Phytochemical Investigation and Antibacterial activity of leaf and stem extracts of Sapium indicum Linn

Authors

  • Swati Sucharita Panda Swati Sucharita Panda C/o Dr. N.K Dhal Environment and Sustainability Department Institute of Minerals and Materials Technology Bhubaneswar-751013, India
  • Kalpana Sahoo Swati Sucharita Panda C/o Dr. N.K Dhal Environment and Sustainability Department Institute of Minerals and Materials Technology Bhubaneswar-751013, India
  • Dilip Khatua Swati Sucharita Panda C/o Dr. N.K Dhal Environment and Sustainability Department Institute of Minerals and Materials Technology Bhubaneswar-751013, India
  • Nabin Kumar Dhal Swati Sucharita Panda C/o Dr. N.K Dhal Environment and Sustainability Department Institute of Minerals and Materials Technology Bhubaneswar-751013, India

Keywords:

Mangrove, Sapium indicum, phytochemical screening, antimicrobial activity

Abstract

Plants have provided a source of inspiration for novel drugs compounds. In this study, the antibacterial activity was of Sapim indicum Linn. collected from mangroves area of Odisha was made against some bacterial pathogens by disc diffusion method. All the four crude extracts (methanol, chloroform, hexane, and petroleum ether) tested, showed significant antimicrobial activity with zone of inhibitions ranging between 9-31 mm. Among all the solvent, methanol extracts of both stem and leaf exhibited the highest inhibition zone against Salmonella typhi. Further evaluation of minimal inhibitory concentration (MIC) showed values ranging from 4-5.6 mg/ml. Preliminary phytochemical screening revealed the presence of alkaloids, steroids, triterpenoids, saponins, flavonoids, reducing sugars and protein in almost all extract. The present study of in vitro antibacterial assay and preliminary phytochemical analysis may open new vistas for identifying potential bioactive molecules for chemical, pharmacological and herbal industry.

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Published

30-09-2012

How to Cite

1.
Swati Sucharita Panda, Kalpana Sahoo, Dilip Khatua, Nabin Kumar Dhal. Phytochemical Investigation and Antibacterial activity of leaf and stem extracts of Sapium indicum Linn. ijp [Internet]. 2012 Sep. 30 [cited 2024 Dec. 6];4(3):409-13. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/195

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Original Research Articles