Anti-inflammatory activity of Syzygium Cumini leaves

Authors

  • Jain A I.P.S. College of Pharmacy, Gwalior, M.P, India
  • Sharma S I.P.S. College of Pharmacy, Gwalior, M.P, India
  • Goyal M I.P.S. College of Pharmacy, Gwalior, M.P, India.
  • Dubey S I.P.S. College of Pharmacy, Gwalior, M.P, India.
  • Jain S I.P.S. College of Pharmacy, Gwalior, M.P, India.
  • Sahu J I.P.S. College of Pharmacy, Gwalior, M.P, India.
  • Sharma A I.P.S. College of Pharmacy, Gwalior, M.P, India.
  • Kaushik A I.P.S. College of Pharmacy, Gwalior, M.P, India.

Keywords:

Anti-inflammatory, Ethyl acetate, Methanol, yzygium cumini

Abstract

The Syzygium cumini (Myrtaceae) is a popular traditional medicinal plant in India. This study was intended to evaluate the antiinflammatory activity of ethyl acetate and methanol extracts of S.cumini leaves in carrageenan induced paw oedema in wistar rats at the dose level of 200 and 400 mg/kg administrated orally. Both the extracts exhibited significant anti-inflammatory activity, which supports the traditional medicinal utilization of the plant. This study established anti-inflammatory activity of leaves of S.cumini.

References

Bhuiyan MA, Mia MY, Rashid MA.

Antibacterial principles of the seed of

Eugenia jambolana. Banga J. Bot.1996;

(2): 239-241.

Crunkhon P, Meacock SER. Mediators of

the inflammation induced in the rat paw by

carrageenan. Br. J. Pharmacol.1971; 42:

-402.

DiRosa M, Giroud JP, Willoughby DA.

Studies of the acute inflammatory response

induced in rats in different sites by

carrageenan and turpentine. J. Pathol 1971;

: 15 -29.

Dixon WJ, Jennrich R BMDP Statistical

Software, University of California Press.

Los Angeles. USA ;1990.

Ecobichon DJ The basis of toxicology

testing. RC press, New York: 1997; 43-86.

Indira G, Mohan RJ National Institute of

Nutrition Indian council of Medical

Research, 1993: Hyderabad; 34-37.

Kusumoto IT, Nakabayashi T, Kida H

Screening of various plant extracts used in

ayurvedic medicine for inhibitory effects on

human immunodeficience virus type I

(HIV-I) protease 1995; 12: 488-493.

Mossa JS, Rafatullah S, Galal AM, AlYahya MA Pharmacological studies of

Rhus retinorrhaea. Int. J. Pharmacognosy

; 166: 96-103.

Muruganandan S, Srinivasan K, Chandra S,

Tandan SK, Lal J, Paviprakash V. Antiinflammatory activity of Syzygium cumin.

Fitoterapia 2001; 72: 369-375.

Ravi K, Satish Sekar D, Subramanian S

Hypoglycemic activity of Inorganic

constituents of Eugenia jambolana seed on

streptozocininuced diabetes in rats Biol.

Trace Ele. Res.2004; 99: 145-155.

Slowing K, Carretero E, Villar A Antiinflammatory activity of leaf extracts of

Eugenia jambos on rats J. Ethnophamacol.

; 43: 9-11.

Vinegar R, Schreiber W, Hugo R Biophasic

development of carrageenan oedema on

rats. J. Pharmacol. Exp. Ther. 1969; 66: 96-

Winter CA, Risley EA, Nuss GW

Carrageenan induced oedema hind paw of

the rats as an assay for anti-inflammatory

drug Proc. Soc. Biol. Med. 1969; 111: 544-

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Published

30-06-2010

How to Cite

1.
Jain A, Sharma S, Goyal M, Dubey S, Jain S, Sahu J, Sharma A, Kaushik A. Anti-inflammatory activity of Syzygium Cumini leaves. ijp [Internet]. 2010 Jun. 30 [cited 2024 Dec. 23];2(2):124-6. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/27

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Original Research Articles