Antimicrobial activity of Saraca indica against clinical pathogens

Authors

  • Hema TA Department of Microbiology, Malankara Catholic College, Mariagiri, Kaliakkavilai, 629 153, Tamil Nadu.
  • Parvathy J Department of Microbiology, Malankara Catholic College, Mariagiri, Kaliakkavilai, 629 153, Tamil Nadu.
  • Shiny M Department of Microbiology, Malankara Catholic College, Mariagiri, Kaliakkavilai, 629 153, Tamil Nadu.
  • S.Sujatha Department of Microbiology, Malankara Catholic College, Mariagiri, Kaliakkavilai, 629 153, Tamil Nadu.

Keywords:

Saraca indica, antimicrobial activity, alkaloids, Rf value

Abstract

The antimicrobial activity of flowers of the medicinal plant Saraca indica collected from from the regions of Ambalathara, Kerala, South India was checked against the clinical pathogens by well diffusion method. Saraca i1ndica showed highest antimicrobial activity on methanolic extracts. The phytochemical evaluation showed the presence of alkaloids, tannins, proteins and reducing sugars. With the help of column chromatography the methanolic extract was purified and highest antimicrobial activity was observed in the concentration 2:8. By thin layer chromatography the compounds are separated and the Rf value obtained was 0.6. The compound responsible for the antimicrobial activity was partially identified as alkaloids

References

. Arora DS, Kaur JK. Antibacterial

activity of some Indian, medicinal

plants. Journal of natural medicines.

; 61:313-319.Prusti A, Mishra

SR, Sahoo S, Mishra SK.

Antibacterial activity of some Indian

medicinal plants. Ethnobotanical

Leaflets. 2008; 12:227-230.

. Pradhan P, Joseph L, Gupta V,

Chulet R, Arya H, Verma R, Bajpai

A. Journal of chemical and

pharmaceutical research. 2009;

(1): 62-71.

. Duraipandiyan V, Muniappan A,

Savarimuthu I. Antibacterial activity

of some ethnomedicinal plants used

by Paliyar tribe from Tamil Nadu,

India. Complementary and

alternative medicine. 2006; 10:6-35.

. Sainath R, Prathiba J Malathi R.

Antimicrobial properties of the stem

bark of Saraca indica

(Caesalpiniaceae). European

Review for Medical and

Pharmacological Sciences. 2009;

: 371-374.

. Unni BG, Borah A, Singh HR.

Phytochemical and antibacterial

study of North East India on

Escherichia coli. Asian J. Exp. Sci.

; 23(1):103-108.

. Solanki,R. Some medicinal plants

with antibacterial activity.

International journal of

comprehensive pharmacy. 2010;

(10):1-4.

. Raman S, Sultana N, Anwar MN.

Invitro Antimicrobial activity of

Holarrifine-24ol isolated from the

stem bark of Holarrhena

antidysenterica. International journal

of agriculture and biology. 2004;

:698-700.

. Bauer AW, Kirby WMM, Sherris JC

and Truck M. Antibiotic susceptibility

testing by standard single disk

diffusion method. Am. J. Clin. Path.

;45:493-496.

. Kepm W. Qualitative Organic

Analysis: Spectrochemical

Techniques. 2nd Edn., McGraw- Hill,

London and New York, ISBN

1986;pp: 197.

. Dabur R, Gupta A, Mandal TK,

Singh DD, Bajpai V, Gurav AM,

Lavekar GS. Antimicrobial activity

of some Indian medicinal plants.Afr.

J. Trad. Comp. Alt. Med. 2007; 4:

-318.

. Narang GD, Nayar S, Mcndiratta

DK. Antibacterial activity of some

indigenous drugs, J. Vet. Animal

husb. Res. 1962; 6(1): 22-25.

. Cibin TR, Gayathri DD, Abraham A.

Chemoprevention of skin cancer by

the flavonoid fraction of Saraca

asoka. Phytotherapy Research .

; 24:666–672.

. Cai L, Wu CD. Compounds of

Syzygium aromaticum possessing

growth inhibitory activity against oral

pathogens. J of Nat. Prod. 1996;

(9): 987–990.

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Published

30-06-2012

How to Cite

1.
Hema TA, Parvathy J, Shiny M, S.Sujatha. Antimicrobial activity of Saraca indica against clinical pathogens. ijp [Internet]. 2012 Jun. 30 [cited 2024 Dec. 23];4(2):272-6. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/174

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Original Research Articles