Phytochemical analysis and screening of antibacterial activity of some selected Indian medicinal plants

Authors

  • C. Arora Chugh Department of Chemistry, L.P. University, JalandharDelhi G. T. Road (NH-1), Phagwara, Punjab (India)- 144402
  • D. Bharti Department of Chemistry, L.P. University, JalandharDelhi G. T. Road (NH-1), Phagwara, Punjab (India)- 144402

Keywords:

Medicinal Plants, bacterial strain, phytochemical screening

Abstract

Phytochemical screening and evaluation of antibacterial activity of ten plant species namely Aloe barbadensis, Aegel marmelos, Azadirachta indica, Bahunia variegate, Cannabis sativa, Emblica officinalis, Eugenia jambolana, Gmelina arborea, Nerium oleander and Vitex negundo have been carried out against six bacterial strains namely Escherichia coli 101, Escherichia coli 119, Micrococcus luteus, Bacillus subtilus, Bacillus cereus and Pseudomonas fluorescence. All the plants species taken in present study have shown the presence of tannin, flavonoids, terpenoids and alkaloids. Pholobatanins have found to be present in Aegel marmelos, Bahunia variegate and Eugenia jambolana while cardiac glycosides have been shown positive test on Aloe barbadensis, Azadirachta indica, Cannabis sativa, Nerium oleander and Vitex negundo. Methanol extract of Emblica officinalis have been shown significance potential against all test pathogens except Pseudomonas fluorescence followed by Nerium oleander, Azadirachta indica and Bahunia variegate.

References

. Thomson WAR. (Ed.), Medicines

from the Earth, McGraw-Hill Book

Co, Maidenhead, United Kingdom,

, 155.

. Stockwell C. Nature’s Pharmacy,

Century Hutchinson Ltd., London,

United Kingdom, 1988.

. Edeoga1 HO, Okwu DE, Mbaebie

BO. Phytochemical constituents of

some Nigerian medicinal plants Afr J

Biotech., 2005; 4, 685-688.

. Satish S, Raghavendra MP,

Raveesha KA. Evaluation of the

Antibacterial Potential of Some

Plants Against Human Pathogenic

Bacteria, Advances in Biological

Research, 2008; 2 (3-4): 44-48.

. Ceylan E, Fung DYC. Antimicrobial

activity of spices. J Rap Meth Auto

Microbiol 2004; 12: 1-55.

. Marjorie C. Plant products as

antimicrobial agents, Clinical

Microbiology Reviews, 1999; 12,

-582.

. DMPRD (Division of Medical Plants

Research and Development,

Department of Medical Science,

Ministry of Public Health). Hand

Book of Medicinal Plant for Primary

Public Health. Text and Journal

Corporation Co., Ltd. Press,

Bangkok. 1990; p. 53.

. Duke JA. Handbook of

Phytochemical Constituents of

GRAS Herbs and Other Economic

Plants. CRC Press, London, UK,

. Hon-Ning L. Chinese Medicinal

Herbs of Hong Kong, vol. 2. Hang

Chiewing Sa Kwang, Hong Kong,

. Husain A, Virmani OP, Popli SP.

Dictionary of Indian Medicinal

Plants. CIMPA, Lucknow, Republic

of India, 1992.

. Harbone JB. Phytochemical Method:

A Guide to Modern Technique of

Plant Analysis (2nd Edn), Chapman

and Hall, London, 1984; 19, 37 –

. Ahmad J, Mehmood Z, Mohammad

F. Screening of some Indian

medicinal plants for their

antimicrobial properties. J

Ethnopharmacol, 1998; 62, 183-

. Jamil A, Shahid M, Khan M, Ashraf

M. Pak J Bot., 2007; 39(1), 211-222.

. Samy RP. Antimicrobial activity of

some medicinal plants from India,

Fitoterapia, 2005; 76, 697-99.

. Parekh J, Karathia N, Chanda S.

Evaluation of antibacterial activity

and phytochemical analysis of

Bauhinia variegata L. bark, African

Journal of Biomedical Research,

; 9: 53 – 56.

. Appendino G, Gibbons S, Giana A,

Pagani A, Grassi G, Stavri M, Smith

E, Rahman MM. Antibacterial

Cannabinoids from Cannabis sativa:

A Structure—Activity Study, J. Nat.

Prod., 2008; 71(8), 1427-30.

. Saeed S, Tariq P, Antibacterial

activities of Emblica officinalis and

Coriandrum sativum against gram

negative urinary pathogens, Pak J

Pharm Sci., 2007; 20(1), 32-35.

. Zaika LL. Spices and herbs: their

antimicrobial activity and its

determination, J Food Safety., 1975;

: 97-118.

. Nair R, Kalariya T, Chanda S.

Antibacterial activity of some

selected Indian medicinal flora, Turk

J Biol., 2005; 29: 1-7.

. Arora C, Vashali, Synergistic effect

of antimicrobial constituents of Vitex

negundo with metal ferrocyanides,

Progressive Agriculture: An

International Journal, 2009; 9(1): 30-

. Adome RA, Gachihi JW. Onegi B,

Tamale J. Apio SO. The cardiotonic

effect of the crude ethanolic extract

of Nerium oleander in the isolated

guinea pig hearts, African Health

Science, 2003; 3(2): 77-82.

. Krishnaiah D, Devi T, Bono A,

Sarbatly R. Studies on

Phytochemical Constituents of Six

Malaysian medicinal plants, Journal

of Medicinal Plants Research,

; 3(2): 067-072.

. Perez C, Pauli M, Bazerque P. An

antibiotic assay by agar-well

diffusion method. Acta Biol Med Exp

;15:113-5.

. Awadh Ali NA, Juelich WD, Kusnick

C, Lindequist U. Screening of

Yemeni medicinal plants for antibacterial & cytotoxic activities. J

Ethnopharmacol, 2001; 74, 173-79.

. Kaushik RD, Garg GK, Sharma G,

Arora C. Antibacterial activity of

plant extracts from Uttaranchal Hills,

India. Allelopathy Journal, 2003,

(2), 205-214.

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Published

30-06-2012

How to Cite

1.
C. Arora Chugh, D. Bharti. Phytochemical analysis and screening of antibacterial activity of some selected Indian medicinal plants. ijp [Internet]. 2012 Jun. 30 [cited 2024 Sep. 28];4(2):261-5. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/172

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Original Research Articles