.

. Kongton S, Chemical study of bioactive

constituents from Trichosanthes

cucumerina root and fruit juice, Mahidol

University, 2003. P.80-5.

. Ali N, Mohammed Sultan, Kenoth R,

Swamy MJ, Purification,

physicochemical characterization,

saccharide specificity, and chemical

modification of a Gal/GalNAc specific

lectin from the seeds of Trichosanthes

dioica. Arc of Biochem and Biophy.

; 432: 212ă21.

. Chandrasekhar B, Mukherjee B,

Mukherjee SK, Blood sugar lowering

effect of Trichosanthes dioica Roxb. in

experimental rat models. Int J Cru Drug

Res. 1988; 26: 102ă6.

. Rai PK, Jaiswal D, Singh RK, Gupta RK,

Watal G. Glycemic Properties of

Trichosanthes dioica leaves. Pharm

bio.2008; 46(12): 894-9.

. Rai DK, Rai PK, Jaiswal D, Sharma B,

Watal G. Effect of water extract of

Trichosanthes dioica fruits in

streptozotocin induced diabetic rats. Ind

J Clinical Biochem. 2008; 23 (4): 387-90.

. Ghaisas MM, Tanwar MB, Ninave PB,

Navghare VV, Deshpande T,

Hepatoprotective activity of aqueous &

ethanolic extract of T. dioica in ferrous

sulphate induced liver injury.

Pharmacologyonline.2008; 3: 127-35.

. Sharmila BG, Kumar G, Rajasekhara

PM. Cholesterol-lowering activity of the

aqueous fruit extract of Trichosanthes

dioica in normal and streptozotocin

diabetic rats. J Clin Dia Res.2007; 1(4):

-69.

. Sharma G, Pant MC. Influence of

alcoholic extract of whole fruit of T.

dioica, on blood sugar, serum lipids,

lipoproteins & faecal sterols in normal

albino rabbits. Ind J clinical biochem.

; 1: 53-6.

. Fulzule SV, Satturwar D, Joshi SB,

Studies on anti-inflammatory activity of a

poly herbal formulation- Jatydi Ghrita.

Ind drugs.2001; 39(1): 42-4.

. Hariti M, Rathee PS. Antifungal activity

of the unsaponifiable fraction of the fixed

oil of Trichosanthes seeds. Asian J

chem.. 1996; 8(1): 180-2.

. Hariti M, Rathee PS. Antibacterial

activity of the unsaponifiable fraction of

the fixed oil of Trichosanthes seeds.

Asian J Chem1995; 7 (4): 909-11.

. Rai PK, Mehta S, Gupta RK, Watal G. A

Novel Antimicrobial Agents

Trichosanthes dioica. Int J Pharma and

Bio Sci.2010; 1(3): 1-9.

. Shivhare Y, Singh P, Rajak H, Patil UK,

Pawar RS. Antioxidant potential of

Trichosanthes dioica Roxb (fruits).

Phcog J.2010; 2(6): 107-11.

. Shivhare Y, Singh P and Patil UK,

Healing Potential of Trichosanthes

dioica Roxb. On Burn Wounds. Res J

Pharmacol and pharmacodyn. 2010;

(2): 168-71.

. Singh KP, Singh RH, Clinical

investigation of importance of T. dioica.

J Res Ayurveda, siddha. 1985;6(2):

- 40.

Downloads

Published

31-12-2013

How to Cite

1.
Pulak Majumder, Paridhavi M. A Comprehensive Ethno-Phyto-Pharmacological Review on Novel Indian Medicinal Plants Used In Polyherbal Formulations. ijp [Internet]. 2013 Dec. 31 [cited 2024 Dec. 23];5(4):394-41. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/279

Issue

Section

Review Article