Polyphenolic composition of Lantana camara and Lippia chevalieri, and their antioxidant and antimicrobial activities

Authors

  • M.J. Bangou Laboratoire de Biochimie et de Chimie Appliquées (LABIOCA), U.F.R.-S.V.T., Université de Ouagadougou, 09 BP 848 Ouagadougou 09, Burkina Faso
  • N. Almaraz-Abarca Centro Interdisciplinario de Investigación para el Desarrollo Integral Regional, Instituto Politécnico Nacional, Unidad Durango. Becaria COFAA; Sigma 119, Fraccionamiento 20 de Noviembre II, Durango, Dgo., 34220, México
  • N.T.R. Méda Laboratoire de Biochimie et de Chimie Appliquées (LABIOCA), U.F.R.-S.V.T., Université de Ouagadougou, 09 BP 848 Ouagadougou 09, Burkina Faso
  • B. Zeba Laboratoire d’Enzymologie de la ChimioRésistance Bactérienne (LECRB), U.F.R.- S.V.T., Université de Ouagadougou, 09 BP 848 Ouagadougou 09, Burkina Faso
  • M. Kiendrebéogo Laboratoire de Biochimie et de Chimie Appliquées (LABIOCA), U.F.R.-S.V.T., Université de Ouagadougou, 09 BP 848 Ouagadougou 09, Burkina Faso
  • J. Millogo-Rasolodimby Laboratoire de Biologie et Ecologie Végétales, U.F.R.-S.V.T., Université de Ouagadougou, 09 BP 848 Ouagadougou 09, Burkina Faso
  • O. G. Nacoulma Laboratoire de Biochimie et de Chimie Appliquées (LABIOCA), U.F.R.-S.V.T., Université de Ouagadougou, 09 BP 848 Ouagadougou 09, Burkina Faso

Keywords:

Verbenaceae, HPLC-DAD, antioxidant activity, antimicrobial activity, polyphenolic compounds

Abstract

In the present study, the antioxidant and antibacterial activities of methanolic extracts of two Verbenaceae (Lantana camara L. and Lippia chevalieri Moldenke: aerial part) were investigated. Their polyphenolic composition in the ethyl acetate and aqueous fractions were characterized by HPLC-DAD. The antioxidant capability of the methanolic extracts was assessed by the Ferric Reducing Antioxidant Power (FRAP) and the scavenging activity of the free radical 2,2-diphenyl-1- picrylhydrazyl (DPPH). The Minimum Inhibitory Concentrations (MIC) of the methanolic extracts (25 µg mL-1), and the minimum bactericidal concentrations (MBC) (12.5 µg mL-1) against 13 pathogenic bacteria and four serotyped bacteria from the American Type Culture Collection (ATCC) were also determined by the solid agar dishes diffusion method. The results indicated that the L. chevalieri extracts are rich in phenolic compounds (among the 27 polyphenolic compounds detected, 20 belong to L. chevalieri) and showed the highest antioxidant activities, simultaneously on iron (III) to iron (II)- reducing activity and the radical scavenging activity. However, L. camara displayed the best and the broadest antimicrobial spectrum, especially on Shigella flexneri and Pantoea sp. (two Gram-negative strains of bacteria). The nature of polyphenolics compounds detected (phenol acid and flavone) in L. camara can justify this activity.

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Published

31-03-2012

How to Cite

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M.J. Bangou, N. Almaraz-Abarca, N.T.R. Méda, B. Zeba, M. Kiendrebéogo, J. Millogo-Rasolodimby, O. G. Nacoulma. Polyphenolic composition of Lantana camara and Lippia chevalieri, and their antioxidant and antimicrobial activities. ijp [Internet]. 2012 Mar. 31 [cited 2024 Dec. 3];4(1):115=-124. Available from: https://ijp.arjournals.org/index.php/ijp/article/view/152

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